Polycystic Ovarian Syndrome is defined as
endocrinologic diseases caused by undeveloped follicles clumping on the
ovaries that interferes with the function of the normal ovaries as
resulting of enlarged ovaries, leading to hormone imbalance( excessive
androgen), resulting in male pattern
hair development, acne,irregular period or absence of period, weight
gain and effecting fertility. It effects over 5% of women population or 1
in 20 women.
Aloe Vera is species of succulent plant in the genus
Aloe, belonging to the Family Xanthorrhoeaceae, native to Sudan. It has
become very popular for commercial cultivation due to its health
benefits. Aloe vera has been used in herbal medicine in treating many
kinds of disease, including wound, burn healing, minor skin infections,
sebaceous cysts, diabetes, and elevated of cholesterol, etc. It is
also one of many popular herb studied in scientific ways with some
conflicted results.
The effects
In the view if certain side effects of several classes of
pharmacological agents have been used to manage dyslipidemia in women
with Polycystic Ovarian Syndrome (PCOs), some researchers have been
studied through the altyernative nmedicine with an aim to find a better
treatment with less or no side effects. Aloe vera gel (AVG), has found
to be effective in reduction in plasma triglyceride and LDL cholesterol
levels, with an increase in HDL cholesterol, reversion of abnormal
estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme
activities. Others in the study of the same but in comparison with
Letrozole, showed Aloe vera restored the estrus cyclicity, glucose
sensitivity, and steroidogenic activity. Treatment combined with
Letrozole prevented the development of the PCO phenotype. These results
showed a positive anti-hyperlipidemic effects and may be used in
managing PCOS associated metabolic complication and restoring the ovarian steroid status.
The Side effects 1. High amount of vitamin K may reduce the effectiveness of anticogulation medicine
2. Causing additive effects for women who are under estrogen replacement therapy or taking the oral contraceptive pill.
3. It may cause stomach upset and diarrhea
4. The herb may induce lupus erythematosu due to its chemical constituent L-canavanine.
Ovarian Cysts And PCOS Elimination
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal
in a letrozole-induced polycystic ovarian syndrome rat model by Desai
BN, Maharjan RH, Nampoothiri LP.(PubMed)
(2) Effect of Aloe barbadensis Mill. formulation on Letrozole induced
polycystic ovarian syndrome rat model by Maharjan R, Nagar PS,
Nampoothiri L.(PubMed)
(3) Drug-induced lupus: an update by Vasoo S.(PubMed)
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