Selective serotonin re-uptake inhibitors or serotonin-specific reuptake inhibitor (SSRIs)
are a types of antidepressant medications to treat depression and
certain neurological disorders, including obsessive-compulsive
disorder, panic disorder (PD), generalized anxiety
disorder, post traumatic stress disorder (PTSD), and social anxiety
disorder (SAD), etc..
SSRI discontinuation syndrome is defined as a condition of a
syndrome as a result of interruption, reduced doses or discontinuation
of any anti depressant medication, including SSRI (selective serotonin
re-uptake inhibitor) and serotonin–norepinephrine reuptake inhibitor
(SNRI), researchers showed that The SSRI discontinuation syndrome is a characteristic selective serotonin reuptake inhibitor (SSRI) discontinuation syndrome
appears to exist. It is usually mild, commences within 1 week of
stopping treatment, resolves spontaneously within 3 weeks, and consists
of diverse physical and psychological symptoms, the commonest being
dizziness, nausea, lethargy and headache. SSRI reinstatement leads to resolution within 48 h(1).
Treatments
C. In traditional Chinese medicine perspective
According to APPENDIX 1: Guipi Tang and SSRI Withdrawal Syndrome,
Western interpretation of the symptoms as relative deficiency in
serotonin availability or
an imbalance of neurotransmitters after the drugs are
removed. In TCM the withdrawal syndrome may be caused qi and
blood deficiency, as a result of the
spleen (for qi) and liver (for blood). Treatment of SSRI withdrawal
syndrome is depending to the differentiation of the symptom(29). Herbs used
include
Atractylodes (white atractylodes): tonifies qi, resolves damp
Peony (white peony): nourishes blood, vitalizes blood circulation
Tang-kuei: nourishes blood, vitalizes blood circulation
Zizyphus: nourishes liver and heart blood and clams shen
Saussurea: circulates qi, calms shen
Ginseng: tonifies qi, calms shen
Astragalus: tonifies qi, raises yang qi
Polygala: resolves phlegm, calms shen
Fu-shen or Hoelen: resolves damp, calms shen
Pinellia: resolves damp, lowers stomach qi
Citrus: resolves damp, circulates qi
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Sources
(1) http://www.ncbi.nlm.nih.gov/pubmed/10958258
(29) http://www.dr-bob.org/babble/alter/20100516/msgs/947782.html
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