The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: TCM Herbal Medicine for Kidney Yang deficiency - Fu Ling

By Kyle J. Norton
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Polycystic Ovarian Syndrome
Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cancer(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women. Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).

In Traditional Chinese Perspective
While conventional medicine focus of using synthetic medication to induce ovulation and assisted artificial insemination for infertility couple, if the medicine fail, traditional Chinese medicine views polycystic ovarian syndrome in different approaches. Polycystic ovary syndrome, according to traditional Chinese medicine is a medical condition characterized by accumulative of fluid over a prolonged period of time causes of dampness and phlegms(1247a)(1247b) build up on the ovaries due to the effects of vary differentiations, affecting not only the women’s menstrual cycle, but also ovulation and fertility(1247a)(1247b).

PCOs Treatment according traditional Chinese medicine
Depending to differentiation, most common diagnosis of polycystic ovary syndrome can be classified into

Kidney yang deficiency

Along with common symptoms mentioned above, women with PCOs diagnosed with kidney yang deficiency may also experience yang vacuity induced cold expressive syndrome, including lumbago, cold limbs, fatigue, cold aversion, feverish sensation in chest, palms and soles(1573), difficulty in urination, enuresis, incontinence, declining libido and edema(1574) as a result of kidneys no longer perform their function in store fluid to moister and warm the body for healthy function in the body's organs and tissues, inducing adrenal insufficient chronic lower back pain(1575)(1580), depression(1575), hypothyroidism(1579)(1575), nephritis(1578)(1575), ...(1575), leading to failure in transform damp heat expression, promoted accentuation of inflammatory development of phlegm(1583). Kidney yang deficiency has shown to alter carbohydrate and lipid metabolisms (free fatty acids, 1-monolinoleoylglycerol, and cholesterol), gut microbiota metabolism (indole-3-propionic acid), indued anovulatory infertility( 1581) and hypertension(1582) of which related to symptoms of PCOs(1576)(1577).

Herbal medicine for kidney yang deficiency


2. Poria cocos
Poria cocos also known as fu ling, the sweet, bland, neutral herbal medicine has been used in TCM for treatment of cancer(1709)(1710), headache(1712), dizziness(1714), palpitations(1711), insomnia(1715)(1716),  neurodegenerative disease(1717)(1718), chronic gastritis(1714), chronic inflammation(1712) and to strengthen the body(1711), improve body weight(1719), kidney functions(1712)(1713) and protect against lipid peroxidation of red blood cells(1720), etc.... by enhancing the functions of heart, spleen, lung, kidney channels(1711).

Chemical constituents(1711)
1. Pachymose
2. B-pachyman,
3. B-pachymanase
4. Pachymic acid
5. Tumulosic acid
6. Eburioic acid
7. Pinicolic acid
8. β-amprin acetate
9. B-hydroxy lanosta-7
10. Poricoic acid
 11. Caprylic acid
12. Undecanoic acid
13. Lauric acid
14. Dodecenoic acid
15. Palmitic acid
16. Etc.

Epidemiological studies also suggested that poria cocos may be used for treatment of women with PCOs due to its effects on prevented and alleviated dehydroepiandrosterone-induced polycystic ovarian syndrom(1721), decreased serum follicle-stimulating hormone (FSH)(1719) and luteinizing hormone (LH)(1719) levels, weigh gain(1719) through up-regulation of estrogen receptor α (ERα) and estrogen receptor β (ERβ)(1719), improved metabolism(1722), reduced risk of PCOs' complications of diabetes(1723).

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O1.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF1, Li XL, Fang F, Du MR.(PubMed)
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(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB1, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA1, Arduc A2, Tuna MM1, Karakılıc E1, Dagdelen I1, Tutuncu Y1, Berker D1, Guler S1.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO1.(PubMed)
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(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J1, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
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(17) Metabolic Evidence of Diminished Lipid Oxidation in Women WithPolycystic Ovary Syndrome. by Whigham LD1, Butz DE2, Dashti H3, Tonelli M3, Johnson LK1, Cook ME2, Porter WP4, Eghbalnia HR5, Markley JL6, Lindheim SR7, Schoeller DA8, Abbott DH9, Assadi-Porter FM10.(PubMed)
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(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E1.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E1, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
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(1247a) A Comprehensive Treatment of Polycystic Ovarian Syndrome (PCOS) by Liqin Zhao
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(1574) Understanding Kidney Yin and Kidney Yang(Shen-Nong shi)
(1575) Kidney Yang Deficiency: Use Warming Foods and Moxibustion By Jody Smith(Empow her)
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[Article in Chinese] by Wu F, Zhang PQ, Wang XQ, Nie LF, Fu XJ, Peng W, Wang Y, Li J, Bi YP, Mi XH, Ding XQ, He LQ.(PubMed)
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(1709) Pachymic Acid Inhibits Growth and Induces Apoptosis of Pancreatic Cancer In Vitro and In Vivo by Targeting ER Stress by Cheng S¹, Swanson K¹, Eliaz I², McClintick JN³, Sandusky GE⁴, Sliva D⁵.(PubMed)
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(1711) Fu ling(Complementary and Alternative Healing University)
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(1714) Effects of triterpenoids from Poria cocos Wolf on the serotonin type 3A receptor-mediated ion current in Xenopus oocytes by Lee JH¹, Lee YJ, Shin JK, Nam JW, Nah SY, Kim SH, Jeong JH, Kim Y, Shin M, Hong M, Seo EK, Bae H.(PubMed)
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(1723) Anti-Hyperglycemic Properties of Crude Extract and Triterpenes from Poria cocos by Li TH¹, Hou CC, Chang CL, Yang WC.(PubMed)