Risk-benefit analysis of a hCG-500 kcal reducing diet

Human chorionic gonadotropin or human chorionic gonadotrophin (hCG) is a hormone produced during pregnancy, made by the developing embryo after conception.
In the review of the British physician A.T.W. Simeons' combined a reduction diet (500 kcal per day) with daily injections of the pregnancy hormone human chorionic gonadotropin (hCG) (125 IU i.m.), showed that showed a significant weight reduction during dieting, but no differences between treatment groups in respect of body weight, body proportions and feeling of hunger. One of them is the only German study conducted by Rabe et al. in 1981 in which 82 randomised premenopausal volunteers had been dieting either with hCG or without hCG injections. In recent publications describing mostly well-documented double-blind studies authors largely reject hCG administration in dieting. Supporters of the hCG diet must prove the efficacy of this method in controlled studies according to the German Drug Law. Until then the opinion of the German steroid toxicology panel is still valid, that hCG is ineffective in dieting and should not be used (Bolt 1982 a, 1982 b)(1)


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(1) "[Risk-benefit analysis of a hCG-500 kcal reducing diet (cura romana) in females].
[Article in German]" byRabe T, Richter S, Kiesel L, Runnebaum B.