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Saturday 10 April 2021

Mixture of Kale (Brassica Oleracea) and Payapa Shows Promising Results for the Treatment of Colitis in Vivo

By Kyle J. Norton

Colitis is medical a condition characterized by the inflammation of the large intestine, including the colon, caecum, and rectum.

There is no exact cause of colitis. Certain risk factors such as colon infection, inflammatory bowel disease (Crohn's disease, ulcerative colitis), ischemic colitis, allergic reactions, and microscopic colitis have been found to increase the risk of the onset of the condition.

The most common symptoms of colitis are totally depending on the types, including abdominal pain, cramping, diarrhea, with or without blood in the stool.

Types of colitis according to the Catholic University of the Sacred Heart, are including
Depending on the causes, colitis can be classified into microscopic colitis, ischemic colitis, segmental colitis associated with diverticula, radiation colitis, diversion colitis, eosinophilic colitis, and Behcet's colitis, particularly in those associated with inflammatory bowel disease (IBD), such as ulcerative colitis (UC).

Some cases of colitis are also induced by the overactive immune system in the response of unharmful allergens.

Most common symptoms of colitis depending on the cause of the disease, including abdominal pain, cramping, diarrhea, with or without blood in the stool.

Some patients in the early phase of colitis may also experience symptoms of fever, chills, fatigue, and skin inflammation.

If you experience some of the aforementioned symptoms, please make sure that you check with your doctor to rule out the possibility.

Treatment of colitis is totally depending on the causes. Infected colitis is treated with antibiotics. 

However, treatment of non-infection colitis is focusing on symptoms relief, supportive care, and maintaining adequate hydration and pain control.

If you are taking antibiotics for the treatment of colitis, please discuss the side effect with your doctor.

Kale is a species of Brassica Oleracea, belonging to the family Brassicaceae, native to coastal southern and western Europe. Since kale's leave is highly nutritious and easy to grow with a range of long season from the middle of winter through the beginning of spring, it is cultivated as foods in most parts of Europe.

On finding a potential wholefood for the treatment of colitis researchers examined the evaluate the effect of dried vegetables as a prebiotic and as an intestinal anti-inflammatory in the rat colitis model.

Rats selected to the study were given orally, 500 mg/kg of rat weight of three treatments of dried vegetables: papaya, kale and the mixture of both vegetables (60% of kale plus 40% of papaya) with colitis were induced by intracolonic administration of trinitrobenzene sulfonic acid (TNBS) after the two weeks of treatment.

According to the prebiotic assay, administration of the mixture showed to modulate the bacterial flora in both the healthy rats and rats with colitis induced by TNBS compared to the veggie individual treatment

Furthermore, the application of the mixture showed a strong intestinal anti-inflammatory effect in the colitic rats observed by the reduced levels of pro-inflammatory colonic iNOS, TNFa and IL-1b  expression

Taken altogether, kale used a combination with  papaya may be considered a mixture for the treatment of colitis




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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of kale and papaya supplementation in colitis induced by trinitrobenzenesulfonic acid in the rat Cibele Lima de Albuquerque a,*, Monica Comlada b , Desiree Camuesco b , Maria Elena Rodrı´guez-Cabezas b , Anderson Luiz-Ferreira a , Ana Nieto c , Alba Regina Monteiro de Souza Brito a , Antonio Zarzuelo b , Julio Ga´lvez. (EL SEVIER)

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