Antioxidant Moronic Acid, a Natural and Potential Anti-HIV Agents

By Kyle J. Norton

Human immunodeficiency virus -1 (HIV-1) is one of 2 types of HIV precipitated of acquired immunodeficiency syndrome (AIDS), transmitted through direct contact with HIV-infected body fluids, including blood, semen, and genital secretions,...

Acquired immunodeficiency syndrome (AIDS) is a chronic condition caused by the infection of the human immunodeficiency virus (HIV).

According to epidemiological studies, people who serval sexual partners are the most at risk of HIV infection.

However, the virus can also transmit through infected blood transfusion, infected mother to children.

Most people infected by the HIV virus may experience symptoms of fever, muscle aches and joint pain similar to those of influenza in the early stage of the viral attacks.

People in the early stage infected by the virus may experience some acute symptoms caused by the immune response, including fever sore throat, rash, muscle and joint aches and pains, headache,...

If untreated, the virus will slowly multiply and destroy the cells of the immune system, leading to chronic signs and symptoms of fever, fatigue, swollen lymph nodes,...

In the late stage, HIV-1 may severely damage the immune system, making the infected host vulnerable to a variety of life-threatening diseases and cancers. If an infected individual has the numbers of T-cell count below 200, the person is considered to have AIDs.

According to the statistic, AIDS is the fifth leading cause of death in the US.

People between ages 25 and 44 in the United States are at substantially higher risk compared to other age groups.

According to statistics, approximately 36.7 million people worldwide living with HIV/AIDS in 2016, including, 2.1 million children less than 15 years of age.

Moronic acid is a phytochemical in the subclass of Triterpenoid, belonging to the group of Terpenes found in extracted from Rhus javanica, Mistletoe, etc.

On finding a potential phytochemical for the prevention of viral infection, researchers compared the anti-HIV activity of seven new triterpene derivatives.

According to the results of differentiation,

* Moronic acid derivatives 19, 20, and 21 showed significant activity in HIV-1 infected H9 lymphocytes.

* Furthermore, in the MT-4 cell line, compounds 19 and 20 showed strong effects against HIV-1 NL4-3 and drug-resistant strains in the MT-4 cell line compared to the betulinic acid analog 8 (PA-457), which has successfully completed a Phase IIa clinical trial.

* Moreover, the compound 20 showed potent anti-HIV activity with EC50 values of 0.0085 microM against NL4-3, 0.021 microM against PI-R (a multiple protease inhibitor resistant strain), and 0.13 microM against FHR-2 (an HIV strain resistant to 8).

Based on the findings, researchers said, "Promising compound 20 has become a new lead for modification, and further development of 20-related compounds as clinical trial candidates is warranted".

Taken altogether, moronic acid may be considered a promising anti-HIV agent,  pending to the confirmation of the larger sample size and multicenter human study.

Intake of moronic acid in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

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Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Anti-AIDS agents 69. Moronic acid and other triterpene derivatives as novel potent anti-HIV agents by Yu D1, Sakurai Y, Chen CH, Chang FR, Huang L, Kashiwada Y, Lee KH. (PubMed)

Herbal Ashwagandha Protects the Heart Against Damage in Post Myocardial Injury

By Kyle J. Norton

The circulatory system consists of the heart, blood vessels, and blood with the function to transport of nutrients, oxygen, and hormones to cells throughout the body and removal of metabolic wastes (carbon dioxide, nitrogenous wastes).

Cardiovascular disease is a class of chronic conditions associated with the heart and blood vessels.

According to the statistic cardiovascular disease is the leading cause of death in women in the US with 90% of women having one risk factor.

Believe it or not, women are 4 times more likely to die from heart disease than breast cancer and 2/3 of women are not aware of heart disease risk for them, according to the Jean Hailes for Women Health in the article cardiovascular health.

Heart disease is a class of diseases associated with interruption of blood flow in the blood vessel or damage of the heart tissue, including coronary artery diseases (CAD) such as angina and myocardial infarction.

