Common Fig or Fig (Ficus carica) Protects the Kidneys Against Renal Toxicity

By Kyle J. Norton

The kidneys, a pair of bean-shaped organs on either side of your spine are the second detoxed organ after liver by removing wastes or toxins in the blood come from the normal breakdown of active muscle and from the food you eat.

Kidney dysfunction can reduce the body's ability to clean your blood, filter extra water out of your blood, leading to fluid retention and high blood pressure in the early stage.

Chronic kidney disease is a gradual loss of kidney function over time. Chronic kidney failure is the end stage of chronic kidney disease which has been found in high numbers in patients with diabetes, high blood pressure and other disorders.

Unlike many diseases, kidney diseases often have no symptoms until it is in a very advanced stage.

Acute kidney dysfunction or acute kidneys failure is a result of insufficient blood flow to the kidneys such as renal hypertension. These types of kidneys dysfunction can be cured if the causes are found.

Most cases of acute kidney dysfunction may be associated with toxin accumulated in the kidney organs, leading to the condition of nephrotoxicity.

Renal toxicity or nephrotoxicity in most cases is toxicity in the kidneys caused by toxic chemicals and medications.

The most common symptoms of renal toxicity may cause reduced kidney function in eliminating toxins, leading to a reduced amount of urine. swelling of your legs, ankles, and feet from retention of fluids.

In a serious case, the condition can also result in unexplained shortness of breath. excessive drowsiness or fatigue. persistent nausea. confusion. pain or pressure in your chest.

The World Health Organization wrote, "Exposure to mercury – even small amounts – may cause serious health problems, and is a threat to the development of the child in utero and early in life.".

And, " Mercury may have toxic effects on the nervous, digestive and immune systems, and on lungs, kidneys, skin, and eyes".

Fig is a species of F. carica, belonging to the family Moraceae. It is a deciduous shrub, native to Southeast Asia. The tree can grow to a height of 33 ft and the fruit can be as large as 2.0 inches.

On finding a natural whole food for the treatment of kidney diseases, researchers examined the hydroalcoholic extract of ficus carica (HEFC) on gentamicin (GM)-induced nephrotoxicity.

The study included rats that were pre-fed experimental diets for 8 days and received GM (100 mg/kg body weight/day) treatment for 8 days while still on diet.

According to the tested differentiation, hydroalcoholic extract of ficus carica (HEFC) retard the progression of certain types of cancers, cardiovascular and renal disorders.

HEFC inhibited the GM nephrotoxicity by attenuating the increased serum creatinine and blood urea nitrogen.

Furthermore, HEFC also inhibited the GM increased MDA level and decreased catalase, reduced glutathione.

More precisely, HEFC alone increased antioxidant expression such as CAT concentration, GSH content and decreased oxidative stress MDA level. 

Based on the findings, researchers said, "HEFC supplementation ameliorated GM-induced specific metabolic alterations and oxidative damage due to its intrinsic biochemical/antioxidant properties".

Taken altogether, common fig processed abundantly anthocyanin may be considered a natural anti-oxidative stress remedy against kidney toxicity, pending to the confirmation of the larger sample size and multicenter human study.

Intake of SFN in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective role of hydroalcoholic extract of Ficus carica in gentamicin induced nephrotoxicity in rats Kaksaheb J. Kore*, Rajkumar V. Shete, Babasaheb N. Kale and Amit S. Borade. (INTERNATIONAL JOURNAL OF PHARMACY & LIFE SCIENCES)