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Wednesday, 18 March 2020

Omega-3 Fatty Acids, A potential Treatment for Cardiovascular Diseases

By Kyle J. Norton


Cardiovascular disease (CVD) is a group of conditions associated with the heart and blood vessels.

Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.

According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.

Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.

The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.

High blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.

In other words, anything that serves to damage the inner lining of blood vessels and impedes the transportation of oxygen and nutrition to the heart can be defined as a risk of heart disease. Here are some early indication of heart disease symptoms.

According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.

The most common complications of heart diseases are heart failure, the condition occurs when the heart cannot adequately pump blood throughout the body and heart attack, it occurs when the coronary arteries narrow caused by building up of plaques that block the blood supply to the heart.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effects of omega-3-fatty acids on cardiovascular diseases (CVD).

According to the tested analysis,
* The administration of omega-3 fatty acids showed significantly reduced risk for sudden death caused by cardiac arrhythmias and all-cause mortality in patients with coronary heart disease.

* Furthermore, omega-3 fatty acids inhibited the expression of hyperlipidemia and hypertension. 

* There are no significant drug interactions with oral administration of omega-3 fatty acids.

More profoundly, the American Heart Association recommends the consumption of two servings of fish per week for persons with no history of coronary heart disease and at least one serving of fish daily for those with known coronary heart disease.

Additionally, approximately 1 g/day of eicosapentaenoic acid plus docosahexaenoic acid is recommended for cardioprotection. Higher dosages of omega-3 fatty acids are found to ameliorate the elevated triglyceride levels (2-4 g/day).

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention and treatment of CVD, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Omega-3 polyunsaturated fatty acids for cardiovascular diseases: present, past and future by Watanabe Y1, Tatsuno I. (PubMed)
(2) Omega-3 fatty acids and cardiovascular disease by Jain AP1, Aggarwal KK, Zhang PY. (PubMed)

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