Most Common Disease of50plus: The Clinical trials and Studies of Musculo-Skeletal disorders(MSDs)- Gout - Treatment In TCM formula Modified Simiao Decoction

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

              

                                              Treatments

B. Other research and studied formulas

Kyle J. Norton (Scholar and Master of Nutrients, all right reserved)Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Musculoskeletal disorders (MSDs) are medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(*).

Types of Musculo-Skeletal disorders in elder

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                          Gout

Gout mostly effected one joint is an acute and recurrent condition of arthritis as a result of uric acid building up in blood, inducing joint inflammation.

              

                                              Treatments

B. Other research and studied formulas

3. Modified Simiao Decoction

Modified Simiao Decoction(MSD), containing 4 herbs is also one of common used formula in traditional Cjinese medicine for treatment of gouty arthritis. According to the Huazhong University of Science and Technology, the formula attenuated successfully the accumulation of monosodium urate (MSU) crystals in the joints(289), through expression of crystals-induced inflammation through its target of reduced over reaction of proinflammatory cytokines, such as of IL-1 β and TNF α secretion(288).

Dr. Hua J and colleagues at the The Second People Hospital of Xihu District said, "MSD processes uricosuric and nephroprotective actions by regulating renal urate transporters and enhancing antioxidant enzymes activities to improve renal dysfunction in hyperuricemic mice"(290).

In fact, in the review of  a total of 120 cases of gouty arthritis randomly divided into the treatment group and control group with 60 cases in each group study, researchers indicated the effectiveness of the decoction in treatment of gout as the formula significantly improved the symptoms and signs of gouty arthritis and decrease the levels of UA and CRP(291).

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References

(288) Effects of Modified Simiao Decoction on IL-1 β and TNF α Secretion in Monocytic THP-1 Cells with Monosodium Urate Crystals-Induced Inflammation by Liu YF1, Tu SH1, Chen Z1, Wang Y1, Hu YH1, Dong H1.(PubMed)

(289) Monosodium urate crystals trigger Nrf2- and heme oxygenase-1-dependent inflammation in THP-1 cells by Jhang JJ1, Cheng YT1, Ho CY1, Yen GC2.(PubMed)

(290) Anti-hyperuricemic and nephroprotective effects of Modified Simiao Decoction in hyperuricemic mice by Hua J1, Huang P, Zhu CM, Yuan X, Yu CH.(PubMed)

(291) Treatment of 60 cases of gouty arthritis with modified Simiao Tang by Qiu R1, Shen R, Lin D, Chen Y, Ye H.(PubMed)