Wednesday 13 December 2017

Food Therapy: Chick pea Pulses and Fibers in Reduced Risk of Metabolic Syndrome

Kyle J. Norton

Chickpea may have a profound effect in activated gut microbiota host energy homeostasis in modulated risk of metabolic syndrome, some studies suggested.

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to Middle East.

Metabolic syndrome is a set of conditions, including high blood pressure and blood sugar, excess body fat around the waist, and abnormal cholesterol or triglyceride levels which may contribute to the onset of cardiovascular disease and diabetes.

The effect of chickpea in reduced risk of metabolic syndrome has been investigated extensively through numbers of aspect and mechanism.

α-galactooligosaccharides (α-GOS) isolated from fermentable soluble fibers extracted of chickpea on high-fat-diet (HFD)-induced metabolic syndrome and gut bacterial dysbiosis in animal model, displayed a significant improvement of parameters which have a direct influence to the initiate risk of CVD, including deceased levels of blood glucose, total cholesterol, triglyceride, glycated serum protein, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol of mice in compared to control after 4 weeks of experiment.

Injection of α-galactooligosaccharides (α-GOS) showed a restrictive activity in reduced high-fat-diet (HFD)-induced metabolic syndrome in inhibited the content of all bacteria, such as Bacteroides in breaking down food and producing valuable nutrients and energy that the body needs and Lactobacillus with function in glucose metabolism and protect against over growth of pathogens in the digestive tract.

These illustration indicated that α-galactooligosaccharides (α-GOS) have a potential used as a probiotic to improve digestive health by balancing the levels of gut bacteria through colonic fermentation.

Furthermore, the extract also induced the production of short-chain fatty acids such as propionic acid with function in reduced acidity and butyric acids with function in reduced inflammation and improve overall gastrointestinal health through colonic bacterial fermentation.

Short-chain fatty acids has been extensively promoted as prebiotics and probiotics with an aimed at improving colonic and systemic health.

The finding information suggested that α-galactooligosaccharides (α-GOS) isolated from fermentable soluble fibers extracted of chickpea may affect the metabolic disorders and gut bacterial ecosystem in a positive way.

Additionally, 14 days of 2 single-center, double-blind, randomized, placebo-controlled trials, 88 overweight adults [50% men and 50% women; 18-60 y old; body mass index (in kg/m(2)): 25-28] were supplemented for 14 d with tea contained α-GOSs with different α-GOS dosages (6, 12, or 18 g α-GOSs/d), formulas (12 g α-GOSs/d with >80% of molecules with a degree of polymerization of 2, 3, or 4), or a control substance (glucose syrup), also suggested that regardless to the composition, tea contained α-GOSs treatment group demonstrated a significant in reduced appetite, reduced energy intake during lunch and dinner in compared to control.

In other word, injection of α-GOSs daily and regularly may have a long-term effect in induced weight loss and mitigated metabolic disorders.

Similarly, the investigation of the effects of frequent consumption (five cups/week over 8 weeks) of pulses (yellow peas, chickpeas, navy beans and lentils), in compared with counselling to reduce energy intake by 2093 kJ/d (500 kcal/d), on risk factors of the MetSyn in two groups (nineteen and twenty-one subjects, respectively) of overweight or obese (mean BMI 32·8 kg/m2) adults
2017], also found that at the end of the experiment, both diets expressed a reductions in energy intake, waist circumference, systolic blood pressure, glycosylated Hb (HbA1c) and glucose AUC and homeostasis model of insulin resistance (HOMA-IR) following a 75 g oral glucose load at weeks 1 and 8 with levels of HDL and C-peptide increased by 4·5 and 12·3 %, respectively in compared to decreased by 0·8 and 7·6 %, respectively, in the energy-restricted group.

C-peptide is a proinsulin molecule produced by the beta cells in the pancreas.

Interestingly, insulin area under curve was found to decrease in both females and males on the energy-restricted diet by 24·2 and 4·8 %, respectively, but on the pulse diet it decreased by 13·9 % in females and increased by 27·3 % in males.

After taking into account of other con founder, Dr.Mollard RC, the lead author said, "frequent consumption of pulses,...reduced risk factors of the metabolic syndrome and these effects were equivalent, and in some instances stronger, than counselling for dietary energy reduction".

