The Holistic prevention, management and treatment of Polycystic Ovarian Syndrome: The macro nutrients and Glycemic index

By Kyle J. Norton Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
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Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.


                                         Polycystic Ovarian Syndrome

Polycystic Ovarian Syndrome is defined as endocrinologic diseases among reproductive-age women caused by undeveloped follicles clumping on the ovaries that interferes with the function of the normal ovaries associated with a high risk for metabolic disorder(1) as resulting of enlarged ovaries(2), leading to hormone imbalance(excessive androgen and anti-müllerian hormone (AMH) )(1)(3)(4)(5), induced Hirsutism(6)(7), reproductive disorder(10(12)), risks of type 2 diabetes(9)(10)(11), metabolic syndrome(10)(12) and early cardiovasular disease(8)(13), acne(10)(14), endometrial cance(18)(19),weight gain and obesity(15)(16)(17). The syndrome effects over 5% of women population or 1 in 20 women.
Unfortunately, according to studies, women with PCOs after the reproductive age, are associated to  continuously increase risk of type II diabetes, with no increasing altered glucose tolerance(20), CVD and hypertension(21).

                   In Weight Loss Perspective
                                                               


 Weight loss(733)(734) for obese patients is one of most vital factor to reduce PCOs symptoms(735)(737) and risk of PCOs complications(736)(737). Some researchers found that 5-10% of weight low will improve PCOs features(737) by 25%, including pregnancy(738). How can you lose weight and maintain healthy body for a healthy conception?

                                           The macro nutrients

1. Carbohydrate
Carbohydrate is simple sugar and complex sugar found abundantly in food, such as fruits, veggies, breads, cereals, and other grains.....with major function in production of energy for nourish cells, tissues and organs, through converting to blood sugar by digestive system(739).
a) Simple sugar
It contains food with no more than 2 simple sugar connected together. It can be release quickly into your bloodstream(740)(741).
b) Complex sugar
It contains food with long chain of simple sugar connected together, because most of them contain high amount of fiber. Foods will be digested slowly and sugars are released slowly into your bloodstream(740)(741).

2. Protein
Protein is important in building our body tissues. Its function is to carry out most of the reactions involved in metabolism and DNA replication, DNA repair, and transcription(742), therefore, it is important element in preparing for the growth of the bady once you are pregnant(743). Dr. Kramer MS1 and Kakuma R. at the McGill University said "Balanced energy/protein supplementation improves fetal growth and may reduce the risk of fetal and neonatal death. High-protein or balanced protein supplementation alone is not beneficial and may be harmful to the infant. Protein/energy restriction of pregnant women who are overweight or exhibit high weight gain is unlikely to be beneficial and may be harmful to the infant"(744).

3. Fat
Fat is essential for digestive system in absorbing several types of vitamins, maintaining healthy skin, hair, body temperature and healthy cells growth(746), stored as energy through its component of glycerol and expression and activity of the lipases of adipose tissue(745). Not all fats are bad(747)(748), by choosing more good fat and limited intake of the bad one, you are ensure yourself for a healthy pregnancy. Fats include saturated fat, transfat, monosaturated fat and polyunsaturated fat(749).


                                     The Glycemic index?
Glycemic index is a guide or table which rates all carbohydrates according to how fast they release glucose into the blood stream. The fastest release one has a high GI index. Preferences for only taking  foods with low GI index, if you want to lose weight(751)(750), but following low-GI dietary prescription is difficult(750)
                             

