Most Common Diseases of elder: The Clinical Trials and Studies of Musculo-Skeletal disorders: Osteoporosis: The effectiveness of Oilve oil, according herbal and TCM medicine specialist

Kyle J. Norton (Scholar)

Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.
Musculoskeletal disorders (MSDs) are  medical condition mostly caused by work related occupations and working environment, affecting patients’ muscles, joints, tendons, ligaments and nerves and developing over time. According to a community sample of 73 females and 32 males aged 85 and over underwent a standardised examination at home, musculoskeletal pain was reported by 57% of those interviewed(1).

      Types of Musculo-Skeletal disorders in elder(2)

1. Osteoarthritis
2. Gout
3. Rheumatoid Arthritis
4. Polymalagia Arthritis
5. Cervical myleopathy and spinal canal stenosis
6. Osteoporosis
7. Low back pain
8. Fibromyalgia

                                Osteoporosis

Osteoporosis is defined as a condition of thinning of bone and bone tissues as a result of the loss of bone density over a long period of time. It is a widespread degenerative disease of skeletal joints and often associated with senescence in vertebrates due to excessive or abnormal mechanical loading of weight-bearing joints, arising from heavy long-term use or specific injuries(6).

                               The Treatment

B. In herbal  and traditional Chinese medicine perspective

3. Nuts and seeds Olive
Olive is belongs to the the family Oleaceae, native to the coastal areas of the eastern Mediterranean Basin and south end of the Caspian Sea. Its fruit, is also called the olive and the source of olive oil.

Olive Oil: Fat Content
1. Saturated fats
a. Palmitic acid
b. Stearic acid
c. Arachidic acid
d. ehenic acid
e. Myristic acid
f. Lignoceric acid
2. Unsaturated fat3. Monounsaturated fats
a. Oleic acid
b. Palmitoleic acid
3. Polyunsaturated fats
a. Linoleic acid
b. Linolenic acid

Monounsaturated fatty acids found abundantly in olive oil, has found to regulate adipose tissue inflammation by altering adipocyte signalling pathways and the secretion of proinflammatory cytokines(422) of that may induced risk of osteoporosis as mentioned.

The richest source of oleoyl serin of olive oil may contribute to lowered prevalence of osteoporosis if consumed in high amount, Dr Bradshaw HB and Leishman E. suggested(423).

In vertebra and tibia in ovariectomized rats, black olive hydroalcoholic extract effectively lower the quantitative changes of the bone structure and prevented bone loss in this osteoporosis animal model, through decreased osteoclast cells in vertebra and tibia(424) and increased in the cortical bone thickness (CBT) and the trabecular bone thickness (TBT)(425).

In deed, according to the study by the Xiamen University, the effectiveness of olive oil in exhibition of anti-osteoporosis is due to its function in significantly increased BMD and decreased phosphatase, alkaline phosphatase, IL-6, MDA, and nitrate levels(426).

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies


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References
(1) Prevalence of rheumatic symptoms, rheumatoid arthritis, ankylosing spondylitis, and gout in Shanghai, China: a COPCORD study by Dai SM1, Han XH, Zhao DB, Shi YQ, Liu Y, Meng JM.(PubMed)
(2) Musculoskeletal Disorders in the Elderly by Ramon Gheno, Juan M. Cepparo, Cristina E. Rosca,1 and Anne Cotten(PMC)
(3) Osteoporosis(Life extension)
(4) Hormone and bone by Francisco Bandeira1, Marise Lazaretti-Castro2, John P. Bilezikian3
(5) Growth hormone and bone by Ohlsson C1, Bengtsson BA, Isaksson OG, Andreassen TT, Slootweg MC.(PubMed)

(6) GH and bone--experimental and clinical studies by Isaksson OG1, Ohlsson C, Bengtsson BA, Johannsson G.(PubMed)

(422) SCD1 mediates the influence of exogenous saturated and monounsaturated fatty acids in adipocytes: Effects on cellular stress, inflammatory markers and fatty acid elongation by Ralston JC1, Metherel AH2, Stark KD3, Mutch DM4.(PubMed)

(423) Levels of bioactive lipids in cooking oils: olive oil is the richest source of oleoyl serine by Bradshaw HB, Leishman E.(PubMed)

(424) Stereological study of the effect of black olive hydroalcoholic extract on osteoporosis in vertebra and tibia in ovariectomized rats by Noorafshan A1, Dabbaghmanesh MH, Tanideh N, Koohpeyma F, Rasooli R, Hajihoseini M, Bakhshayeshkaram M, Hosseinabadi OK.(PubMed)

(425) Olive oil effectively mitigates ovariectomy-induced osteoporosis in rats by Saleh NK1, Saleh HA.(PubMed)

(426) Olive oil in the prevention and treatment of osteoporosis after artificial menopause by Liu H1, Huang H1, Li B1, Wu D1, Wang F1, Zheng Xh1, Chen Q1, Wu B1, Fan X1.(PubMed)