Human chorionic gonadotropin or human chorionic gonadotrophin (hCG) is a
hormone produced during pregnancy, made by the developing embryo after
conception.
In the evaluation of a 24-year-old woman with weight
loss-related amenorrhea underwent ovulation induction and
intracytoplasmic sperm injection (ICSI). Administration of exogenous
gonadotropins was ineffective in ovulation induction. Supplementation
with low-dose hCG in order to increase luteinizing hormone (LH) activity
in the late follicular phase produced late folliculogenesis and
steroidogenesis, and ovulation was then successfully induced(1)
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(1)
"Successful pregnancy following low-dose hCG administration in addition
to hMG in a patient with hypothalamic amenorrhea due to weight loss" by Tsutsumi R, Fujimoto A, Osuga Y, Harada M, Takemura Y, Koizumi M, Yano T, Taketani Y.
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