Herbal Burdock, The Herb Which Gobbles Up Cancer Cells, in Vitro, Scientists Say

By Kyle J. Norton


Scientists may have a functional herbal medicine for the treatment of cancer without inducing side effects, some studies suggested.

Cancers are a class of chronic diseases associated with the irregular and untrollable cell growth that starts on the surface of the inner lining of organs' tissue caused by some unknown mechanisms that alternate the cell DNA.

At the advanced stage, most malignant cells can travel a distance away from the original site to invade other healthy tissue and organs.

According to the statistic, the most common cancer in the US is breast cancer, every year over 260,000 new cases are diagnosed, causing over 40,000 deaths. The next on the list of most common cancers are lung cancer and prostate cancer.

In Canada, the Canadian Cancer Society statistic showed that 1 in 2 Canadians (49% of men and 45% of women) is expected to develop cancer during their lifetime.

The exact causes of cancer are unknown. researchers do not know the reason why? people with the same health conditions, family history, and race, some are susceptible to the early onset of chronic diseases while others do not.

The genetic preposition that occurs after birth and acquired gene mutation caused by long-term smoking, radiation, viruses, carcinogens, obesity, hormones, chronic inflammation and a lack of exercise.are some of the most prevalent risk factors associated to the increased risk of cancers.

However, most people with many of the above risk factors are cancers free.

In the diet and lifestyle perspective in the risk of cancers, Dr. Harvie M, the lead author in the study" Can diet and lifestyle prevent breast cancer: what is the evidence?" said, "successful lifestyle changes could prevent 25% to 30% of cases of breast cancer. These reductions will only be achieved if we can implement targeted prevention programs for high-risk women and women in population-based breast screening programs during childhood, adolescence, and early adulthood, when the rapidly developing breast is particularly susceptible to carcinogenesis" and "a healthy dietary pattern, does not have specific effects on breast cancer risk but remains important as it reduces the risk for other common diseases".

Burdock is a plant in the group of biennial thistles, genus Arctium, belonging to the family Asteraceae, native to the Euro.

Arctium lappa or burdock has been used as a healthy and nutritive food in Chinese societies and therapeutically in Europe, North America and Asia for hundreds of years.

The herb has been used over thousands of years in traditional Chinese and other traditional herbal medicine as a diuretic, diaphoretic, and a blood purifying agent and to treat wounds and infections stomach ulcers and other digestive problems.

Burdock contains carbonated water, sugar,, manloid colorings, phosphoric acid, citric acid and a good amount of dietary fiber, calcium, potassium, and amino acids and chemicals compounds of guaianolide, arctinone, arctinal, methyl arctate，11-tridecadien-3，5，7，9-tetraynde-hydrocostus lactone，dehydrodihydrocostus lactone, 3-octanoic acid, 3-hexenoic acid etc.

In the searching of new cancer-fighting therapeutics without inducing adverse effects, scientists at the State University of New York, launched an investigation to examine the anti-cancer effects of a novel anticancer constituent, Lappaol F, from herbal Burdock plant.

In human cancer cell lines of various tissue types, Lappaol F induced G(1) and G(2) cell-cycle arrest, which was associated with strong induction of p21 and p27 which process a strongly apoptotic activity and reduction of cyclin B1 and cyclin-dependent kinase 1 (CDK1) in promoting cancer cellular proliferative survival activity.

Furthermore, application of Lappaol F was found to induce cell death in several cancer cell lines and to activate caspases that program cells death.

The application also exerted a significant cytotoxic activity against tumor cells without harming the healthy nearby cells.

Lappaol F was well tolerated with no significant toxicity.

Dr. Sun Q, the final report said, "our results, for the first time, demonstrate that Lappaol F exhibits antitumor activity in vitro and in vivo and has strong potential to be developed as an anticancer therapeutic".

Moreover, the study evaluated the cytotoxicity profiles of 364 herbal plant extracts, using various cancer and normal cell lines, researchers showed that arctigenin as tumor-specific agent found in Burdock showed a strong cytotoxicity to lung cancer (A549), liver cancer (HepG2) and stomach cancer (KATO III) cells, without harming to several normal cell lines.

Arctigenin specifically inhibited the proliferation of cancer cells, which might consequently lead to the induction of apoptosis.

Taken all together, herbal Burdock processed bioactive compounds Lappaol F and Arctigenin may be considered a functional herb for the prevention and combined with primary therapy for the treatment of cancers.

However, due to the limitation of the above studies, additional data collection large example size and multi-centers studies performed with human consumption of the whole food or its bioactive compounds during the course of the disease will be necessary to complete the picture of herbal anti cancers possibility.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

References
(1) Lappaol F, a Novel Anticancer Agent Isolated from Plant Arctium Lappa L by Sun Q, Liu K, Shen X, Jin W, Jiang L, Sheikh MS, Hu Y, Huang Y. (PubMed)
(2) Tumor-specific cytotoxicity of arctigenin isolated from herbal plant Arctium lappa L by Susanti S, Iwasaki H, Itokazu Y, Nago M, Taira N, Saitoh S, Oku H.(PubMed)
(3) Can diet and lifestyle prevent breast cancer: what is the evidence? by Harvie M1, Howell A1, Evans DG. (PubMed)