Catnip is also known as catswort, or catmint, a plant of Nepeta, belonging to the family of Lamiaceae, native to Europe and Asia. It has been use in herbal medicine as insect repellant and to treat digestive disorders, children restlessness and nervousness, fevers, cold and flu, skin irritations stimulate sweating, promote menstruation, etc..
Ingredients
Beside the major constituent of terpenoid
nepetalactone, the herb also contains α-Pinene, β-Pinene,
Cyclohexen-1-yl-methyl ketone, Triplal, Thymol, Nepetalactone,
Nepetalactone, etc.
Herbal catnip may be used as anti inflammatory agonist in treating
chronic related inflammation disease. 4aα,7α,7aβ-nepetalactone and
1,8-cineole, a chemical compound from catnip, found in the main
concentrated components of NP essential oil, showed to
alleviate symptoms of both the acute and chronic forms of nociception,
through its anti inflammatory effect in does
depending manner, ibn rat study(1). In support of the above, the Tarbiat
Modares University study showed that Nepeta crispa essential oil enhances anti-inflammatory effects in the formalin-induced paw inflammation model and significantly reduced the paw oedema in all applied doses(2).
The coincidence of the proven inflammatory
effect with insistence of herbalist may be due to its inhibition
of calcineurin; an important regulator of T-cell mediated inflammation
that has received little attention in ethnopharmacological research,
Dr. Prescott TA and the research team at the Royal Botanic Gardens
suggested(3).
Side effects1. Overdose of Catnip may cause central nervous system depression.
2.
Long-term exposure induced tolerance to stereotypic behavior,
catalepsy and sleeping time, and increased the susceptibility to
seizures.
3. Catnip may interacts with other medication if used on a daily basis
4. Etc.
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References
(1) Evaluation of the antinociceptive and anti-inflammatory effects of essential oil of Nepeta pogonosperma Jamzad et Assadi in rats by Ali T, Javan M, Sonboli A, Semnanian S.(PubMed)
(2) Antinociceptive and anti-inflammatory activities of the essential oil of Nepeta crispa Willd. in experimental rat models by Ali T, Javan M, Sonboli A, Semnanian S.(PubMed)
(3) Direct inhibition of calcineurin by caffeoyl phenylethanoid glycosides from Teucrium chamaedrys and Nepeta cataria by Prescott TA, Veitch NC, Simmonds MS.(PubMed)
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