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months   
 
References
(1) Adiposity and metabolic dysfunction in polycystic ovary syndrome by Sam S.(PubMed)
(2) A "kiss" before conception: triggering ovulation with kisspeptin-54 may improve IVF by Young SL.(PubMed)
(3.) Androgen hyperfunction and excessive heterosexual hair growth in women, with special attention to the polycystic ovarian syndrome by Lunde O¹.(PubMed)
(4) Expression of anti-Müllerian hormone in letrozole rat model of polycystic ovary syndrome by Du DF¹, Li XL, Fang F, Du MR.(PubMed)
(5) [Serum levels of anti-muller hormone in women with polycystic ovary syndrome and healthy women of reproductive age].[Article in Bulgarian] by Parahuleva N, Pehlivanov B, Orbecova M, Deneva T, Uchikova E.(PubMed)
(6) [Current opinions on the etiology and pathophysiology of hirsutism].[Article in Polish] by Krysiak R¹, Kedzia A, Okopień B.(PubMed)
(7) The clinical evaluation of hirsutism by Somani N¹, Harrison S, Bergfeld WF.(PubMed)
(8) Polycystic ovary syndrome and insulin: our understanding in the past, present and future by Mayer SB¹, Evans WS, Nestler JE.(PubMed)
(9) Association of mean platelet volume with androgens and insulin resistance in nonobese patients with polycystic ovary syndrome by Dogan BA¹, Arduc A², Tuna MM¹, Karakılıc E¹, Dagdelen I¹, Tutuncu Y¹, Berker D¹, Guler S¹.(PubMed)
(10) Approach to the patient: contraception in women with polycystic ovary syndrome by Yildiz BO¹.(PubMed)
(11) Polycystic ovarian syndrome (PCOS): a significant contributor to the overall burden of type 2 diabetes in women by Talbott EO¹, Zborowski JV, Rager JR, Kip KE, Xu X, Orchard TJ.(PubMed)
(12) Prevalence of vitamin D deficiency in Slovak women with polycystic ovary syndrome and its relation to metabolic and reproductive abnormalities by Figurová J¹, Dravecká I, Javorský M, Petríková J, Lazúrová I.(PubMed)
(13) Role of Insulin Sensitizers on Cardiovascular Risk Factors in Polycystic Ovarian Syndrome: A Meta-Analysis by Thethi TK¹, Katalenich B², Nagireddy P³, Chabbra P⁴, Kuhadiya N⁵, Fonseca V¹.(PubMed)
(14) Acne in hirsute women by Lumezi BG¹, Pupovci HL¹, Berisha VL¹, Goçi AU², Gerqari A³.(PubMed)
(15) Obesity and polycystic ovary syndrome by Naderpoor N¹, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(PubMed)
(16) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H¹, Deeks A, Moran L.(PubMed)
(17) Metabolic Evidence of Diminished Lipid Oxidation in Women With Polycystic Ovary Syndrome. by Whigham LD¹, Butz DE², Dashti H³, Tonelli M³, Johnson LK¹, Cook ME², Porter WP⁴, Eghbalnia HR⁵, Markley JL⁶, Lindheim SR⁷, Schoeller DA⁸, Abbott DH⁹, Assadi-Porter FM¹⁰.(PubMed)
(18) Risk of endometrial, ovarian and breast cancer in women with polycystic ovary syndrome: a systematic review and meta-analysis by Barry JA¹, Azizia MM¹, Hardiman PJ².(PubMed)
(19) Risk of cancer among women with polycystic ovary syndrome: a Danish cohort study by Gottschau M¹, Kjaer SK², Jensen A¹, Munk C¹, Mellemkjaer L³.(PubMed)
(20) Polycystic ovary syndrome: metabolic consequences and long-term management by Carmina E¹.(PubMed)
(21) Arterial stiffness is increased in asymptomatic nondiabetic postmenopausal women with a polycystic ovary syndrome phenotype by Armeni E¹, Stamatelopoulos K, Rizos D, Georgiopoulos G, Kazani M, Kazani A, Kolyviras A, Stellos K, Panoulis K, Alexandrou A, Creatsa M, Papamichael C, Lambrinoudaki I.(PubMed)
(733) [Treatment of PCOS without IVF: weight loss, insulin-sensitizing agents].[Article in French] by Pugeat M¹.(PubMed)
(734) A 12-week treatment with the long-acting glucagon-like peptide 1 receptor agonist liraglutide leads to significant weight loss in a subset of obese women with newly diagnosed polycystic ovary syndrome by Jensterle M¹, Kravos NA¹, Pfeifer M¹, Kocjan T¹, Janez A¹.(PubMed)
(735) Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome by Esmaeilzadeh S, Andarieh MG¹, Ghadimi R, Delavar MA.(PubMed)
(736) Obesity and polycystic ovary syndrome by Naderpoor N¹, Shorakae S, Joham A, Boyle J, De Courten B, Teede HJ.(737)
(737) Polycystic ovary syndrome: a complex condition with psychological, reproductive and metabolic manifestations that impacts on health across the lifespan by Teede H¹, Deeks A, Moran L.(PubMed)
(738) A retrospective study of the pregnancy, delivery and neonatal outcome in overweight versus normal weight women with polycystic ovary syndrome by De Frène V¹, Vansteelandt S², T'Sjoen G³, Gerris J⁴, Somers S⁴, Vercruysse L⁴, De Sutter P⁴.(PubMed)
(739)  Carbohydrate(CDC)
(740) Effect of simple and complex carbohydrates on plasma non-esterified fatty acids, plasma-sugar, and plasma-insulin during oral carbohydrate tolerance tests by Swan DC, Davidson P, Albrink MJ.(PubMed)
(741) Carbohydrates and health: Not that simple...or that complex. Taking control of your blood sugar and insulin levels may pay off for your heart and overall health by [No authors listed](PubMed)
(742) Protein–DNA interaction(Wikepedia)
(743) Protein in your pregnancy diet(Babycenter)
(744) Energy and protein intake in pregnancy by Kramer MS¹, Kakuma R.(PubMed)

(745) Decreased lipases and fatty acid and glycerol transporter could explain reduced fat in diabetic morbidly obese by Ferrer R¹, Pardina E, Rossell J, Baena-Fustegueras JA, Lecube A, Balibrea JM, Caubet E, González O, Vilallonga R, Fort JM, Peinado-Onsurbe J.(PubMed)
(746) Fat(Wikipedia)
(747) All fats are not bad: a smart lesson to be learned by Ablin RJ, Jiang WG.(PubMed)
(748) Bad fats, good fats: new insights into diet and health.[No authors listed](PubMed)
(749)  Dietary fats in your pregnancy diet(BabyCenter)
(750) Potatoes, glycemic index, and weight loss in free-living individuals: practical implications by Randolph JM¹, Edirisinghe I, Masoni AM, Kappagoda T, Burton-Freeman B.(PubMed)
(751) No difference in body weight decrease between a low-glycemic-index and a high-glycemic-index diet but reduced LDL cholesterol after 10-wk ad libitum intake of the low-glycemic-index diet by Sloth B¹, Krog-Mikkelsen I, Flint A, Tetens I, Björck I, Vinoy S, Elmståhl H, Astrup A, Lang V, Raben A.(PubMed)