Herbal Enchinanea Enhanced Sperm Quality and Quantity in Male Fertility In Vitro

By Kyle J. Norton

Anti-fertility is an act with the intention to prevent, reduce or destroy fertility by using substances such as contraceptives, herbal medicine in under-developing the world.

Contraceptives are conventional medicines that allow women to enjoy sex without the risk of getting pregnant. The contraceptive pill is the most common contraceptive agent used in the Western world.

Many women also use a contraceptive pill for the treatment of irregular menstruation, painful or heavy periods, endometriosis, acne, and premenstrual syndrome (PMS).

The most common side effects of the contraceptive pill include gastrointestinal discomforts, intermenstrual spotting, breast tenderness, headaches, and migraine, mood changes, missed periods and vaginal discharge.

Infertility is a condition of the inability of a couple to conceive after 12 months of unprotected sexual intercourse. It affects over 5 million couples alone in the U. S. and many times more in the world. Because of unawareness of treatments, only 10% seek help from a professional specialist.

Male infertility is a medical condition associated with the male's inability to cause pregnancy in a fertile female.

Male infertility accounts for 40–50% of all cases of infertility, affecting over 7% of all men.
Most cases of male infertility are the results of deficiencies in the semen, and semen quality that lead to reduced function of male fecundity.

More than 40% of the infertility of a couple is caused by the female inability to fertilize.

The most common causes of infertility in the female in the US. are aging, medical condition of endometriosis and polycystic ovarian syndrome (PCOS) which have a strong interruption of the female menstrual cycle, sexually transmitted infections (STIs) and obesity.

Echinacea also is known as purple coneflowers, is a flowering plant of the genus Echinacea, belongings to the family Asteraceae, native to eastern and central North America. The herb has been used in traditional and herbal medicine to treat or prevent colds, flu, infections by stimulating the immune function, etc.

On finding a potential phytochemical for the treatment of chronic diseases, researchers examined the effect of the supplementation of ginger and echinacea extract, as natural antioxidant agents, in freezing extender on the quality and fertility potential of ram epididymal spermatozoa after cryopreservation.

The study included Epididymal spermatozoa isolated from 40 testicles from 20 rams, with motility >80% and total morphological abnormalities <10% that were divided into 7 aliquots used for cryopreservation.

According to the analysis of the semen samples that were re-suspended with basicTris egg yolk diluent containing ginger and echinacea extracts (5, 10 and 20 mg/l)after 7-10 days,

* The supplementation of ginger at a concentration of 10 mg/l, as well as the addition of 10 and 20 mg/l echinacea extract significantly improved total motility and velocity parameters.

* The status of acrosome integrity and lipid peroxidation significantly improved in spermatozoa when supplemented with 10 mg/l ginger and 20 mg/l echinacea extract.

* 5 mg/l ginger extract and 20 mg/l echinacea extract significantly improved mitochondrial activity.

* The highest ratio of the dispersion of sperm chromatin was observed in spermatozoa treated with 10 mg/l ginger extract.

* The cleavage rate was markedly higher in matured oocytes that were fertilized with frozen spermatozoa treated with 20 mg/l ginger extract and 10 mg/l echinacea.

After talking about other factors into account, researchers said, "The application of ginger and echinacea extract resulted in improvement in the quality and fertility of frozen-thawed spermatozoa".

Taken altogether, herbal Enchinanea used alone or combined with ginger may be considered adjunct therapies in the treatment of male infertility, pending to the confirmation of the larger sample size and multicenter human study.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Ginger and echinacea extracts improve the quality and fertility potential of frozen-thawed ram epididymal spermatozoa by Merati Z1, Farshad A. (PubMed)