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Tuesday, 20 October 2020

Ashwagandha, the Anti Bacterial Infection Functional Remedy

By Kyle J. Norton

The bacterial infection is the infection caused by bacteria. Most cases of bacterial infection are treated with antibiotics. However, bacteria are very adaptable, overuse of antibiotics has made many of them resistant to antibiotics.

There are trillions of strains of bacteria in the world, but only a few of these cause diseases in humans. Some of them live inside our gut.

The most common symptoms of bacterial infection are redness and heat, swelling, fever, pain at the site of infection.

In severe cases, the patient may also experience symptoms of swollen lymph glands.

Most cases of bacterial infection can be treated successfully if the types of bacteria that cause the infection are identified.

There are a number of risk factors associated with the onset of bacterial infection, some researchers suggested that people with a weakened immune system may increase the prevalence of bacterial infection.

Dr. van Aalst, the lead scientist wrote, "Patients with a weakened immune system due to immunosuppressive treatment are at increased risk of infection with Streptococcus pneumonia".

And, " in patients treated with immunosuppressive medication and compared to controls, the initial serologic response to the pneumococcal conjugate vaccine (PCV) and pneumococcal polysaccharide vaccine (PPSV) is impaired. Moreover, this impaired response was more profound after PCV than after PPSV".

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.

On finding a potent compound for the prevention and treatment of infectious diseases, researchers examined the antibacterial effects of aqueous and alcoholic extracts of the plant (root as well as leaves) against a range of bacteria.

According to the tested differentiation, the methanolic extract sub-fractionated using various solvents and the butanoic sub-fraction showed maximum inhibitory activity against a spectrum of bacteria including Salmonella typhimurium.

The application of both aqueous and alcoholic extracts is considered safe compared to the synthetic antibiotic (viz. chloramphenicol), as these extracts did not induce lysis on incubation with human erythrocytes.

In salmonellosis in Balb/C mice, extracts isolated from plants (both root and leaves) also demonstrated a strong effect on tested salmonellosis.

Finally, researchers said, " Oral administration of the aqueous extracts successfully obliterated salmonella infection in Balb/C mice as revealed by increased survival rate as well as less bacterial load in various vital organs of the treated animals".

Taken altogether, Ashwagandha may be considered a functional herb for the treatment of bacterial infections, pending to the result of larger sample size and multicenter study

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Antibacterial efficacy of Withania somnifera (ashwagandha) an indigenous medicinal plant against experimental murine salmonellosis by Owais M1, Sharad KS, Shehbaz A, Saleemuddin
M. (PubMed)
(2)  The effect of immunosuppressive agents on immunogenicity of pneumococcal vaccination: A systematic review and meta-analysis by van Aalst M1, Langedijk AC1, Spijker R2, de Bree GJ Grobusch MP4, Goorhuis A. (PMC)

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