Kyle J. Norton
Scientists may have found a pungent spice that processes the potential to reverse metabolic dysfunction, according to studies.
Metabolic dysfunction is a medical condition characterized by the improper function of the liver or pancreas.
In some cases, metabolic dysfunction may also be caused by enzyme deficiency due to a defective gene, including Antitrypsin (AAT) deficiency, a common metabolic liver disease that affects infants, children, and adults.
The liver, the large organ in humans plays a critical role in breaking down old or damaged blood cells. and a central role in all metabolic processes, including fat metabolism by breaking down fat to energy for the body's needs.
On the other hand, the pancreas also converts the food we eat into energy for the body's cells by regulating blood glucose through the production of insulin.
Dysfunction of one of the 2 organs not only has a strong impact on the energy levels in the body but also increases the risk of diabetes and nonalcoholic liver disease.
According to the statistics provided by the Centers for Diseases Control and Prevention, in the US, among adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 1988–1994 to 2007–2012, increasing from 25.3% to 34.2%. The rise of metabolic dysfunction is probably associated with widespread obesity in the general population, some researchers suggested.
The risk factors associated with the onset of metabolic dysfunction include workers exposed to natural asbestos and mixed asbestos stock dust, improper nutrition, excessive intake of food with a high content of free sugar, saturated fatty acids, and common salt with a lack of chicken meat, cereals, fish, vegetables, fruits, and cultured milk foods in the diet and excessive body weight.
Most people with metabolic dysfunction do not experience any symptoms. However, if you have a large waist circumference and experience symptoms of high blood glucose, increased thirst and urination, fatigue, and blurred vision, you may have a metabolic disorder. Please check with your doctor to rule out the possibility.
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the modulation of metabolism evaluated the effects and the mechanisms of ginger extract intake in the metabolic disturbances animal model. Mice selected for the study were induced metabolic dysfunction by a high-refined carbohydrate (HC) diet.
Ginger extract at doses of 200, 600, and 1800 mg/kg supplemented in the daily food of obese Balb/c mice for an 8-week showed a metabolic protective effect by preventing the increase of adiposity induced by HC diet, improving lipid profile, and promoting the decrease of inflammatory markers.
Furthermore, treated mice also exerted a decrease in the recruitment of cells visualized in vivo in the microvasculature of adipose tissue, a decrease in inflammatory cytokines, and an increase in adiponectin serum levels.
The finding suggested that ginger processes anti-metabolic dysfunction in obese mice induced by a long-term high-refined carbohydrate (HC) diet.
In order to reveal more information about ginger anti-metabolic syndrome activity, used in traditional medicine, researchers examined the herbal effects on hyperlipidemia, hyperglycemia, oxidative stress, and inflammation.
Ginger showed a potency activity in reducing the onset of metabolic syndrome through
mediating the several transcription factors associated with the metabolic function, including activated glucose and fatty acid uptake.
The results indicated the beneficial effects of ginger on obesity and related complications in MetS.
Taken together, ginger may be considered a functional remedy for the prevention and treatment of metabolic dysfunction, pending the confirmation of a larger sample size and multicenter human study.
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale Rosc.) Ameliorated Metabolic and Inflammatory Dysfunction Induced by High-Refined Carbohydrate-Containing Diet in Mice by Oliveira CT1, Lacerda DR1, Zicker MC1, Martins LB1, Teixeira MM2, Bello de Araujo RL1, Ferreira AVM. (PubMed)
(2) Beneficial effects of ginger Zingiber officinale Roscoe on obesity and metabolic syndrome: a review by Wang J1,2, Ke W1, Bao R1, Hu X1,2, Chen F. (PubMed)
(3) [Risk factors and development of metabolic disorders in workers of "Uralasbest" enterprise][Article in Russian] by Prianichnikova NI, Mazhaeva TV, Dubenko SÉ, Obukhova TIu, Chirkova IA.(PubMed)
(4) Metabolic Syndrome Prevalence by Race/Ethnicity and Sex in the United States, National Health and Nutrition Examination Survey, 1988–2012 by ORIGINAL RESEARCH — Volume 14 — March 16, 2017. (CDC)
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