Taken together, the information findings, suggested that chick pea with abundant fibers with direct effect in improved gut health and reduced high blood pressure, high blood sugar, abnormal cholesterol or triglyceride levels and promoted weigh loss through decrease appetite may be considered as a function food in ameliorated risk of metabolic syndrome, thus lowering the risk of heart disease, stroke and diabetes.

Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of α-Galactooligosaccharides from Chickpeas on High-Fat-Diet-Induced Metabolic Syndrome in Mice by Dai Z1, Lyu W2, Xie M1, Yuan Q1, Ye H1, Hu B1, Zhou L1, Zeng X1.(PubMed)
(2) Regular consumption of pulses for 8 weeks reduces metabolic syndrome risk factors in overweight and obese adults by Mollard RC1, Luhovyy BL, Panahi S, Nunez M, Hanley A, Anderson GH.(PubMed)
(3) α-Galacto-oligosaccharides Dose-Dependently Reduce Appetite and Decrease Inflammation in Overweight Adults by Morel FB1, Dai Q2, Ni J3, Thomas D4, Parnet P5, Fança-Berthon P6.(PubMed)

Alternative Therapy, Yoga, an Integrated Form of Physical Exercise in Ameliorated Psychological Health in Women with Stillbirth

Kyle J. Norton 

Yoga may be used as integrated form of intervention in improved mental and physical health of  women who lost their babies due to stillbirth, some studies suggested.

Stillbirth is one of the tragic event to the mother characterized by the the death or loss of a baby before or during delivery.

Yoga, the ancient practice for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been well known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In the study to evaluate women in ages 19 and 45 experienced stillbirth within one year of the study, through online survey related to 1) pregnancy and family information (i.e., time since stillbirth, weight gain during pregnancy, number of other children) 2) physical activity participation, 3) depressive symptomatology, and 4) demographics, researchers found that over 88% reported of depression with score of >10 on depression scale and 23% stillbirth mothers who participated yoga  practice displayed an improvement of greater than 58% in reduction in depression.

In compared to control, decreased symptoms of depression also were observed in the group engaging to yoga exercise.

The findings indicated that yoga practice may serve as an unique opportunity to help women to cope with the multiple mental sequelae after stillbirth.

Additionally, in the concern of increased risk of post-traumatic stress disorder (PTSD) and depressive symptoms in women who experience stillbirth, researchers at the Arizona State University conducted a study to investigate whether yoga as a strategy can help to cope with PTSD symptoms of  women who have experienced the death of their baby. Out of 26 women in each group completed randomly assigned to either > 3 wks of yoga, or < 3 wks of yoga) researchers found that regardless to the periods of participation, 75% of women in both groups expressed that yoga intervention was very enjoyable or enjoyable, and very helpful or helpful to cope with grief.

Truly, yoga breathing exercise induced  deep relaxation and meditation showed to induce a state of consciousness to cope with psychological stress caused by grief and unfortunate of present event by facing the loss with the positive feelings in reduced anger and increased more compassion towards the body and mind. Physically, the mental expression in the right direction in yoga intervention  eventually induced the returning of proper hormone secretion.

Karla Helbert, LPC. Therapist, Certified Yoga instructor, in the article of Yoga for Grief & Loss. recommended yoga asanas and practices for the relief and release of grief opening poses such as mountain pose, sun salutation, yogic eye movements to help to "establish a ritual and energize the body and mind", "counteract feelings of depletion and sadness" and "(encounter) processing thoughts and memories of traumatic grief".

In deed, women in both groups of the study also indicated a higher levels of satisfaction and perceptions

More importantly, participation of 6-week and 12-month follow-up assessments among women with a history of stillbirth (N = 22) also indicated an improvement of negative psychosocial symptoms and reduced levels of perinatal grief in four of the five facets of mindfulness.

Impressively, mindfulness-based stress reduction (MBSR) is an yoga intervention which has been found to exert a significant effect in increased functional self-insight and quality of life, improved emotional balance and coping with distress, induced decreased state and trait anxiety, depression  total mood disturbance, particularly in restored balance between affective and sensory neural networks.

Dr. Roberts LR, the led author said after taking second look of the results, " Yoga mindfulness was significant mental health needs,......... following stillbirth, (as the program) successfully addressed by a promising MBI with potential scalability and sustainability"

Taking altogether, yoga as a safe and low cost may be considered as an integrated form of physical and mental exercise used conjunction with primary treatment  in reduced psychological symptoms in women after having stillbirth.


