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Thursday 29 June 2023

#Carrots Inhibit Oxidative Stress Against the Onset of #Hyperglycemia and #Prediabes Through Their Antioxidant Activities, Researchers Say

Kyle J. Norton

Carrots may have a profound and positive effect in normalizing the levels of sugar in the blood, some scientists suggested.
Hyperglycemia is a condition characterized by abnormally high levels of plasma glucose circulating in the blood.

The syndrome does not cause any symptoms until the levels of sugar are elevated above 180 to 200 milligrams per deciliter (mg/dL), or 10 to 11 millimoles per liter (mmol/L).


Hyperglycemia is considered an early culprit for the onset of type 2 diabetes. Untreated managed type 1 and 2 diabetes that causes prolonged periods of high blood glucose may induce some unpredictable complications, such as nerve, kidney, foot, and eye damage.

If you are diabetic and have fasted and after meal fasting glucose of higher than 130 mg/dL and over 140 mg/dL respectively, you are considered to have the onset of hyperglycemia.

The causes of hyperglycemia are associated with a number of factors. However, researchers as of today, do not know why people with the same health condition and family history, are susceptible to the risk of the condition, while others do not.

Some researchers suggested that people who have diabetes skip or forget their insulin or oral glucose-lowering medicine, eat far more carbohydrates compared to the normal intake of insulin, and don't take part in the daily exercise are most dangerous to have hyperglycemia.

Compared to hyperglycemia, prediabetes is a condition in which blood sugar levels are higher than normal but lower than those of diabetics.

If you are diabetic, and experiencing symptoms of fruity-smelling breath, persistent gastrointestinal discomforts, shortness of breath, and dry mouth, you have hyperglycemia. Please make sure you check with your doctor to rule out the possibility.

In serious cases, some diabetes with hyperglycemia also experience symptoms of confusion, stomach pain, and coma.

Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belonging to the family Apiaceae, native to Asia and Europe.

In the study to investigate the relationship between hyperglycemia and both serum carotenoids and intake of vegetables and fruits in a total of 284 subjects, 133 with a history of diabetes mellitus or 151 with hyperglycemia diagnosed using a 5.6% cutoff value for hemoglobin A1c (High HbA1c group, n = 151) from among inhabitants of a rural area in Hokkaido, Japan, match with healthy control researchers found that

* The odds ratio (OR) for high HbA1c was 0.49 (95% confidence interval: 0.29-0.85) on high intake frequency of carrot and pumpkin.

* There are no significant relationships between high HbA1c and intake frequencies of other vegetables and fruits.

These results suggested that carrots and pumpkins have a positive effect in reducing the levels of blood glucose in patients with high HbA1c, compared to the intake of other fruits and vegetables.


Furthermore, in the evaluation of serum carotenoid levels among residents with hyperglycemia who were screened in a health check-up program for the inhabitants living in a rural area of Hokkaido compared with those with normal levels, researchers showed that
* Serum levels of alpha, beta-carotenes, and cryptoxanthin were lower among those with high HbA1c newly detected than among those with a normal level.

* Observation on diabetics who have already been under control in the clinic, showed no significant differences in serum levels of carotenoids, or lipids such as total cholesterol and TBARS compared to other groups

The information indicated that serum carotenoid levels can be used as an indicator of food intake and oxidative stress for the prediabetic condition since newly detected hyperglycemia tends to show lower serum antioxidant levels such as beta-carotene, and higher serum lipid peroxide levels.
Interestingly, researchers after taking other factors into account said, " males who currently smoked and drank alcohol, the intake frequency of carrot or pumpkin was significantly lower for those with high HbA1c than for the others".

Taken together, people who have diabetes and are at higher risk may want to add a portion of carrots into their daily diet as a preventive measure.

Since the studies quoted in this article are observational bases, therefore, further data collection on large example size and multi-center studies performed with human consumption of whole food during the course of the disease will be necessary to complete the picture of carrot's anti-hyperglycemic possibilities.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Relationship between serum carotenoids and hyperglycemia: a population-based cross-sectional study by Suzuki K1, Ito Y, Nakamura S, Ochiai J, Aoki K.(PubMed)
(2) [A study on serum carotenoid levels of people with hyperglycemia who were screened among residents living in a rural area of Hokkaido, Japan].
[Article in Japanese] by Suzuki K1, Ito Y, Otani M, Suzuki S, Aoki K(PubMed)

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