Healthy Food Leeks, the Promising Anticancer Veggie

By Kyle J. Norton

Cancer is a group of medical and chronic diseases characterized by cell growth disorderly and uncontrollably in the tissue of specific organs in the body.

Over time, the alternative cells induced tumor may become progressively worse and damage other healthy tissues, depending on the grade of the tumor.

At the later stage, the most invasive tumor can induce secondary metastasis by spreading to other organs in the body via lymph or blood.

According to the National Cancer Institute, approximately 38.4% of men and women will be diagnosed with cancer at some points during their lifetimes, according to the data from 2013–2015.

The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

The causes of cancer are unknown. age, excessive alcohol drinking, exposure to cancer causing-substances, diseases associated with chronic inflammation, unhealthy diet, hormones therapy, use of immunosuppression are some of the prevalent factors involved in the onset of cancer.

However, most people with some of the aforementioned risk factors have never developed cancer.

Cancers are the second leading cause of death worldwide besides heart diseases.

The most common types of cancer in Canada include lung, colorectal, breast and prostate cancers. And these 4 cancers are account for half of all cancers diagnosed in Canada.

Believe it or not, 1/4 of cancers death are due to lung cancer.

Depending on types of cancer, people with cancers may experience general and specific symptoms.
Some researchers suggested that the risk of cancers in obese individuals may correlate to the promotion of the Western diet over the past few decades.

Leek is a genius of Allium, belonging to the vegetable family vegetable Alliacaea, the same as onion and garlic. Leeks are easy to grow from seed and usually reach maturity in the autumn months, and have few pest or disease problems.

On finding a potential plant that processes anti-tumor growth activity researchers compared the anticancer properties various sulfur and organic compounds like S-allyl mercaptocysteine, quercetin, flavonoids, and ajoene found on leek on cancer.

According to the analysis,

* These compounds with various mechanisms such as hindering cell cycle, inhibiting signaling pathways, inducing apoptosis, and antioxidant activity interfere with diverse stages of formation, growth, differentiation, and metastasis of cancer cells.

* Similar to garlic and onion, other species such as leeks have exhibited anticancer activities, so that active natural molecules extracted from them might serve as possible anticancer agents.

Moreover, the study on anticancer effects of onion and leek extracts on MCF-7 human breast cancer cell cultured in complete media at 37 °C and subjected to different treatments that involved varying concentrations (10, 50, and 100 μg/mL) of onion and leek extracts for 24, 48, and 72 h of incubation suggested that 

* The water leek extract proved to be the most effective extract at 50 μg/mL, whereby it showed a significant inhibition ability due to the presence of entadamide A-β-D-glucopyranoside.

* Both extracts induced cell death probably was also associated with the presence of other bioactive compounds.

Taken altogether, leeks may be considered a functional food for the prevention and treatment of cancer, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Comparative Study of Onion (Allium cepa) and Leek (Allium ampeloprasum): Identification of Organosulphur Compounds by UPLC-QTOF/MS and Anticancer Effect on MCF-7 Cells by Zamri N1, Hamid HA. (PubMed)
(1) Allium vegetables for possible future of cancer treatment by Asemani Y1, Zamani N2, Bayat M1, Amirghofran Z. (PubMed)