For More information of yoga lessons tailor to a complete well being for women, please visit: YOGA BURN


Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Physical activity and depressive symptoms after stillbirth: informing future interventions by Huberty J1, Leiferman JA2, Gold KJ3,4, Rowedder L5, Cacciatore J6, McClain DB7.(PubMed)
(2) Experiences of women who participated in a beta-test for an online-streamed yoga intervention after a stillbirth by Huberty JL1, Matthews J1, Leiferman J2, Cacciatore J3.(PubMed)
(3) Mindfulness-Based Intervention for Perinatal Grief in Rural India: Improved Mental Health at 12 Months Follow-Up by Roberts LR1, Montgomery SB2.(PubMed)
(4) Mindfulness-based Intervention for Perinatal Grief after Stillbirth in Rural India by Lisa R. Roberts, DrPH, MSN and Susanne B. Montgomery, PhD, MPH(PubMed)

Tuesday 12 December 2017

Food Therapy: Chickpeas Isoflavones Genistein In Reduced Risk and Treatment of Prostate Cancer

Kyle J. Norton


Chickpeas with abundant isoflavones genistein may have a therapeutic and profound effect in reduced risk and treatment of prostate cancer, some scientists suggested.

Garbanzo bean also known as chickpea is an edible legume of genus Cicer and the family Fabaceae, high in protein and minerals. It is one of the earliest cultivated vegetables, native to Middle East.

Prostate cancer is a medical condition characterized by cells growth uncontrollably in the prostate tissues. At the later stage, the cancerous may infect the tissues and organs distance away from the site of origin.

The investigation of the effects of isoflavone genistein isolated from chickpeas in prostate cancer risk was found to associate to various expressions and mechanisms.

Reactive oxygen species ROS was studied intensively for the duo effects in inhibited cancer development and induced cancer cell apoptosis through cytotoxicty.

On one hand, over expression of ROS with low antioxidant levels may cause cellular damage and induce alternation of DNA transcript being transmitted by mRNA through a complex passage to initiate irregular cell growth, the early stage of cancer development.

On the other hand, over expression of ROS can cause cytotoxicity to the target cancer site in induction of cells death and apoptosis.

Isoflavone genistein isolated from chickpeas was found to exert significantly antioxidant effects on human cells, thus ameliorated oxidative damage to cellular DNA in initiation of cancer development.

Injection of isoflavone genistein to normal cell acted as free radical scavengers not only improved the antioxidants status in inhibited the ROS activity in inauguration and progression of multistage carcinogenesis but also reduced the expression of oxidative stress-response related genes.

Interestingly, such injection also enhanced the over expression ROS function in causing toxicity to cancer cells without harming the nearby healthy cells, thus increasing cancer cells degradation, subsequently in cells death.

In fact, isoflavone genistein, best known as natural tyrosine kinase inhibitor (TKIs) are a class of chemo-medicine with function in inhibited, or blocked, the enzyme tyrosine kinase in induction of apoptosis in several different types of cancers, including prostate cancer.

Further analysis of the effect of isoflavone genistein adminitration also indicated that the phytochemicals induced cancer cell apoptosis by increased expression of Bax protein in suppressed the production of pro apoptotic activity in the cancerous site.

Additionally, isoflavone genistein also demonstrated a significant effect in stimulated the p21, a potent cyclin-dependent kinase inhibitor (CKI) expression in promoted cancer cell cycle arrest.

Application of the phytochemicals also decreased anti apoptotic activities of Bcl-2 and BclXL by blocking the release of mitochondrial contents for enhanced cell division.

More importantly, in the regulation of cellular apoptosis, isoflavone genistein also activated the PARP protein and caspases enzyme with functions to programmed cell death.

Moreover, further evaluation of cancer cell apoptosis due to injection of isoflavone genistein, researchers at the Second Affiliated Hospital of Xi'an Jiaotong University postulated that in the process in induced cancer cell apoptosis, isoflavone genistein also inhibited NF-κB protein in regulated and controlled transcription of DNA, and cell survival in numbers of cancer, examined by the electrophoresis mobility shift assay (EMSA)

In fact, the expression of NF-κB protein in reduced cancer cell proliferation and site expansion was attributed to the activation of hydrogen peroxide H2O2, with function of cytotoxicity to the tumor and tumor necrosis factor (TNF-α), a cell signaling protein with function to initiate cellular apoptosis.

