Healthy Weight loss is defined as a reduction of
the total body mass for the purpose in improving heath due to related
illness, including heart diseases, stroke, over expression of
cholesterol, fatty liver, etc.
Non-alcoholic Fatty Liver Disease
is defined as a condition of the fatty liver diseases as a result of
accumulated of fat in the liver, not caused by abusive alcohol
consumption.
Non alcoholic fatty liver diseases is widespread in
Western world with no affirmative treatment. Most physicians suggested
healthy diet with less in saturated and trans fat and reduction of
patients' weight would be beneficial in management of the disease. As n-3
polyunsaturated fatty acids (PUFA)has been found to be effective in
treating patients with nonalcoholic fatty liver disease (NAFLD) associated with hyperlipidemia with no adverse effects. In the study of the effect of weight reduction diet as an exclusive treatment for NAFLD, in 44 patients with NAFLD
whom received a diet including a 500 to 1000 kcal per day intake
reduction
as30% fat, 15% protein, and 55% carbohydrate for six months, reduction
of body weight, waist circumference and decrease diastolic blood
pressure are significant. Total cholesterol, LDL, triglyceride, ALT,
AST, GGT and CK18-M30 levels were significantly decreased as well. Of
these result, weight reduction diet should be considered as a therapy in
managing non alcoholic liver disease.
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References
(1) How Much Weight Loss is Effective on Nonalcoholic Fatty Liver
Disease? by Ghaemi A, Taleban FA, Hekmatdoost A, Rafiei A, Hosseini V,
Amiri Z, Homayounfar R, Fakheri H.(PubMed)
(2) Effects of n-3 polyunsaturated fatty acids from seal oils on
nonalcoholic fatty liver disease associated with hyperlipidemia by Zhu
FS, Liu S, Chen XM, Huang ZG, Zhang DW.(PubMed)
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