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Wednesday, 2 August 2023

#Tomato Rich in Carotenoids Inhibits #Hyperglycemia by Normalizing the Levels of HbA1, According to Studies

Kyle J. Norton

Hyperglycemia found in patients with diabetes is a condition of abnormally high blood glucose in the bloodstream.
Most cases of hyperglycemia are a result of poor diabetic control including unhealthy food and physical activity choices, medical conditions, and nondiabetes medications, particularly in people who frequent skipping or not taking enough glucose-lowering medication.

* Foot Complications are the condition caused by nerve damage that controls the leg, leading to numbness and severe pain in the feet. in the blood but also can cause kidney failure.

* Kidney disease is a condition that can reduce the function of the kidney in filtering the waste in the blood.

* Hypertension is a condition of high blood pressure that can lead to an increase in the risk heart attack, stroke, and eye problems.

* Stroke caused by abnormally high blood pressure and high blood glucose.

* Gastroparesis is a condition caused by the reduced function of vagus nerves that control the movement of food.

Some researchers suggested by the change of lifestyle and moderate exercise accompanied by taking your medicine daily, hyperglycemia is preventable in diabetes.

The Mayo Clinic Staff in the article " Diabetes management: How lifestyle, daily routine affect blood sugar", wrote, "Healthy eating is a cornerstone of healthy living — with or without diabetes. But if you have diabetes, you need to know how foods affect your blood sugar levels".

"Physical activity is another important part of your diabetes management plan. When you exercise, your muscles use sugar (glucose) for energy. Regular physical activity also helps your body use insulin more efficiently".


And, "Insulin and other diabetes medications are designed to lower your blood sugar levels when diet and exercise alone aren't sufficient for managing diabetes. But the effectiveness of these medications depends on the timing and size of the dose. Medications you take for conditions other than diabetes also can affect your blood sugar levels".

In other words, by following a healthy lifestyle including diet, moderate exercise, and taking the required medicines hyperglycemia is controllable.

Tomato is a red, edible fruit, genus Solanum, belongs to the family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

With an aim to find a potential compound or whole food for the treatment of hyperglycemia, researchers examined the relationship between hyperglycemia and both serum carotenoids and the intake of vegetables and fruits.

The study induced 133 subjects with a history of diabetes mellitus or hyperglycemia diagnosed using a 5.6% cutoff value for hemoglobin A1c (High HbA1c group, n = 151) recruited from among inhabitants of a rural area in Hokkaido, Japan.


High HbA1c between 5.7% and 6.4% is an indication of a higher risk of diabetes.
According to the return of a questionnaire administered by public health nurses on the Intake frequencies of vegetables and fruits,* The odds ratio (OR) for high HbA1c was 0.49 on high intake frequency of carrot and pumpkin and the OR for DM was 1.21 (95% Cl: 0.79-1.84)
* There are no significant relationships between high HbA1c and intake frequencies of other vegetables and fruits.

* The ORs on high serum levels of alpha- and beta-carotenes, lycopene, beta-cryptoxanthin and zeaxanthin, and lutein were 0.38 (0.22-0.65), 0.35 (0.21-0.59), 0.57 (0.35-0.93), 0.35 (0.20-0.59), and 0.88 (0.54-1.46) for high HbA1c, respectively.


In other words, tomatoes may have a strong effect against the onset of hyperglycemia by normalizing the levels of HbA1c.

Based on the finding, researchers said, "Intake of vegetables and fruits rich in carotenoids might be a protective factor against hyperglycemia".

Taken together, tomatoes may be considered functional foods for the prevention and treatment of hyperglycemia, pending the confirmation of the larger sample size and multicenter human study.

Intake of carotenoids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Relationship between serum carotenoids and hyperglycemia: a population-based cross-sectional study by Suzuki K1, Ito Y, Nakamura S, Ochiai J, Aoki K. (PubMed)
(2) Effects and Underlying Mechanisms of Bioactive Compounds on Type 2 Diabetes Mellitus and Alzheimer's Disease by Li R1, Zhang Y1, Rasool S1, Geetha T1, Babu JR. (PubMed)

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