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Wednesday 5 February 2020

Devil's claw (Harpagophytum procumbens) Suppresses the Symptoms of Osteoarthritis

By Kyle J. Norton

Osteoarthritis is a type of musculoskeletal disorders (MSDs) and medical condition mostly caused by work-related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time.

More precisely, Osteoarthritis (OA), a form of arthritis, is a condition of aging causes of wear and tear on a joint, affecting over 25 million people in the United States alone. 

University of Porto Medical School indicated that one must understand the differences in prevalence and incidence estimates of osteoarthritis (OA), according to case definition, in the knee, hip and hand joints(3).

The most common symptoms associated with OA are aching pain, stiffness, or difficulty of moving the joint or joints. 

The pain usually gets worse in a change of weather, at night and in the advanced diseases, the pain can occur even at rest. 

Today management of osteoarthritis (OA) focuses on pain relief and improved physical function through pharmacological, nonpharmacological, and surgical treatments.

Osteoarthritis getting worse overtime can induce complications of
* Gout
The forming of sodium urate crystals forming in and around your joints, due to high levels of urate can result from inflammatory arthritis or gout.

* Chondrocalcinosis
The forming of calcium pyrophosphate crystals to form in the cartilage, due to osteoarthritis (OA) can cause calcification.
*  Rapid, the complete breakdown of cartilage.

* Osteonecrosis, is a result of bone death due to the collapse of the architecture of bone, as the result of a number of conditions ultimately leading to an impairment of blood supply to the bone tissue.

* Stress fractures
The common complication found in 0.3%-0.8% of patients who suffer from rheumatic diseases as a result of multifactorial overuse injuries(97).

*  Bleeding inside the joint.

* Infection in the joint

Devil's claw also known as the wood spider, is a plant of genus Harpagophytum in the family of Pedaliaceae, native to South Africa. 

The plant has been used as an herb in traditional and herbal medicine to treat fever, rheumatoid arthritis, skin, gallbladder, pancreas, stomach and kidneys conditions, etc.

On finding a natural ingredient for the prevention and treatment of chronic inflammatory diseases, scientists investigated the effectiveness of a dietary supplement including hydrolyzed gelatin, chondroitin sulfate, glucosamine sulfate, and devil's claw and bamboo extracts for pain reduction and improvement of functional capacities in patients with osteoarthritis (OA) of the knee and/or hip (REDART study).

According to the results of a total of 130 patients with OA who were recruited from Spanish hospitals received the dietary supplement for 6 months,
* Patients (N = 78) showed a reduction of pain of 3.77 ± 1.77 points after 6 months (p < .0001) in the VAS.

* The total reduction in the Lequesne Functional Index was 6.30 ± 4.08 points after 6 months (p < .0001), with significant reductions in all subindexes of the scale.

* A similar pattern was found for the WOMAC index, with an overall reduction of 22.49 ± 14.03 points after 6 months (p < .0001) and significant reductions in all subindexes.

Based on the results, researchers suggest, "No major adverse events were noted during the treatment. This exploratory study shows that treatment with the dietary supplement significantly reduces pain and improves locomotor function in patients with OA of the knee and/or hip".

Taken altogether, Devil's claw (Harpagophytum procumbens) may be considered a remedy for the treatment of osteoarthritis, pending to the confirmation of the larger sample size and multicenter human study.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effectiveness of a Dietary Supplement Containing Hydrolyzed Collagen, Chondroitin Sulfate, and Glucosamine in Pain Reduction and Functional Capacity in Osteoarthritis Patients by Puigdellivol J1, Comellas Berenger C1, Pérez Fernández MÁ2, Cowalinsky Millán JM3, Carreras Vidal C4, Gil Gil I5, Martínez Pagán J6, Ruiz Nieto B7, Jiménez Gómez F8, Comas Figuerola FX9, Aguilar Hernández ME. (PubMed)
(2) The effect of osteoarthritis definition on prevalence and incidence estimates: a systematic review by Pereira D1, Peleteiro B, Araújo J, Branco J, Santos RA, Ramos E.(PubMed)
(3) 
The Research and Studies of Musculo-Skeletal disorders(MSDs) - Osteoarthritis: The Complications by Kyle J. Norton

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