Cerebritis is defined as an inflammation of the cerebrum, a structure associated with memory, speech, etc., as a result of the formation of an abscess within the brain itself, found commonly in patients with lupus.
Systemic lupus
erythematosus (SLE) or Lupus is a chronic, autoimmune
disease as as a result of the development of
autoantibodies that attack the systems and organs in the
body.researchers at the indicated that saturated fatty acid palmitate,
but not unsaturated oleate, induces the
activation of the NLRP3-ASC inflammasome, causing caspase-1, IL-1β and
IL-18 production.
Lupus
cerebritis is a disorder of nervous system problems (an autoimmune
inflammatory disorder) caused
by lupus as as a result of the development of
autoantibodies that attack the systems and organs in the body. It causes
migraine headache, if the duration of the
central nervous system involvement last for a few minutes, or causes
dementia that can lead to neurological deficits as a transient attacks
or permanently.
Prevention
A. What to avoid
Any thing which cause inflammation must be avoid. thyere is a report found that SLE patients and lupus-prone mice induces skin inflammation following intradermal injection into normal mice. Lupus serum depleted of IgG failed to cause skin inflammation(36). including
1. Sugar
Refined sugar with high glycemic values cause fluctuation of insulin
levels and
put the immune system on high alert. In the
evaluation of one hundred and eleven serum samples were assayed from
patients with
Graves' disease, primary hypothyroidism, chronic autoimmune thyroiditis,
Addison's disease, chronic autoimmune hepatitis, pernicious anemia, lupus
erythematosus, and rheumatoid arthritis, together with 45 serum samples
from normal subjects, conducted by Clinic of Endocrinology, University
La Sapienza, showed that contrary to expectation anti-immunoglobulin
antibodies are not
associated with non-diabetes-related autoimmune diseases, increased
humoral immunoresponsiveness to endogenous insulin appears to be related to autoimmunity in general rather than restricted to Type I diabetes.(33)
2. Saturated and trans fat
Saturated fat and trans fat trigger and stimulate the immune system's
inflammatory response. In the study of Fatty acid–induced NLRP3-ASC
inflammasome activation interferes with insulin signaling, Dr. Haitao
Wen, and the team indicated that High-fat diet (HFD) and inflammation
are key contributors to insulin
resistance and type 2 diabetes (T2D). Interleukin (IL)-1β plays a role
in insulin resistance, yet how IL-1β is induced by the fatty acids in an
HFD, and how this alters insulin signaling, is unclear. We show that
the saturated fatty acid palmitate, but not unsaturated oleate, induces
the activation of the NLRP3-ASC inflammasome(34)
3. Diary products
Diary products can cause allerdic effect that lead to the production
immunoglobulin E antibodies, histamine, etc., causing immune system
malfunction.
4. Process foods
In an article of Inflammatory Foods, Consider avoiding to achieve
Natural remission in RA, the author wrote "often times people reduce the
intake of inflammatory foods but fail to
recognize all the hidden places, generally in processed foods, that
these foods are being consumed.
Many arthritic symptoms are triggered by allergies" (35) that can lead
to inflammation.
5. Smoking and alcohol
In the assessment of whether smoking or alcohol consumption is associated with lupus
erythematosus (LE), conducted by Place de l'hôpital, Dr. Boeckler P and
the team showed that cigarette smoking is associated with LE, but alcohol
consumption is not. The risk conferred by cigarette smoking seems
highest in patients who meet fewer than 4 ACR criteria and/or who do not
have antinuclear DNA antibodies(37)
6. Refined products
Refined grains pattern was positively related to sICAM-1 (P for trend = 0.007)(38)
7. Artificial ingredients
There is a report that scientists disagree about the relationships between sweeteners and
lymphomas, leukemias, cancers of the bladder and brain, chronic fatigue
syndrome, Parkinson's disease, Alzheimer's disease, multiple sclerosis,
autism, and systemic lupus.(39)
8. Allergic effects
Allergic effect can increase the risk of the development of lupus as a
result of inflammation caused by immune system malfunction.
9. Etc.
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Sources
(33) http://www.ncbi.nlm.nih.gov/pubmed/2183533
(34) http://www.nature.com/ni/journal/v12/n5/full/ni.2022.html
(35) http://www.livingwithrheumatoidarthritis.com/Inflammatory-foods.html
(36) http://www.ncbi.nlm.nih.gov/pubmed/20483718
(37) http://www.ncbi.nlm.nih.gov/pubmed/19770440
(38) http://www.ncbi.nlm.nih.gov/pubmed/15447916
(39) http://www.ncbi.nlm.nih.gov/pubmed/18604921
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