Herbal Turmeric Protects the Kidneys Against Drugs, Heavy Metals and Substances Toxicity

By Kyle J. Norton


The kidneys are a pair of kidney shape organs located on either side of your spine with a function to filter out the wastes from the blood before passing the wastes through urinary secretion.

More than a detoxed organ, the kidneys also maintain the body fluid balance, regulate the production of red blood cell and high blood pressure.

Kidney damage can be acute such as an overdose of toxin or chronic. Acute kidney diseases can be cured if the underlying cause is found.

Chronic kidney disease (CKD)  is a slow and progressive disease which can lead to kidney failure over time.

At the advanced of CKD can cause the dangerous levels of fluid, electrolytes and wastes build up in the body.

According to statistics, approximately 14 percent of the US general population suffer from CKD. Believe it or not, more than 661,000 Americans have kidney failure. Of these, 468,000 individuals are on dialysis, and roughly 193,000 live with a functioning kidney transplant.

Out of many risk factors associated with CKD, some researchers suggested high blood pressure is one most prevalent risk factor found in most patients.

The Natural Kidney Foundation wrote, "More than half the people with chronic kidney disease (CKD) have high blood pressure. High blood pressure increases the chance that kidney disease will get worse"

And "Following your treatment plan carefully and keeping your blood pressure under control can help to prevent these complications".

Turmeric is a perennial plant in the genus Curcuma, belonging to the family Zingiberaceae, native to tropical South Asia.

The herb has been used in traditional medicine as anti-oxidant, hypoglycemic, colorant, antiseptic, wound healing agent, and to treat flatulence, bloating, and appetite loss, ulcers, eczema, inflammations, etc.

On finding a potential compound with the kidney protective property, researchers investigated curcumin, a major phenolic compound the rhizome of the Curcuma species anti kidney toxicity.

In glucose, tartrazine, induced toxicity, curcumin protected the kidney against DNA damage in leucocytes.

In a streptozotocin-induced diabetes rat model, curcumin protected the kidney against overexpression of free radical to cause kidney cell damage through its antioxidant activity.

In the long term heavy metal model,  curcumin inhibited the toxic effect caused by the accumulation of the metal in the induction of kidney cell damage.

In an animal model induced cisplatin-induced acute kidney injury by injection cisplatin, curcumin enhanced the function of cisplatin-resistant cancer cells and decrease its unwanted side effects.

More interestingly, curcumin inhibited the nicotine receptors on kidney cells that link nicotine to accelerated kidney damage in cigarette smokers

In other words. if the kidneys are less able to excrete nicotine, in long term, accumulated of the extracellular fluid and blood volumes increase, that can lead to severe kidney damage.

In other studies, kidney damage caused maleate, malathion, nicotine, cisplatin, gentamicin, and methotrexate also reversed by the injection of curcumin, similar to those of the aforementioned substances.

Taken altogether, turmeric and its bioactive compound curcumin may be considered remedies the prevention and treatment of kidney damage, pending to the confirmation of the larger sample size and multicenter human study.

Intake of turmeric in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Protective effects of ginger-turmeric rhizomes mixture on joint inflammation, atherogenesis, kidney dysfunction and other complications in a rat model of human rheumatoid arthritis by Ramadan G1, El-Menshawy O. (PubMed)
(2) Protective effects of curcumin against toxic agents-induced renal failure: a review by Farkhondeh T1, Samarghandian S2, Azimi-Nezhad M2, Shahri AMP. (PubMed)
(3) High Blood Pressure and Chronic Kidney Disease by The Natural Kidney Foundation