Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - The Top immune enhancers - Vitamin B6

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

The Top immune enhancers

Enhancing immunity has shown to reduced risk of inflammatory diseases(218). The University of Calgary study insisted "Uric acid crystals [monosodium urate (MSU)] have emerged as an important factor for both gouty arthritis and immune regulation. This simple crystalline structure appears to activate innate host defense mechanisms in multiple ways and triggers robust inflammation and immune activation"(219)

5. Vitamin B6

Vitamin B6 is water soluble and a member of vitamin B complex, played an important role in amino acids metabolism for to maintaining the proper function in our body. Vitamin B6 deficiency may be associated to risk of hyperglycaemia and hyperuricaemia(231). In deed, according to the  Universidad Complutense de Madrid, consumption of Cereals, vegetables, legumes and fruit, together with milk and eggs, constituted the most important ingredients of the diet in a closed community showed to reduced risk of deficiencies of iron, magnesium, zinc, vitamin B(6) and vitamin D in induction of hyperuricaemia, the main cause of gout(232).


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References

(218) Immunity, inflammation, and cancer by Grivennikov SI1, Greten FR, Karin M.(PubMed)

(219) Monosodium urate crystals in inflammation and immunity by Shi Y1, Mucsi AD, Ng G.(PubMed)

(231) Anthropometry, lipid- and vitamin status of 215 health-conscious Thai elderly by Pongpaew P1, Tungtrongchitr R, Lertchavanakul A, Vudhivai N, Supawan V, Vudhikes S, Prayurahong B, Tawprasert S, Kwanbunjan K, Migasena P, et al.(PubMed)
(232) Nutritional assessment, health markers and lipoprotein profile in postmenopausal women belonging to a closed community by Sánchez-Muniz FJ1, Carbajal A, Ródenas S, Méndez MT, Bastida S, Raposo R, Ruiz T.(PubMed)