Food Therapy: Coffee and Coffee Caffeine in Reduced Risk and Treatment of impaired fasting glucose

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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In take of coffee and coffee caffeine daily and regularly is associated to reduced risk and treatment of abnormal fasting glucose levels, epidemiological studies suggested.

Impaired fasting glucose is a condition characterized by abnormal high blood glucose after meal and considered as an indication of prediabetes or symptoms of diabetics.

Coffee, a popular and social beverage all over the world, particularly in the West, is a drink made from roasted bean from the Coffea plant, native to tropical Africa and Madagascar.

In a prospective study, 910 adults aged >/=50 years without diabetes at baseline in 1984-1987 followed to 1992-1996, an average of 8 years after assessment of coffee intake, researchers found that
past and current coffee drinkers not only had a reduced risk of incident diabetes but also improved impaired glucose in compared with those who never drank coffee.

In 317 participants who are past or current coffee drinkers showed a significant reduced level of fasting blood glucose in compared to the baseline.

Based on an oral glucose tolerance test (OGTT), Dr. Smith B, the lead author said, "This study confirms a striking protective effect of caffeinated coffee against incident diabetes".

Interestingly, in a study comprised 7949 healthy Swedish subjects aged 35-56 years residing within five municipalities of Stockholm. An oral glucose tolerance test identified 55 men and 52 women with previously undiagnosed type 2 diabetes and 172 men and 167 women with impaired glucose tolerance, researchers at the Karolinska Institutet,file the following results

1. The relative risks when drinking >/=5 cups of coffee per day compared with </=2 cups per day in men were 0.45 and 0.63, respectively, and after adjustment of type 2 diabetes and impaired glucose tolerance but in women, the relative risk was reduced substantially to  0.27.

2. Coffee and coffee caffeine intake was associated inversely in patients with type 2 diabetes.
3. Women, but not in men, with impaired glucose tolerance also benefit from improvement of beta-cell function
4. Both gender with normal glucose tolerance, coffee consumption also displayed a strong effect in reduced risk of insulin resistance.

Dr. Agardh EE, the led author said, "high consumers of coffee have a reduced risk of type 2 diabetes and impaired glucose tolerance. The beneficial effects may involve both improved insulin sensitivity and enhanced insulin response".

Additionally, in a study of subsample of subjects aged 45 to 64 years in 1987 and in 1992 from the population-based FINRISK study (12,287 individuals) invited to receive the standard oral glucose tolerance test at baseline, the fasting and two-hour plasma glucose and insulin measured in 2434 subjects, researchers postulated that according to the data, coffee demonstrated a significantly and inversely associated with fasting glucose, two-hour plasma glucose, and fasting insulin in both men and women.

In fact, intake of coffee in the sample also showed a profound effect in ameliorated impaired fasting glucose, improved impaired glucose regulation, and hyperinsulinemia in both gender, particularly in several glycemia markers.

Conclusively, Coffee, not only is a source of chemical compounds such as chlorogenic acids and lignans in improved glucose metabolism,but also may be considered as a novel mechanisms for effects of diet on  Reduced Risk and Treatment of impaired fasting glucose  and prevent the development of type 2 diabetes.

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Sources
(1) Coffee consumption, type 2 diabetes and impaired glucose tolerance in Swedish men and women by Agardh EE1, Carlsson S, Ahlbom A, Efendic S, Grill V, Hammar N, Hilding A, Ostenson CG.(PubMed)
(2) Effects of coffee consumption on glucose tolerance, serum glucose and insulin levels--a cross-sectional analysis by Bidel S1, Hu G, Sundvall J, Kaprio J, Tuomilehto J.(PubMed)
(3) Coffee and type 2 diabetes: from beans to beta-cells by van Dam RM1.(PubMed)