According to the statistics, heart disease is a leading cause of death in the US. Approximately 2000 people in the general population die of heart disease every day.

Coronary heart disease (CHD) is the most common type of heart disease, that kills over 370,000 people annually.

The causes of cardiovascular diseases are associated with the accumulation of plaques in the arteries, impeding the blood flow which carries the nutrients and oxygen to the heart, causing damage to the heart tissue and reduced function of the arteries.

In other words, high blood pressure, high blood cholesterol, smoking, diabetes, weight, depression and family history associated with the early onset of plaques accumulated and impeding function of the arteries are the prevalent risk factors of cardiovascular diseases.

The World Heart Foundation, in the investigation of CVD, suggested that CVD risk factors can be classified by
* Non-Modified risk factors such as age, ethnic background,....... and family history. The risk that can not be controlled

* Modified risk factors such as smoking, high blood cholesterol, and pressure, diabetes physical inactivity,.... and overweight. These types of risks can be controlled through a change in lifestyle and diet.

Ashwagandha also is known as Withania somnifera is a nightshade plant in the genus of Withania, belonging to the family Solanaceae, native to the dry parts of India, North Africa, Middle East, and the Mediterranean.

The herbal medicine has been considered as Indian ginseng and used in Ayurvedic medicine over 3000 years to treat tumors and tubercular glands, carbuncles, memory loss, and ulcers and considered as anti-stress, cognition-facilitating, anti-inflammatory, and anti-aging herbal medicine.


In the urgency to discover a natural ingredient for the promotion of cardio-functioning, researchers examined the efficacy of Withania somnifera (Ws) to limit myocardial injury after ischemia and reperfusion compared to that of Vit E,

The study included Wistar rats (150-200 g) that were divided into six groups and received orally saline (sham, control group), Ws-50/kg (Ws control and treated group) and Vit E-100 mg/kg (Vit E control and treated group) respectively for 1 month.

According to the results of the experiment of Vit E and Ws treated groups that were anesthetized subjected to 45 min occlusion of the LAD coronary artery followed by 60 min reperfusion on the 31st day,

* Postischemic reperfusion rats showed significant cardiac necrosis, depression of left ventricular functions (MAP, LVEDP, (+) and (-)LVdP/dt) and a significant fall in GSH (p < 0.01), SOD, CAT (p < 0.05).

* Postischemic reperfusion rats also demonstrated a fail in LDH and increased cardio stress markers and levels of  MDA, compared to the sham group. 

* In comparison tested, Ws and Vit E favorably modulated most of the hemodynamic, biochemical and histopathological parameters though no significant restoration in GSH, mean arterial pressure VAP.

* More importantly, chronic administration of Ws on markedly augmented antioxidants (GSH, GSHPx, SOD, CAT) compared to Vit E that does not stimulate the synthesis of endogenous antioxidants compared to sham.

Based on the evidence, researchers said, "Ws significantly reduced myocardial injury and emphasize the beneficial action of Ws as a cardioprotective agent".

Taken altogether, Ashwagandha may be considered supplements for the treatment of myocardial injury, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Cardioprotection from ischemia and reperfusion injury by Withania somnifera: a hemodynamic, biochemical and histopathological assessment by Gupta SK1, Mohanty I, Talwar KK, Dinda A, Joshi S, Bansal P, Saxena A, Arya DS. (PubMed)

Broccoli Modulates the Immune Response

By Kyle J. Norton

Immunomodulators are agents that modify the immune response or the functioning of the immune system such as the stimulation of antibody formation or the inhibition of abnormal white blood cell activity.

In other words, immunomodulation processed immunotherapy, in which immune responses are induced depending on the body's needs.

The immune system is the set of cells and their activity against antigens or infectious agents that comprises the body's defense system against diseases.

The immune system does a great job of keeping people healthy and preventing infections.

Besides foods and nutritional supplements, herbs also play important roles in helping the immune system to defend against viruses and bacteria attacks.

The immune response is a natural reaction of the immune system to protect our body against the invasion of foreign substances.