Taken together, isoflavones genistein may be effective in reduced risk and treatment of prostate cancer depending to some factors involving having or not having equol converting bacteria in the intestine, specific polymorphic variation in the region of the associated gene.



Arthritis Is Curable
You Can Eliminate Osteoarthritis
By addressing the Underlying Causes through Clinical Trials and Studies

Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months

Super foods Library, Eat Yourself Healthy With The Best of the Best Nature Has to Offer recommended by Kyle J. Norton

Back to Kyle J. Norton Home page http://kylejnorton.blogspot.ca

Author Biography
Kyle J. Norton, Master of Nutrients
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Induction of Cancer Cell Death by Isoflavone: The Role of Multiple Signaling Pathways by Yiwei Li, Dejuan Kong, Bin Bao, Aamir Ahmad, and Fazlul H. Sarkar(PMC)
(1) Chickpea (Cicer arietinum) and other plant-derived protease inhibitor concentrates inhibit breast and prostate cancer cell proliferation in vitro by Magee PJ1, Owusu-Apenten R, McCann MJ, Gill CI, Rowland IR.(PubMed)
(2) Protease inhibitors: possible anticarcinogens in edible seeds by Troll W, Wiesner R.(PubMed)
(4) Isoflavones and Prostate Cancer: A Review of Some Critical Issues by Hong-Yi Zhang,1,2 Jie Cui,3 Ye Zhang,2 Zhen-Long Wang,1 Tie Chong,1 and Zi-Ming Wang1(PMC)
(5) Induction of Cancer Cell Death by Isoflavone: The Role of Multiple Signaling Pathways by Yiwei Li, Dejuan Kong, Bin Bao, Aamir Ahmad, and Fazlul H. Sarkar(PMC)

24 Exceptional Health Benefits of Beet or Beet Root

By Kyle J. Norton

Beet, best known as the beetroot or garden beet  is a perennial plant with leafy stems growing to 1–2 m tall, belongings to the amaranth family,

24 Health Benefits of Beet or Beet Root
1. Beet (Beta vulgaris) and Cancers
2. Beet (Beta vulgaris) and Type 2 diabetes
3. Beet (Beta vulgaris) and Hypertension
4. Beet (Beta vulgaris) as antioxidants
5. Beet (Beta vulgaris) and Cardiovascular diseases
6. Food Therapy: Beet Juice, the Best Beverage for Reduced Risk and Treatment of Breast Cancer
7. Food Therapy: Beet, the Best in Balancing Endothelial Function
8. Food Therapy: Beet, A Potent in Attenuated Risk and Anti Skin Cancer Biomedical Whole Food
9. Food Therapy, Beet, the Potent Anti Platelet Aggregation Whole Food Medicine
10. Food Therapy: Beet, in Prevention and Treatment of Colon Cancer
11. Food Therapy: Beet, a functional Food in Reduced Risk and Treatment of Parkinson's disease(PD)
12. Food Therapy: Beet, The Best Anti Liver Cancer Natural Functional Food
13. Food Therapy: Beet, the Best functional Food in Exhibited Hepatoprotective Effects
14. Food Therapy: Whole food Beet or Beet Juice In Promotion of Brain Health
15.***** Foot Therapy: Beet, The Best Anti Hypertension Functional Food
16. Food Therapy: Beet or Dietary Nitrate-rich Beetroot Juice in Reduced Risk of Hyperlipidemia
17. Food Therapy: Beet, The Best in Prevention and Treatment of Bladder Cancer
18. Food Therapy: Beet or Beetroot, A Function Food in Reduced Risk and Treatment of Inflammatory Bowel Disease
19. Food Therapy: Beet or Beet Root, The Best Anti Inflammatory Functional Food
20. Food Therapy: Beet or Beet Root, the Function Food in Prevention and Treatment of Prostate Cancer
21. Food Therapy: Beet or Beet Root, The Best in Ameliorated Oxidative Stress
22. Dietary Nitrate-Rich Beetroot Juice Improved Vascular Function In Reduced Risk of Heart Disease
22. Food Therapy: Beet Juice May be Potent Function Foods For Reduced Risk and Treatment of Pharynx Cancer
23. Food Therapy: Beet, The Best anti inflammatory functional Food
24. Food Therapy: Beet, Reduces Risk of Insulin Resistance and Early Onset of Diabetes


Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Monday 11 December 2017

Food Therapy: Beet, Reduces Risk of Insulin Resistance and Early Onset of Diabetes

Kyle J. Norton


Beet juice containing phytochemicals may alter postprandial glucose and insulin responses in prediabetics, some scientists postulated.

