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Thursday, 9 January 2020

Green Peas (Pisum Sativum), the Anti Cancer Functional Foods

By Kyle J. Norton

Cancer is the group of chronic diseases associated with the cell growth disorderly and uncontrollably due to the alternation of DNA.

Most cases of cancer begin in the cells on the surface of the inner lining tissues of organs or glands. At the early stage, most cancers are asymptomatic. However, after penetrating through the deeper layers and colonizing the entire organs or glands, cancer cells at the advanced stage also can travel a distance away from the original site to induce secondary metastasis.

At this advanced stage, most cancers not only can induce common symptoms of gastrointestinal discomforts, unintended weight loss, loss of appetite and fatigue but also localized symptoms depending on the affected tissues and organs.

The American cancer society statistics showed that in 2018,1,735,350 new cases were diagnosed, representing more than 4,700 new cancer diagnoses each day.

The lifetime probability of being diagnosed with cancer is 39.7% for men and 37.6% for women.

The cancer mortality is the calculation of the number of cancer deaths (cancer mortality) in cancer patients

Based on 2011–2015 deaths, the cancer motility rate is 163.5 per 100,000 men and women per year.

The number of cancer survivors is expected to increase to 20.3 million by 2026.


Green peas are species of Pisum Sativum belongings to the family Fabaceae and native to western Asia from the Mediterranean Sea to the Himalaya Mountains. The pea is a green, pod-shaped vegetable and a cool-season crop grown in many parts of the world.

On finding a potent ingredient for the treatment of cancers,  researchers investigated the impact of green pea (GP) extract in the prevention of cancer.

According to the results of tested assays,
The extracts of P. sativum showed a pharmacologically active in the promotion of the anticancer activity.

* Compared to the effect of Bowman-Birk trypsin-chymotrypsin inhibitor, P. sativum may be a potential cancer chemopreventive agent.

 P. sativum exerted inhibitory activities on the growth of human colorectal adenocarcinoma HT-29.

* Extracted lectin from leaves and buds of P. sativum showed cytotoxicity to many cancer cell lines such as MCF-7 (breast), HepG-2 (liver), HEP-2 (larynx), and HCT-116 (colon).

The seed extracts also exerted cytotoxic effects on malignant cell lines, including LS174 (colon), MDA-MB-453 (breast), A594 (lung), and K562 (blood).

Taken altogether, green peas may be considered a functional food for the prevention and treatment of cancers, pending to the confirmation of the larger sample size and multicenter human study.



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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Pea, Pisum sativum, and It's Anticancer Activity by Runchana Rungruangmaitree and Wannee Jiraungkoorskul. (PubMed)

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