Inflammation is a natural response of the immune system which protects the body against the invasion of pathogens.

In the acute phase of infection, the immune system initiated the production of proinflammatory Th1 cytokines in activated interleukin-12 (IL-12) and gamma interferon (IFN-γ) and other pro-inflammatory factors such as TNF beta in response to detect, engulf and destroy pathogens and apoptotic cells through macrophages.

These activities played an important in inducing apoptosis and reducing the proliferation of bacteria or viruses by attaching to the surface of the injured cells to initiation of an alternation. however, overproduction of pro-inflammatory expression may indeed cause substantial adverse effects in tissue destruction, and, in some cases, shock and death.

Type 1 T helper (Th1) in response to tissue damage and injure also activated macrophages that are responsible for cell-mediated immunity and phagocyte-dependent protective activity.


Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae. The veggie has large flower heads, usually green in color with a mass of flower heads surrounded by leaves and evolved from a wild cabbage plant from the continent of Europe.

On findings a natural wholefood for the prevention of infectious disease, researchers examined the effects of Quercetin, a great representative of polyphenols, flavonoids subgroup, flavonols found in broccoli on the immune response.

Quercetin exhibited antioxidant activity in radical scavenging and anti-allergic properties by stimulation of the immune system against the antiviral activity, histamine release,

Furthermore, quercetin also modulated the immune response by decreasing the pro-inflammatory cytokines, leukotrienes creation, and suppressing interleukin IL-4 production.

The antioxidant improved the Th1/Th2 balance, and restrain antigen-specific IgE antibody formation.

Moreover, quercetin was also effective in the inhibition of enzymes such as lipoxygenase, eosinophil, and peroxidase by suppressing inflammatory mediators.

Based on the results, researchers wrote, " All mentioned mechanisms of action contribute to the anti-inflammatory and immunomodulating properties of quercetin that can be effectively utilized in the treatment of late-phase, and late-late-phase bronchial asthma responses, allergic rhinitis, and restricted peanut-induced anaphylactic reactions".

And "Plant extract of quercetin is the main ingredient of many potential anti-allergic drugs, supplements and enriched products".

Taken altogether, broccoli containing high amounts of quercetin may be considered a functional food for the improvement of the immune response,  pending to the confirmation of the larger sample size and multicenter human study.




Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Quercetin and Its Anti-Allergic Immune Response by Mlcek J1, Jurikova T2, Skrovankova S3, Sochor J. (PubMed)

Omega-3 Fatty Acids Inhibit the Chain Reaction of Reactive Oxygen Species (ROS)

By Kyle J. Norton


Reactive oxygen species (ROS) or free radicals are highly reactive chemical species containing oxygen molecules. In other words, free radicals are unstable atoms with an unpaired electron in the outer ring.

Therefore, in order to become stable, free radicals must either donate or steal an electron from other atoms, leading to a chain reaction that can not be stopped until all electrons are paired or inhibited by antioxidants.

Believe it or not, free radicals in moderate amounts are needed for our body for cell signaling and activation of several transcriptional factors, apoptosis, immunity, and differentiation. However, overexpression of free radicles can cause damage to protein, lipid, and cell alternation, leading a number of chronic illnesses, including cancer.

Free radicals are generated as metabolic by-products by biological systems. Environmental stressors (i.e., the air we breathe, UV, ionizing radiations, pollutants, and heavy metals) and xenochemicals are also found to contribute to the great increase of ROS production.

In a healthy individual, the production of free radicals is balanced by the antioxidant enzymes produced by the body.

Antioxidants are stable atom that plays a critical role in protecting the body against the attack of free radicals.

In other words, antioxidants inhibited the onset of free radical before they can cause a chain reaction in facilitating the protein, lipid, and cell damage.

Antioxidants can either produced by the liver or intake from dietary sources. Under normal conditions, antioxidant enzymes produced by the body in a healthy individual are good enough to counter the bombardment of free radical attacks.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the treatment of diseases associated with oxidative stress, researchers examined the intake of EPA:DHA 6:1 (500 mg/kg/day) for 2 weeks on endothelial dysfunction in old rats (20 months old).

