Phytochemicals, the natural chemical
constituent, protect the plants against diseases and form their
outer's color. Phytochemicals may be next potential sources of new
medicine for treatment of
diseases with little or no side effects.
Piperine is a phytochemical alkaloid in the class of organosulfur compound, found abundantly in white and black pepper, long pepper, etc.
The immune system is the
set of cells and their activity against antigens or infectious agents
that comprises of the body's defense system against diseases. The
immune system does a great job of keeping people healthy and preventing
infections. Beside foods and nutritional supplements, herbs also play a
important role in helping the immune system defend against viruses and
bacteria attacks.
The health benefits
In the study of piperine combination with
mupirocin for antimicrobial activity against Staphylococcus aureus
strains including meticillin-resistant S. aureus, the combination
showed more effective against the tested subject when compared with the
commercially available formulation of 2 % mupirocin alone. Other in the
study of the same subject showed the enhanced accumulation and decreased
efflux of ethidium bromide in the wild-type and mutant (CIPr-1) strains
in the presence of piperine.
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References
(1) Piperine as an inhibitor of the MdeA efflux pump of Staphylococcus aureus by Mirza ZM, Kumar A, Kalia NP, Zargar A, Khan IA.(PubMed)
(2) Piperine, a phytochemical potentiator of ciprofloxacin against Staphylococcus aureus by Khan IA, Mirza ZM, Kumar A, Verma V, Qazi GN.(PubMed)
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