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Monday, 26 June 2023

#Herbal #Artichoke Combined with Probiotics For the Treatment of #ChronicConstipation, Researchers Suggest

Kyle J. Norton

Constipation is a condition of hard and dry stool that are infrequent or hard to pass.
Acute constipation reversed in a few days mostly is caused by staying in a sitting position for long periods of time that kinks up your colon and restrains stool from passing through.

Chronic constipation is a condition characterized by difficult, infrequent, or perceived incomplete evacuation of bowel movements with less than 3 bowel movements a week,

Chronic constipation other than structural and medical problems is normally caused by a diet with low fiber accompanied by the intake of certain medications such as calcium channel blockers, and narcotics.

The total fiber intake per day is 25-35 grams, is recommended for people with constipation and general health, depending on your sex, age, and weight.

If you are taking the requirement of fiber daily, but experience symptoms of excess colon gas and flatus, you should cut down on soluble fiber first.

In order to maintain good colon health against constipation, people with chronic constipation with no structural and medical problems should follow a high-fiber diet accompanied by increased fluid intake and moderate exercise.

Some researchers suggested that there is a correlation between psychological disorders such as depression in the risk of constipation.

Dr. Janique G. Jessurun, in the study of the relationship between psychiatric diagnoses and constipation wrote, "In the stratum of patients older than 60 years, all psychiatric categories except for substance-related disorders were significantly associated with a higher prevalence of constipation".

And, " In the elderly, all measured psychiatric diagnoses are strongly associated with an increased prevalence of constipation".

In other words, adults who are 60 years of age and over with psychiatric disorders are at a higher risk of constipation.

Artichoke is a perennial thistle of Cynara cardunculus species of the Cynara genus, belonging to the family Carduoideae native to Southern Europe around the Mediterranean.

The herbal plant has been used in traditional medicine as a liver protective and detoxified agent, and to treat digestive disorders, abdominal pain gas, bloating, etc.

Researchers on the finding of natural therapeutics for chronic constipation researchers evaluated the effects of probiotic-enriched artichokes on treatment preference, symptom profile, and short-chain fatty acid (SCFA) production in constipated subjects, compared with ordinary artichokes.

The double-blind method included 20 constipated patients (3M/17F; 38.8 ± 14.4 years) using a computer-generated randomization list. Each patient consumed 180 g per day of ordinary artichokes or artichokes enriched with Lactobacillus paracasei IMPC 2.1 for 15 days (daily dose of 2 × 10(10) CFU).

80% of participants preferred probiotic-enriched artichokes to ordinary ones. Satisfactory relief of symptoms was significantly higher (P = 0.0014) during the probiotic-enriched artichoke period.

The Bristol chart cluster scores were significantly higher in the combined treatment group (3.3 ± 1.2, 2.9 ± 1.3 2.2 ± 1.2) compared to the baseline, ordinary artichokes, and probiotic-enriched ones, respectively.
Furthermore, GSRS constipation was significantly lower (13.9 ± 0.9, 10.2 ± 0.8, 8.3 ± 0.9; P = 0.032) in the combined treatment group compared to the probiotic group and baseline.

Based on the findings, researchers wrote, "This trial shows a positive effect on symptoms in constipated patients after intake of probiotic-enriched artichokes".

In order to understand more information about artichokes in the promotion of constipation, researchers assessed the suitability of some vegetables, particularly olives, and artichokes, to vehicle probiotic strains into the gastrointestinal tract.

The study included 8 volunteers (3M/5F age 40+/-14 y) who integrated their normal diet with artichokes (180 gr) enriched with 20 billion of L. paracasei LMGP22043 for 15 days.

There were no significant differences in the microbiological counts throughout the experimental period. However, the treatment group showed a significant increase in butyric and valeric acids with a concomitant decrease in lactic acid.

The treatment also reduced the fecal beta-glucuronidase activity and abdominal distension and feeling of incomplete evacuation.

Taken altogether, artichoke combined with probiotics may be considered a functional formula for the treatment of patients with chronic constipation with no side effects, pending the validation of a larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Randomised clinical trial: efficacy of Lactobacillus paracasei-enriched artichokes in the treatment of patients with functional constipation--a double-blind, controlled, crossover study by Riezzo G1, Orlando A, D'Attoma B, Guerra V, Valerio F, Lavermicocca P, De Candia S, Russo F.(PubMed)
(2) Effects of probiotic Lactobacillus paracasei-enriched artichokes on constipated patients: a pilot study by Valerio F1, Russo F, de Candia S, Riezzo G, Orlando A, Lonigro SL, Lavermicocca P. (PubMed)
(3) The Relation between Psychiatric Diagnoses and Constipation in Hospitalized Patients: A Cross-Sectional Study by Janique G. Jessurun,1,2 Peter N. van Harten,1,3 Toine C. G. Egberts,2,4 Ysbrand J. Pijl,1 Ingeborg Wilting,2,4 and Diederik E. Tenback. (Hindawi)

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