According to the results of the analysis,

Before application with DHA

* Endothelial dysfunction characterized by a blunted NO component, an abolished endothelium-dependent hyperpolarization component, and increased endothelium-dependent contractile responses (EDCFs) are observed in old rats compared to young rats.

* Furthermore, age-related endothelial dysfunction was found to increase the vascular formation of reactive oxygen species (ROS) and expression of eNOS.

After treatment with DHA

* The EPA:DHA 6:1 treatment improved the NO-mediated relaxation, reduced the EDCF-dependent contractile response and the vascular formation of ROS, and normalized the expression level of all target proteins in the old arterial wall.

Collectively, researchers said, "a 2-week intake of EPA:DHA 6:1 by old rats restored endothelium-dependent NO-mediated relaxations, most likely, by preventing the upregulation of the local angiotensin system and the subsequent formation of ROS".

Taken altogether, Omega-3 fatty acids found abundantly in fish oil and plant oil may be considered a functional food for the prevention of diseases associated with ROS, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Intake of omega-3 formulation EPA:DHA 6:1 by old rats for 2 weeks improved endothelium-dependent relaxations and normalized the expression level of ACE/AT1R/NADPH oxidase and the formation of ROS in the mesenteric artery by Farooq MA1, Gaertner S2, Amoura L1, Niazi ZR1, Park SH1, Qureshi AW1, Oak MH1, Toti F1, Schini-Kerth VB3, Auger C. (PubMed)

Herbal Angelica Promotes the Healing of Gastric Ulcer in Vivo

By Kyle J. Norton

Gastric ulcer is the medical condition characterized by the open sores that develop on the inside lining of the stomach. If the open sores are developed in the upper part of the small intestine, it is a duodenal ulcer.

The most common cause of the gastric ulcer, represented over 30% of all cases is associated with the infection of H. pylori.

Certain medical conditions such as Zollinger-Ellison syndrome and long-term use of some medication such as alendronate (Fosamax) and risedronate (Actonel) are also prevalent factors that elevate the disease onset.

The imbalance between stomach acid and upper GI tract mucosa is the main cause of the condition onset associated with the use of certain medication, including aspirin, and non-steroidal anti-inflammatory drugs, Helicobacter pylori infection and chronic gastritis.

Most common symptoms of a gastric ulcer are gastrointestinal discomforts, blood in your stool, difficulty breathing, shortness of breath with physical activity, and persistent fatigue.

Some patients with severe gastric ulcers may also experience symptoms of vomiting blood, feeling faint or losing consciousness. However, 75% of patients with gastric ulcers do not feel any symptoms.

Long-term untreated gastric ulcer can result in gastric adenocarcinoma development.

Although there are some disagreements that a poor diet can cause gastric ulcers, some researchers suggested that a diet rich, fatty or spicy foods such as the Western diet and unhealthy lifestyle such as high caffeine. and excessive alcohol consumption also elevates the onset of the disease.

Therefore by following a healthy diet with more fruits and vegetables, whole grain and less red meat and processed foods accompanied by a healthy choice of lifestyle and moderate exercise, one can lower the risk gastric ulcer substantially.

On finding a natural ingredient for the prevention and treatment of digestive diseases, scientists examined the crude extract from Angelica sinensis (ASCE) consisting of polysaccharides on normal gastric epithelial cells.

Angelica or Dang Qui is a herb of Genus Angelica from the family Apiaceae, indigenous to China.

The herb has been used as a Queen herb in traditional Chinese medicine antispasmodic and vasodilatory agent, and to balance the hormones in women for a normal menstrual cycle and menstruation and strengthen heart, spleen, kidneys, and liver for both men and women, etc. In other words, it is used to treat gynecological ailments, fatigue, mild anemia, and high blood pressure. It has analgesic, anti-inflammatory, etc.

According to the tested assays,

* ASCE showed a direct wound healing effect on gastric mucosa

* However, there is no report in which  ASCE exerted gastric ulcer healing in animal models.