Insulin resistance, a condition of not providing enough insulin to counter the rise of blood glucose is considered as the early progression of onset of diabetes.

Beet, best known as the beetroot or garden beet is a perennial plant with leafy stems growing to 1–2 m tall, belonging to the amaranth family,

Investigation of the efficacy of beet in ameliorated risk of insulin resistance may be associated different aspects involved numbers of mechanisms.

In a total of sixteen healthy individuals recruited, with consumed test meals in a controlled single-blind cross-over design, intake of beet juice showed a remarkable in countering the glucose uptake of glucose.

Tested subject reveled a significant lowering of the postprandial insulin response in the early phase and a significantly lower glucose response in the 0–30 min phase in compared to control fed with control beverage matched for macronutrient content (MCON).

Further analysis indicated that beet juice attenuated rise of glucose in the blood stream may be attributed to constituent of betacyanin betalain pigments which have been found to process anti glucose uptake and insulin resistance in patients with diabetes and other metabolic diseases and function of phytochemical polyphenols in stimulated insulin secretion and reduced hepatic glucose output by inhibited α-amylase, α-glucosidase and glucose absorption in the intestine.

α-Amylase is a protein enzyme having a function to convert hydrolysis of starch into sugars.
α-glucosidase is glucosidase in the small intestine with function to break down starch and disaccharides to sugars.

Additionally, in the homeostasis model assessment-insulin resistance index, dietary nitrate from beet juice also showed a lower insulin resistance in test subjects in compared to control through regulation of glucose homeostasis and insulin signaling pathway, improvement of insulin resistance and lipid homeostasis, inflammation, and endothelial function.

Dr. Peter C, the lead researcher said, "Betalains, polyphenols and dietary nitrate found in the beetroot juice may each contribute to the observed differences in the postprandial insulin concentration".

Interestingly, in comparison the effect of ingredients of combined 100 ml black tea, beetroot juice or control (water) in 16 obese, insulin-resistant males, beetroot juice plus black tea and beet juice treated groups exhibited a decreased postprandial peripheral vascular resistance (VR) in resistance vessels, but lesser than black tea, in compared to other groups.

According to further examination, the efficacy of beet juice and black tea expressed a significant in attenuated insulin resistance was attributed to increased postprandial blood flow in induced glucose disposal and decreased postprandial insulin response by 29 %..

More profoundly, in standardized breakfasts with or without beet-fibre given, in random order, to non-insulin-dependent diabetics study, beet fiber intake individuals expressed a strong effect in rate of glucose decrease after the meal.with blood glucose levels monitored continuously and hormonal responses determined at regular intervals for 3 hr.

Both tested subjects did not exert notable differences with regard to the plasma levels of insulin, C-peptide or glucagon in regulated levels of blood glucose,

C-peptide is a substance involved proinsulin molecule produced by the beta cells in the pancreas.

According to the study, the over expression of levels of somatostatin, a growth hormone–inhibiting hormone induced by beet-fibre intake.may contribute to a potential effect in diminished glycemic response through reduced glucose absorption and a delayed gastrointestinal transit time.

The collective findings may provide a footage of using beet juice as a functional food in ameliorated risk of insulin resistance and prevented early onset of diabetes.


Author Biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Effects of a beetroot juice with high neobetanin content on the early-phase insulin response in healthy volunteer by Peter C. Wootton-Beard,1 Kirsten Brandt,2 David Fell,3 Sarah Warner,1,2 and Lisa Ryan1,4,*(PMC)
(2) Impact of flavonoid-rich black tea and beetroot juice on postprandial peripheral vascular resistance and glucose homeostasis in obese, insulin-resistant men: a randomized controlled trial by Fuchs D1, Nyakayiru J2, Draijer R1, Mulder TP1, Hopman MT2, Eijsvogels TM2, Thijssen DH3.(PubMed)
(3) Reduced glycemic response to beet-fibre meal in non-insulin-dependent diabetics and its relation to plasma levels of pancreatic and gastrointestinal hormones by Hagander B, Asp NG, Efendić S, Nilsson-Ehle P, Lungquist I, Scherstén B.(PubMed)
(4) Purified Betacyanins from Hylocereus undatus Peel Ameliorate Obesity and Insulin Resistance in High-Fat-Diet-Fed Mice by Song H1, Chu Q1, Xu D1, Xu Y1, Zheng X1.(PubMed)
(5) Beneficial effects of inorganic nitrate/nitrite in type 2 diabetes and its complications by Bahadoran Z1, Ghasemi A2, Mirmiran P3, Azizi F4, Hadaegh F5.(PubMed)

Food Therapy: Beet, The Best anti inflammatory functional Food

Kyle J. Norton

Intake of beet juice may have a reduced effect of inflammation through suppressing production of pro inflammatory cytokines produced by immunity.

