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Monday, 23 July 2018

Infectious Diseases Caused By Over Growth of Candida - The Anti Intestinal Dysbiosis Therapies

By Kyle J. Norton, Scholar, Master of Nutrition

Candida albicans are members of a large group of micro organism whose cells contain complex structures enclosed within the membranes, including yeast(2)(3), fungi(4)(5)(6), and mold(6) that live among the gut flora in the human mouth and gastrointestinal tract.

Non-albicans Candida (NAC) species cause 35-65% of all candidaemias in the general patient population(1).

Dysbiosis is medical condition in the gastrointestinal tract, caused by either intestinal bacterial overgrowth (SIBO) or small intestinal fungal overgrowth.

Some researchers suggested, " dysbiosis may not be the most important factor, rather the products of interaction between diet and the microbiome and "High-protein diets are thought to result in the production of carcinogenic metabolites from the colonic microbiota that may result in the induction of neoplasia in the colonic epithelium"(1).

Dr. Sara Gottfried MD in the article of " Dysbiosis Decoded: Symptoms, Why You Get It, and Link to Autoimmunity, Breast Cancer, Irritable Bowel Syndrome, Plus Other Common Conditions" suggested that if you experience 5 of below symptoms, you may be infected by intestinal fungal overgrowth dysbiosis(a).

Here is the list provided by the doctor(a)
* Frequent gas or bloating on most days of the week
* Cramping, urgency, and/or mucus in your poop once per week
* Brain fog, anxiety, or depression
* Food sensitivities
* Missing micronutrients
* Chronic bad breath
* Loose stool, diarrhea, constipation, or a combination
* Diagnosis of Irritable Bowel Syndrome (IBS)
* History of “stomach bugs,” gastroenteritis, and/or food poisoning
* History of prolonged antibiotics such as for acne or sinusitis
* Carbohydrate intolerance, particularly after eating fiber and/or beans
* Fatigue or low energy
* Use of anti-acids for heartburn, reflux, or hiatal hernia?
* Autoimmunity, or an autoimmune condition such as Hashimoto’s thyroiditis, psoriasis, or multiple sclerosis
* Sinus congestion


The Therapies that Inhibit Intestinal Dysbiosis Caused by Over Growth of Candida
1. Probiotics
Probiotics are live micro-organisms conferred a health benefit on the host and found to be benefits the digestive system(363), including inflammatory bowel disease(364).

According to Dalian Medical University, there are many causes of dysbbiosis, such as prolonged period intake of antibiotic used widely in conventional medicine for treatment of bacterial infection(365).

Dr. McFarland LV at the University of Washington said that the use of probiotics to restore the balance of undisturbed microbiota in healthy individual is most effectively than patients with postdisruptive event and probiotic therapy and pre-existing disrupted microbiota and then postprobiotic therapy(366).

2. Prebiotics
Prebiotic, the non-digestible food ingredients and the most prevalent forms of prebiotic is nutritionally classed soluble fiber(367), including Galactooligosaccharide, stimulated the production of number and/or activity of bifidobacteria and lactic acid bacteria(368) and/or activity in the digestive system(369) in ways claimed to be beneficial to health of the host, by counteracting to the overgrowth of bad bacteria(371)(372), including candida albicans.


3. High fiber foods
Fiber is the indigestible portion of plant foods having two main components soluble and insoluble fiber, consisted non-starch polysaccharides such as arabinoxylans( woods and cereal grains), cellulose(a linear chain of several hundred to many thousands of linked D-glucose unit) and many other plant component.

While it is beneficial for alleviating symptoms of irritable bowel syndrome(373), such as diarrhea and/or constipation and abdominal discomfort, it is also a prebiotic(374) which is beneficial to health of the host by enhancing the production of good bacteria in the gastrointestinal tract(375) and counteracting to the overgrowth of bad bacteria, including candida albicans.

4. Avoid allergic foods
Eating allergic foods often causes symptoms of digestive disorders(376), including gas, stomach pains, diarrhea, constipation, bloating, etc. as allergen-producing L. lactis strains(377) induced imbalance of bacteria in digestive systems, that can lead to overgrowth of bad bacteria quickly.

5. Regular intake of Allium satvum (garlic)
Allium satvum is a species in the onion family Alliaceae, native to Central Asia.

Garlic beside is best known for its effectiveness in treating hypertension(378), hyper cholesterol(379), blood thinner(380) and cancer(381), it also contains high amount of phytoncides that inhibits the growth of microorganisms(382) and phytoalexin called allicin which processes anti-oxidative(383)(384) and anti-microbial effects(385).

The herb would be helpful to keep a healthy digestive system and prevent the growth out of control of bad bacteria.

6. Enhances immune system
Living healthy and eating healthy foods such as such as whole grain, fresh fruits, vegetables, nuts and seeds, beans and legumes provide your body with necessary nutrients, including antioxidants, vitamins and minerals, that not only optimizes the digestive absorption but also enhances the immune system(386)(387)in fighting against inflammation(389) and infection(388) caused by virus and bacteria.

7. UVC therapy
Light therapy is considered as a type of treatment of exposing to daylight or to specific wavelengths of light, used to accelerate wound healing(390), hair growth, and improved blood properties(391).

Statistical analysis found in vitro candida strains were sensitive to UVC(392) and photodynamic therapy with malachite green(393).

8. Exercise
Exercise is important in enhancing the immune system(394) to reduce the likelihood of getting yeast infections(385) but also put your body in a better position to fight off the candida.

9. Reduce stress
Signs of stress may be cognitive, emotional, physical or behavioral, signs of poor judgment, a general negative outlook, can depress the immune system(395) and impair the digestive system(396), causing psoriasis(397), a chronic autoimmune disease and gastrointestinal tract infection(396), leading to more favorable conditions for unhealthy candida to multiple.


10. Specific sexual practices and sexual behavior
A study in USA revealed that a 75% percentage of women have had candida yeast overgrowth at some points in their lives in comparison to only 45% of men. Sexual practices such as receptive anal and oral sex and douching increase the risk of infectious candida(398).

Risk of vulvovaginal candidiasis also increases in women who have sex with several women partners(399)(400). If you noticed changes in your body such as thick, cheese-like discharges, pain during sex and an itchy burning sensation, check with your doctor immediately.



Sources

(a) Dysbiosis Decoded: Symptoms, Why You Get It, and Link to Autoimmunity, Breast Cancer, Irritable Bowel Syndrome, Plus Other Common Conditions By Sara Gottfried MD
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(5) Mechanisms of resistance to azole antifungal agents in Candida albicans isolates from AIDS patients involve specific multidrug transporters.by Sanglard D1, Kuchler K, Ischer F, Pagani JL, Monod M, Bille J.(PubMed)
(6) Structural analysis of phospho-D-mannan-protein complexes isolated from yeast and mold form cells of Candida albicans NIH A-207 serotype A strain by Shibata N1, Fukasawa S, Kobayashi H, Tojo M, Yonezu T, Ambo A, Ohkubo Y, Suzuki S.(PubMed)
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(366) Use of probiotics to correct dysbiosis of normal microbiota following disease or disruptive events: a systematic review by McFarland LV1(PubMed)
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(384) Aged garlic extract and its constituents inhibit Cu(2+)-induced oxidative modification of low density lipoprotein by Ide N, Nelson AB, Lau BH.(PubMed)
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