Metabolic syndrome is a group of conditions associated with an increased risk of cardiovascular disease and types 2 diabetes, including high blood pressure, sugar, cholesterol and triglyceride levels and excess body fat around the waist.
Epidemiological studies suggested if you have 3 of the above syndromes, you have metabolic syndrome.
According to statistics, metabolic syndrome is a growing prevalence in the Western world, In the US, 30% of Americans are living with metabolic syndrome,
In other words, 1 in 5 people in Canada has metabolic syndrome, affecting 19.1% of all Canadian adults.
The CDC statistic suggested, among US adults aged 18 years or older, the prevalence of metabolic syndrome rose by more than 35% from 25.3% to 34.2% according to the data from 1988–1994 to 2007–2012.
The exact causes of metabolic syndrome are unidentified. However, researchers suggested eating too many calories, particularly in a high-fat diet, physical inactivity, and excessive weight gain are some of the most common and prevalent factors in elevated the risk of metabolic syndrome in the Western world.
Most people with metabolic syndrome do not experience any symptoms, until the condition progression into a later stage, overtimes, leading to insulin resistance and plagues built-up on the wall of the arteries.
Other risk factors that increased the risk of metabolic syndrome include aging, race, family history, long-term hormone imbalance such as polycystic ovary syndrome (PCOS), gestational diabetes.
Based on the results, researchers concluded, "β-sitosterol could be potentially used to prevent high-fructose diet-induced metabolic dysfunction".
Most people with metabolic syndrome do not experience any symptoms, until the condition progression into a later stage, overtimes, leading to insulin resistance and plagues built-up on the wall of the arteries.
Other risk factors that increased the risk of metabolic syndrome include aging, race, family history, long-term hormone imbalance such as polycystic ovary syndrome (PCOS), gestational diabetes.
Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.
On finding a potential phytochemical for the prevention of cardiovascular diseases and diabetes, researchers investigated the potential protective effect of β-sitosterol against the development of metabolic dysfunction.
The study included 35 21-day-old female Sprague Dawley rat pups randomly allocated to and administered the following treatments: group 1-standard rat chow (SRC) + plain drinking water (PW) + plain gelatine cube (PC); group 2-SRC + 20% w/w fructose solution (FS) as drinking fluid + PC; group 3-SRC + FS + 100 mg/kg fenofibrate in gelatine cubes; group 4-SRC + FS + 20 mg/kg β-sitosterol gelatine cube (Bst); and group 5-SRC + PW + Bst.
According to the results after 12 weeks of feeding,
* The high-fructose diet group showed an increase of visceral adiposity and plasma triglyceride concentration but decreased (P < .05) plasma adiponectin concentration associated with return cholesterol in the blood.
* β-sitosterol treatment prevented the high-fructose diet-induced visceral obesity, hypertriglyceridemia, and hypoadiponectinemia.
* Furthermore, β-sitosterol alone increased plasma adiponectin concentration and reduced plasma insulin concentration and homeostatic model assessment index.
On finding a potential phytochemical for the prevention of cardiovascular diseases and diabetes, researchers investigated the potential protective effect of β-sitosterol against the development of metabolic dysfunction.
The study included 35 21-day-old female Sprague Dawley rat pups randomly allocated to and administered the following treatments: group 1-standard rat chow (SRC) + plain drinking water (PW) + plain gelatine cube (PC); group 2-SRC + 20% w/w fructose solution (FS) as drinking fluid + PC; group 3-SRC + FS + 100 mg/kg fenofibrate in gelatine cubes; group 4-SRC + FS + 20 mg/kg β-sitosterol gelatine cube (Bst); and group 5-SRC + PW + Bst.
According to the results after 12 weeks of feeding,
* The high-fructose diet group showed an increase of visceral adiposity and plasma triglyceride concentration but decreased (P < .05) plasma adiponectin concentration associated with return cholesterol in the blood.
* β-sitosterol treatment prevented the high-fructose diet-induced visceral obesity, hypertriglyceridemia, and hypoadiponectinemia.
* Furthermore, β-sitosterol alone increased plasma adiponectin concentration and reduced plasma insulin concentration and homeostatic model assessment index.
Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of diseases associated with metabolic dysfunction, pending to the confirmation of the larger sample size and multicenter human study.
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) β-Sitosterol Shows Potential to Protect Against the Development of High-Fructose Diet-Induced Metabolic Dysfunction in Female Rats by Gumede NM1, Lembede BW1, Brooksbank RL1, Erlwanger KH1, Chivandi E. (PubMed)
Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) β-Sitosterol Shows Potential to Protect Against the Development of High-Fructose Diet-Induced Metabolic Dysfunction in Female Rats by Gumede NM1, Lembede BW1, Brooksbank RL1, Erlwanger KH1, Chivandi E. (PubMed)
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