Beta-Sitosterol, the Potential Treatment of Atopic Dermatitis

By Kyle J. Norton

Skin, a large organ that forms the out layers of our body has serval layers of ectodermal tissue to protect the underlying muscles, bones, ligaments, and internal organs against foreign pathogenic invasion.

Dermatitis or eczema is a group of diseases characterized by the inflammation of the skin.

There is no single cause of eczema, anything that we face every day can trigger a dermatitis flare, including stress, irritants, climate change, and sweating. However, infection and allergens. are considered the most common causes of the disease.

Atopic dermatitis or eczema is an inflammatory condition associated with red and itchy skin.

Most cases of atopic dermatitis are found in children. However, adults may also get it too.

The causes of atopic dermatitis are unknown. Some researchers suggested that certain risk factors such as genetic preposition and abnormal function of the immune system and environmental conditions may involve in the development of the disease.

Epidemiological studies suggested that most patients with chronic atopic dermatitis also have asthma and hay fever, particularly allergies.

Atopic dermatitis has been found to associate with exposure to allergens such as pollen, pet dander, or peanuts, or by stress, dry skin, and infection.

Some atopic dermatitis may also be triggered by skin irritants such as some fabrics, soaps, and household cleaners.

Beta-Sitosterol is a phytochemical in the class of Phytosterols, belongings to the group of Lipids, found abundantly in avocados, rice bran, wheat germ, corn oils, fennel, peanuts, soybeans, hawthorn, basil, buckwheat. etc.

On finding a potential phytochemical for the prevention and treatment of skin diseases, researchers examined the effect of β-sitosterol (BS) on atopic dermatitis (AD).

In NC/Nga mice induced AD-like skin lesions in NC/Nga by 2,4-dinitrofluorobenzene (DNFB), BS reduced the total clinical severity of AD.

The application of BS inhibited the Infiltration of inflammatory cells and the number of scratching, compared to the DNFB-treated group.

In other words, BS significantly reduced the levels of inflammation-related mRNA and protein and tumor necrosis factor-α from the stimulated splenocytes in the AD skin lesions.

Furthermore, BS significantly also reduced the levels of histamine, IgE, and interleukin-4 associated with skin inflammation n the serum of DNFB-treated NC/Nga mice

Taken altogether, beta-Sitosterol may be considered a supplement for the prevention and treatment of atopic dermatitis, pending the confirmation of the larger sample size and multicenter human study.

Intake of beta-Sitosterol in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) The β-sitosterol attenuates atopic dermatitis-like skin lesions through down-regulation of TSLP by Han NR1, Kim HM, Jeong HJ. (PubMed)