Scientists may have found a natural aal ingredient used in every kitchen for the treatment of Alzheimer's disease (AD), according to studies.
Alzheimer's disease is a progressive disease caused the gradual loss of the neurons in the affected area.
People with AD experience of symptoms of memory, thinking, and behavior severe enough to affect language communication, memory, lifelong hobbies or social life. The severity of symptoms is totally depending on the stage of the disease.
Without proper treatment, Alzheimer's disease can get worse over time, and it is fatal.
According to the statistic, over 1 million people in the US alone are currently afflicted by Alzheimer's disease caused by the generation of the hippocampus and cerebral cortex of the brain where memory, language, and cognition located.
With this mental disorder, brain cells gradually die and generate fewer and fewer chemical signals day by day, leading to diminished functions.
As of today, there is no known cure. Most treatment is to interfere with the progression and improve the quality of the disease in people in the early stage.
Although there are many risk factor associated with the disease onset. However, in the examination of the median age of patients diagnosed with AD. Some researchers suggested that the increase in age may be one of the major risk factors that cause Alzheimer's disease.
Dr. Raymond Y. Lo, said, "Alzheimer's disease (AD) has become a global health issue as the population ages. There is no effective treatment to protect against its occurrence or progression. Some argue that the lack of treatment response is due to delays in diagnosis. By the time a diagnosis of AD is made, neurodegenerative changes are at the stage where very few neurons can be salvaged by medication".
And, " The paradigm of dementia care policy may shift to early diagnosis of AD pathology and comprehensive care for chronic diseases in the elderly population".
Alzheimer's disease is a progressive disease caused the gradual loss of the neurons in the affected area.
People with AD experience of symptoms of memory, thinking, and behavior severe enough to affect language communication, memory, lifelong hobbies or social life. The severity of symptoms is totally depending on the stage of the disease.
Without proper treatment, Alzheimer's disease can get worse over time, and it is fatal.
According to the statistic, over 1 million people in the US alone are currently afflicted by Alzheimer's disease caused by the generation of the hippocampus and cerebral cortex of the brain where memory, language, and cognition located.
With this mental disorder, brain cells gradually die and generate fewer and fewer chemical signals day by day, leading to diminished functions.
As of today, there is no known cure. Most treatment is to interfere with the progression and improve the quality of the disease in people in the early stage.
Although there are many risk factor associated with the disease onset. However, in the examination of the median age of patients diagnosed with AD. Some researchers suggested that the increase in age may be one of the major risk factors that cause Alzheimer's disease.
Dr. Raymond Y. Lo, said, "Alzheimer's disease (AD) has become a global health issue as the population ages. There is no effective treatment to protect against its occurrence or progression. Some argue that the lack of treatment response is due to delays in diagnosis. By the time a diagnosis of AD is made, neurodegenerative changes are at the stage where very few neurons can be salvaged by medication".
And, " The paradigm of dementia care policy may shift to early diagnosis of AD pathology and comprehensive care for chronic diseases in the elderly population".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of Alzheimer's disease (AD) with no side effects investigated the methanolic extract of dry ginger (GE) anti AD through the antioxidant activity, cholinesterase inhibition, anti-amyloidogenic potential, and neuroprotective properties.
The root has been used in traditional and Chinese medicine for the treatment of dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
Researchers on finding a natural compound for the treatment of Alzheimer's disease (AD) with no side effects investigated the methanolic extract of dry ginger (GE) anti AD through the antioxidant activity, cholinesterase inhibition, anti-amyloidogenic potential, and neuroprotective properties.
The extracts used for the study included18 +/- 0.6 mg/g gallic acid equivalents of total phenolic content and 4.18 +/- 0.69 mg quercetin equivalents/g of dry material.
GE expressed high antioxidant activity with an IC50 value of 70 +/- 0.304 microg/mL, through reducing the expression of neuro oxidative stress in the initiation of AD.
Furthermore, GE effectively prevented the formation of Abeta oligomers and dissociated the preformed oligomers.
Based on the results, Dr. Mathew M, the lead scientist said, "Methanolic GE influences multiple therapeutic molecular targets of AD".
Rat AD models used for the study were treated with a one-time intra-cerebroventricular injection of amyloid β-protein (Aβ) and continuous gavage of aluminum chloride every day for 4 weeks before GRE was administered intragastrically.
At day 35, The significant memory deficits were shorter in the group that received OP with a high dose of GRE (HG)(OP+HG) than in the groups that received OP with a low or moderate dose of GRE (LG, MG)(OP+LG, OP+MG).
High dose of GRE (HG)(OP+HG) injection also increased the expression of antioxidant enzymes produced by the host such as superoxide dismutase (SOD) and catalase (CAT) compared to the OP+HG groups (p<0.05).
Also, rat treated high dose of GRE (HG)(OP+HG) also showed reduced levels of pro-inflammatory cytokines and oxidative stress marker.
Take all together, ginger processed a high amount of bioactive compounds may be considered a function alternative for the prevention and treatment of AD, pending to the confirmation of large sample size and multicenter human study.
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Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) In vitro evaluation of anti-Alzheimer effects of dry ginger (Zingiber officinale Roscoe) extract by Mathew M, Subramanian S. (PubMed)
(1) Protective effects of ginger root extract on Alzheimer disease-induced behavioral dysfunction in rats by Zeng GF1, Zhang ZY, Lu L, Xiao DQ, Zong SH, He JM. (PubMed)
(3) The borderland between normal aging and dementia by Raymond Y. Lo. (PMC)
How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma ISSN 0975-6299.
Sources
(1) In vitro evaluation of anti-Alzheimer effects of dry ginger (Zingiber officinale Roscoe) extract by Mathew M, Subramanian S. (PubMed)
(1) Protective effects of ginger root extract on Alzheimer disease-induced behavioral dysfunction in rats by Zeng GF1, Zhang ZY, Lu L, Xiao DQ, Zong SH, He JM. (PubMed)
(3) The borderland between normal aging and dementia by Raymond Y. Lo. (PMC)
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