Cooked Tomatoes, Protect the Blood Vessels Against the Onset of stroke

By Kyle J. Norton

A stroke is a medical condition caused by poor blood flow to the brain, leading to the death of neurons.

Stroke can be classified into 2 types
* Ischemic stroke is a condition caused by lack of blood flow, and

* Hemorrhagic stroke is a condition caused by bleeding in the brain

Symptoms of stroke are depending on the location which causes cells death. However, both conditions can lead to parts of the brain not functioning properly.

According to the statistics, stroke is the third leading cause of death. Approximate 1/4 of all stroke victims die as a direct result of the stroke or its complications.

Stroke kills about 140,000 Americans each year, accounting to 1 out of every 20 deaths.in the US.

Believe it or not, every year, more than 795,000 people in the United States have a stroke.

Out of numbers of risk factors associated with stroke developing, in the Western world, an uncontrolled diet that is high in saturated and trans fats resulting in cholesterol build up in the arteries and high blood pressure may be one of the major causes.

 In other words, cholesterol and other substances build up in the arteries due to the high-fat diet can induce stroke by blocking the circulation of blood to the brain.

Dr. wrote, "The intake of saturated fatty acids (SFA) and monounsaturated fatty acids (MUFA) both in men and women with stroke were significantly higher than controls (P = 0.04 and P = 0.03 for men and P = 0.05 and P = 0.02 for women, respectively). Also, the mean intake of hydrogenated fats, butter, cream, mayonnaise sauce,.. were higher in men with stroke with respect in control group; while, women with stroke consumed more hydrogenated fats, vegetable oils, cream and mayonnaise sauce than controls".

And, "Increased fat intake was observed in patients with stroke compared with the normal population".

Tomato is red, edible fruit, genus Solanum, belonging to family Solanaceae, native to South America. Because of its health benefits, the tomato is grown worldwide for the commercial purpose
and often in the greenhouse.

On finding a natural ingredient for the prevention of stroke, researchers examined whether serum concentrations of major carotenoids, α-tocopherol, and retinol found in tomato, are related to any stroke and ischemic stroke in men.
The study consisted of 1,031 Finnish men aged 46-65 years in the Kuopio Ischaemic Heart Disease Risk Factor cohort.

Serum concentrations of carotenoids retinol and α-tocopherol were measured according to the high-performance liquid chromatography.

After taking other risk factors into account, researchers found that levels of lycopene process a significantly reduced risk of ischemic stroke and any stroke by 59% and 55% respectively observed by the highest quartile of serum lycopene concentrations compared to men in the lowest quartile.

Interestingly, α-Carotene, β-carotene, α-tocopherol, and retinol were not related to the risk of strokes.

In other words, intake of tomatoes frequently and daily prevent the risk of stroke, particularly in men aged 46-65 years.

In order to obtain more information of tomatoes against the onset of stroke, researcher launched a review of the role of carotenoids as antioxidants in lowering stroke risk based on observational studies.

According to the studies selected from the database published between 2000 and 2017, high dietary intake of six main carotenoids (i.e., lycopene, <- and®-carotene, lutein, zeaxanthin, and astaxanthin) was associated with reduced risk of stroke and other cardiovascular outcomes.

In-depth differentiation of the results, researchers found that multiple mechanisms except antioxidant activity are found to involve in these observed beneficial effects.

Taken altogether, tomatoes processed high amounts of a number of bioactive compounds may be considered supplements for the prevention of stroke, pending to the confirmation of the larger sample size and multicenter human study.

Intake of lycopene in the form of supplement should be taken with extreme care to prevent overdose acute liver toxicity.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Targeting Histone Deacetylases with Natural and Synthetic Agents: An Emerging Anticancer Strategy by Singh AK1, Bishayee A2, Pandey AK. (PubMed)
(2) Lycopene loaded whey protein isolate nanoparticles: An innovative endeavor for enhanced bioavailability of lycopene and anti-cancer activity by Jain A1, Sharma G2, Ghoshal G3, Kesharwani P4, Singh B5, Shivhare US4, Katare OP. (PubMed)

Stroke
(1) Serum lycopene decreases the risk of stroke in men: a population-based follow-up study by Karppi J1, Laukkanen JA, Sivenius J, Ronkainen K, Kurl S. (PubMed)
(2) Carotenoids as Potential Antioxidant Agents in Stroke Prevention: A Systematic Review by Bahonar A1, Saadatnia M1, Khorvash F1, Maracy M2, Khosravi A. (PubMed)
(3) Comparison of fat intake between patients with stroke and normal population by Leila Darvishi,1 Mitra Hariri,1 Maryam Hajishafiei,1 Shekoofe Ghasemi,1 Zahra Maghsoudi,1Gholamreza Askari,1,2 Reza Ghiasvand,1,2 Fariborz khorvash,3 and Bijan Iraj. (PubMed)