Inflammation is a natural response of the immune system in which the white blood cells of the first line of defense try to protect the body by destroying the foreign pathogens which try to enter the body through wound or tissue damage.
Inflammatory cytokines induce the Inflammatory processes in the body, triggered by the body's own immune system.
During the acute phase of infection, overproduction of proinflammatory cytokines may cause damage to nearby healthy cells, leading to the formation of scars.
Most cases of infection are stopped at the acute phase of infection as the immune system successfully kills off all invaders in a brief battle.
Some researchers suggested the immune system has evolved to protect our body over thousands of years with an aim to kill off all pathogens within a period in the range of 3 to 8 weeks. Otherwise, it will adapt to the new change, leading to chronic inflammation.
In other words, chronic inflammation happens when the immune response lingers, causing low-grade inflammation. Chronic inflammation over time may damage the body tissues and organs.
During the acute phase of infection, overproduction of proinflammatory cytokines may cause damage to nearby healthy cells, leading to the formation of scars.
Most cases of infection are stopped at the acute phase of infection as the immune system successfully kills off all invaders in a brief battle.
Some researchers suggested the immune system has evolved to protect our body over thousands of years with an aim to kill off all pathogens within a period in the range of 3 to 8 weeks. Otherwise, it will adapt to the new change, leading to chronic inflammation.
In other words, chronic inflammation happens when the immune response lingers, causing low-grade inflammation. Chronic inflammation over time may damage the body tissues and organs.
In some cases, the infection may be latent in which the pathogen remains within the body for a long time without producing any symptoms, such as the hepatitis virus.
Diseases associated with chronic inflammation include cancer, heart disease, rheumatoid arthritis, type 2 diabetes, and obesity.
Anti-inflammatory protein in the body displays anti-inflammatory properties against the risk of autoimmune diseases and immune pathologies such as rheumatoid arthritis, psoriasis, or organ rejection.
Diseases associated with chronic inflammation include cancer, heart disease, rheumatoid arthritis, type 2 diabetes, and obesity.
Anti-inflammatory activity is the use of a substance or treatment for the treatment of od inflammation or swelling.
Dandelion is a herbaceous perennial plant, genus Taraxacum, belongings to the family Asteraceae, native to temperate regions of the world. It has been used in traditional and herbal medicine to treat gout, eczema, acne, gall bladder, kidney, liver, and urinary disorders, hypoglycemia, dyspepsia with constipation, edema, blood pressure, and heart weakness, chronic joint, skin diseases, etc.
In other words, TO suppressed the LPS-induced nuclear translocation of NF-κB, without affecting the pro-inflammatory cytokine MAPK activation.
On finding a natural ingredient for the treatment of chronic inflammatory diseases, scientists examined the anti-inflammatory activity of taraxacum officinale (TO) filtered methanol extracts in LPS-stimulated human umbilical vein endothelial cells (HUVECs).
According to the results from the assays on HUVECs pretreated with 100 μg/ml TO for 1 h and then incubated with 1 μg/ml LPS for 24 h, TO filtered methanol extracts dramatically inhibited LPS-induced endothelial cell-monocyte interactions by reducing vascular cell adhesion molecule-1 and monocyte chemoattractant protein-1 associated with cellular inflammation found in various immunological disorders, including rheumatoid arthritis, asthma, transplant rejection.
Furthermore, TO filtered methanol extracts also inhibited the production of pro-inflammatory proteins found in inflammatory subjects.
Based on the results, researchers said, "Our findings demonstrated that methanol extracts of TO could attenuate LPS-induced endothelial cell activation by inhibiting the NF-κB pathway. These results indicate the potential clinical benefits and applications of TO for the prevention of vascular inflammation and atherosclerosis".
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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction by Liu Q1, Zhao H2, Gao Y1, Meng Y1, Zhao XX1, Pan SN. (PubMed)
(2) Anti-inflammatory evaluation of the methanolic extract of Taraxacum officinale in LPS-stimulated human umbilical vein endothelial cells by Jeon D1,2, Kim SJ3, Kim HS. (PubMed)
Taken altogether, dandelion may be considered a remedy for the treatment of diseases associated with chronic inflammatory diseases, pending to the confirmation of the larger sample size and multicenter human study.
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Effects of Dandelion Extract on the Proliferation of Rat Skeletal Muscle Cells and the Inhibition of a Lipopolysaccharide-Induced Inflammatory Reaction by Liu Q1, Zhao H2, Gao Y1, Meng Y1, Zhao XX1, Pan SN. (PubMed)
(2) Anti-inflammatory evaluation of the methanolic extract of Taraxacum officinale in LPS-stimulated human umbilical vein endothelial cells by Jeon D1,2, Kim SJ3, Kim HS. (PubMed)
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