Food Therapy: Asparagus, the Anti Inflammatory Natural Whole Food

Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Whole food(herbal medicine) used as medical treatment,  linking health benefits in prevention, management and treatment of diseases has induced much interests in today renowned scientists.
But many researchers have raised question of herbal quality, because geographic differences, time of grown and harvest, etc. may effect their's potency. I do believe, these questions can only be answered by experience herbalists.

Asparagus is a flowering plant belong to species the genus Asparagus, native to the western coasts of northern Spain, north to Ireland, Great Britain, and northwest Germany, northern Africa and western Asia, used from early times as a vegetable and medicine, because of its delicate flavour and diuretic properties.

Asparagus may be next potential whole food medicine in inhibited expression of pro inflammatory cytokins in inducing fever, pain and swollen in affect location,....

Inflammation is a natural expression by immune system in induction of while blood cells for protection our body against infection with foreign invasion.

According to the Korea Institute of Oriental Medicine, in an investigation of chronic skin inflammation, using 12-O-tetradecanoyl-phorbol-13-acetate (TPA)-induced mouse ear edema, administration at 200mg/kg (i.p.) of ethanolic extract from Asparagus cochinchinensis Merrill (ACE)expressed strong anti inflammatory effect through inhibited topical edema in the mouse ear, and substantial reductions in skin thickness and tissue weight, inflammatory cytokine production,.....

Dr. Lee DY, the lead author in the study said, "ACE is an effective anti-inflammatory agent in murine phorbol ester-induced dermatitis" and " the compound may have therapeutic potential in a variety of immune-related cutaneous diseases."

The study of pharmacological properties of Asparagus racemosus root extracts (AR), also addressed  the potential used of extract formulation for topical and/or transdermal drug to provide anti-inflammatory activity, due to its significant attenuation involved in systemic inflammation, without causing toxicity to experiment monocytic leukemia cell line THP-1.

Furthermore, the extract from asparagus also exert an inhibitory effect on pro-inflammatory cytokines, namely interleukin 1β and tumour necrosis factor α, and on the production of nitric oxide in free radical-mediated lipid oxidation stimulated by lipopolysaccharide in regualed immune response in vitro.

Some researchers insisted the properties of anti inflammation of asparagus may also due to the presence of phytochemical saponin contents in comparison to group treated with crude saponin extracts in the rat paw-oedema and the control group.

Taking altogether, Asparagus may have a potential anti inflammatory effect in reduced risk and treatment od chronic inflammatory diseases. The efficacy is not due to single ingredient in the food but the whole food.

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Sources
(1) Anti-inflammatory effects of Asparagus cochinchinensis extract in acute and chronic cutaneous inflammation by Lee DY1, Choo BK, Yoon T, Cheon MS, Lee HW, Lee AY, Kim HK.(PubMed)
(2) Anti-inflammatory activity of liposomes of Asparagus racemosus root extracts prepared by various methods by Plangsombat N1, Rungsardthong K2, Kongkaneramit L3, Waranuch N4, Sarisuta N5.(PubMed)
(3) Effects of Chlorophytum arundinaceum, Asparagus adscendens and Asparagusracemosus on pro-inflammatory cytokine and corticosterone levels produced by stress by Kanwar AS1, Bhutani KK.(PubMed)
(4) Anti-inflammatory activity of crude saponin extracts from five Nigerian medicinal plants by Hassan HS1, Sule MI, Musa AM, Musa KY, Abubakar MS, Hassan AS.(PubMed)