* ASCE promoted ulcer healing by reducing the ulcer area, accompanied with a significant increase in mucus synthesis when compared with the control,

* Treatment of ASCE also inhibited angiogenesis, without affecting the cell proliferation associated with ODC and EGFR protein expression.

Based on the results, researchers suggest, "This fraction demonstrated insignificant antimicrobial activity and can be used in cosmetic and pharmaceutical industries".

Taken altogether, Dandelion may be considered an antioxidant remedy for speeding up gastric ulcer healing, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Effect of polysaccharides from Angelica sinensis on gastric ulcer healing by Ye YN1, So HL, Liu ES, Shin VY, Cho CH. (PubMed)

Broccoli, the Potential Anti-Prostate Cancer Healthy Food

By Kyle J. Norton

Prostate warped around the around a tube (the urethra) is a gland of the male reproductive system found in front of the rectum and just below the bladder and responsible for making some of the semen that carries sperm.

Prostate cancer is a condition in which the cells of the prostate have become cancerous, causing abnormal cell growth which spread to the distant parts of the body. Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during the Physical (rectum) exams.

Primary prostate cancer normally starts from the cell on the surface of the inner lining of the prostate tissue and gradually spreads to the deeper part of the prostate.

At the early stage, patients may not experience any symptoms, However, at the advanced stage, prostate cancer can induce symptoms of blood in the urine, frequent urination and urinary difficulty.

The cancer cells at this stage can also travel a distance away from the prostate to invade other healthy tissue and organ, leading secondary metastasis tumors.

According to the Canadian Cancer Society, in 2017, 21,300 men were diagnosed with prostate cancer, represented 21% of all new cancer cases and 4,100 men died from prostate cancer, and 10% of all cancer deaths.

The 5 years survival rate of localized prostate cancer is 100% and 98% of that of survivors are alive after 10 years compared to the advanced stage of only 31%.

More than 80% of prostate cancers are diagnosed in men who are 65 or older.

Therefore, men who are at higher risk of prostate cancer due to family history and increase in age and inherited gene changes should have their prostate gland checked annually.

Broccoli is a mustard/cabbage plant, belong to the family Brassicaceae. The veggie has large flower heads, usually green in color and the mass of flower heads surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.

On finding a potential plant that processes anticarcinogenic activity, researchers examined the effects of consuming broccoli soup on prostate tissue.

The study included 18 men scheduled for transperineal prostate biopsy recruited into a 4-week parallel single-blinded diet supplementation study (NCT02821728), with 9 men supplemented their diet with three 300 mL portions of a broccoli soup each week for four weeks prior to surgery.

According to the analyses of the prostate, biopsy tissues reveal no detectable levels of glucosinolates and derivatives on the baseline.

Where Glucosinolates (GLS) are secondary plant metabolites in cruciferous vegetables with a function to break-down products, prevention of cancer in animal and cell studies.

Injection of the supplementation of SMCSO demonstrated significantly higher levels of glucosinolates and derivatives in the tissue of men in the supplementation arm.

The urinary assay also suggested that SMCSO was found in blood and urine samples from a previous intervention study with the identical broccoli soup.

Based on the findings, researchers wrote, " The consequences of SMCSO accumulation in prostate tissues and its potential role in the prevention of prostate cancer...

In other words, the intake of SMCSO over a short period of time of 4 weeks reduces the risk of prostate cancer.

Taken altogether, the consequences of these results suggest that the broccoli process the potential anticarcinogenic activity by upregulating the gene associated with xenobiotic metabolism, pending to the confirmation of the larger sample size and multicenter human study.

Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Accumulation of Dietary S-Methyl Cysteine Sulfoxide in Human Prostate Tissue by Coode-Bate J1, Sivapalan T1, Melchini A1, Saha S1, Needs PW1, Dainty JR2, Maicha JB1, Beasy G1, Traka MH1, Mills RD3, Ball RY4, Mithen RF. (PubMed)

Antioxidants Omega -3 Fatty Acids in Reducing the Risk of Chronic Kidney Diseases in Females

By Kyle J. Norton

Kidneys are 2 bean-shaped organs found in the left and right side in the retroperitoneal space in the body.

The function of kidneys is to filter blood and control fluids. They are the second detoxed organs besides the liver and skin.

Due to millions of tiny filters called nephrons in each kidney, people may not experience any kidney dysfunction symptoms at an early stage.

Kidney diseases are a class of medical conditions associated with reduced function of the kidney, in cases, complete loss of kidney function such as kidney failure.

Believe it or not, in the US, the leading causes of kidney failure and the end stage of chronic kidney diseases are diabetes and high blood pressure.

Some researchers suggested that if the 2 causative conditions are under control, kidney failure and the end stage of chronic kidney diseases may be prevented or delayed.

Chronic Kidney disease is a condition associated with the progressive loss of kidney function over a period of many years. Stage of chronic kidney disease according to the National Kidney Foundation's Kidney Disease Outcomes Quality Initiative (KDOQ).

Stages and Description of Glomerular Filtration Rate  GFR (the number used to figure out a person's stage of kidney disease)
1. Signs of mild kidney disease but with normal or better GFR greater than 90%.
2. Mild kidney disease with reduced GFR 60-89%.
3. Moderate chronic renal insufficiency 30-59%.
4. Severe chronic renal insufficiency 15-29%.
5. End-stage renal failure of less than 15%.

According to the statistics, in the US, over 660,000 Americans have kidney failure, affecting 14% of the general population.

Omega-3 fatty acids are phytochemicals in the class of lipids, found abundantly in deepsea fisk, dark-green leafy vegetables, grains, legumes, nuts, etc.

The three main components of Omega-3 fatty acids are alpha-linolenic acid (ALA), eicosapentaenoic acid (EPA), and docosahexaenoic acid (DHA).

On finding a potential phytochemical for the protection of kidney activity researchers examined intakes of long-chain omega-3 polyunsaturated fatty acids (LCω3PUFA) and its food source-fish-on chronic kidney diseases (CKD) incidence.

A total of 4133 healthy individuals of black and white race aged 18-30 at baseline (1985-1986) from the Coronary Artery Risk Development in Young Adults study were enrolled and followed up over 25 years  

According to the results of the assessment of LCω3PUFA and fish intake by an interview-based dietary history questionnaire at baseline, year 7 (1992-1993) and 20 (2005-2006), 

* Four hundred and eighty-nine incident cases of CKD were identified.

* After adjustment for potential confounders, LCω3PUFA intake was inversely associated with CKD incidence.

* However, this inverse association was persisted among females [0.64 (95% CI 0.48, 0.84; P = 0.002], but not males.

* Non-fried fish consumption showed a marginally significant inverse association with CKD incidence.

Based on the findings, researchers said, "Dietary LCω3PUFA intake was inversely associated with the incidence of CKD among American young adults over 25 years of follow-up".

Taken altogether, Omega-3 fatty acids may be considered a functional food for the prevention and treatment of chronic kidney diseases,  particularly in females, pending to the confirmation of the larger sample size and multicenter human study.

Intake of Omega-3 fatty acids in the form of supplements should be taken with extreme care to prevent overdose acute liver toxicity.


Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight

How To Get Rid Of Eye Floaters 
Contrary To Professionals Prediction, Floaters Can Be Cured Naturally 

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You. How-To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca


Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bioscience, ISSN 0975-6299.

Sources
(1) Intakes of long-chain omega-3 polyunsaturated fatty acids and non-fried fish in relation to incidence of chronic kidney disease in young adults: a 25-year follow-up by Park I1,2, Xun P1, Tsinovoi CL1, Klemmer P3, Liu K4, He K. (PubMed)
(2) Omega-3 fatty acids for dialysis vascular access outcomes in patients with chronic kidney disease by Tam KW1, Wu MY, Siddiqui FJ, Chan ES, Zhu Y, Jafar TH. (PubMed)