Inflammation is the reaction of immune system in protected our body against foreign invasion cause of infection or tissues damage.

Beet, best known as the beetroot or garden beet is a perennial plant with leafy stems growing to 1–2 m tall, belonging to the amaranth family,

Intake of raw beet juice (RBJ) and cooked beet (CB) on BP of hypertensive subjects, showed a significant improvement of inflammation through regulating the cell signal protein in initiation of systemic inflammation involved in acute phase of inflammatory cytokine tumor necrosis factor alpha (TNF-α) and reducing high-sensitivity level of C-reactive protein (hs-CRP) which have a major effect in the onset of cardiovascular risk in both tested groups.

Although the reduced blood pressure is not sustainable in tested subjects after creasing intake of raw beet juice (RBJ) and cooked beet (CB), the improvement of endothelial function as a result of the presence of nitric oxide and systemic inflammation during the test are remarkable.

Endothelial dysfunction is a major risk factor of cardiovascular disease and precedes the development of atherosclerosis.

In muscle damage following a marathon of 30 recreationally active males, using a double blind, independent group design with doses of beetroot juice (H-BT; 250 ml), a lower dose of beetroot juice (L-BT; 125 ml), or an isocaloric placebo (PLA; 250 ml) immediately (×3 servings), oral administered beet juice groups, showed a faster recovery of muscle damage at 48 hours in compared control.

Further analysis, application of beetroot juice in any dose enhanced over expression of antioxidants induced recover of muscle damage not only was attributed to the juice function in reduced high-sensitivity level of C-reactive protein (hs-CRP) but also increased modulation of enzyme creatine kinase (CK) responsible in expression by various tissues and cell types during muscle damage.

The antioxidant effects of beet juice also displayed a significant activity in reduced gene interleukin-6 (IL-6) secreted by T cells and macrophages in production of pro inflammatory cytokine to induce the acute phase of inflammation caused by muscle damage and exhibited anti inflammatory mytokines in fighting against infection.

Additionally, administration of beetroot juice inhibited the release of neutrophils and regulated gene interleukin-8 (IL-8), a chemoattractant cytokine produced by a variety of tissue and blood cells in expression of inflammation in the site of damage.

Neutrophils is a type of immune cells released to site of infection by immunity. Over expression of  neutrophils normally are an indication of acute infection.

Taking altogether, beet juice and products may have a remarkable effect in reduced risk of over inflammatory expression of immune system when come to muscle damage and infection caused by microorganisms.


Author biography
Kyle J. Norton(Scholar, Master of Nutrients), all right reserved.
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Improvement of hypertension, endothelial function and systemic inflammation following short-term supplementation with red beet (Beta vulgaris L.) juice: a randomized crossover pilot study by Asgary S1, Afshani MR2, Sahebkar A3,4, Keshvari M1, Taheri M5, Jahanian E6, Rafieian-Kopaei M7, Malekian F8, Sarrafzadegan N1.(PubMed)
(2) The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise by Clifford T1, Bell O2, West DJ2, Howatson G2,3, Stevenson EJ2.(PubMed)

Sunday 10 December 2017

Alternative Therapy: Yoga, The best in Ameliorated Prenatal Chronic Poor Sleep In Risk of Pregnancy Outcomes

Kyle J. Norton 


Some pregnant women may experience sleep disturbance. Yoga as integrated form of intervention may have a profound effect in treatment of this syndrome through expression in reduction of related potential pathophysiological mechanisms, some scientists studies suggested.

Yoga, the ancient practical technique for harmonized external and internal body well beings, through breath control, meditation, bodily movement and gesture..... has been best known for people in Western world and some parts in Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.

In a study to review the clinical evidence of the association between conditions of sleep loss during pregnancy and adverse pregnancy outcomes researchers at the joint study led by the University of Pisa, through papers published between January 1, 1960 and July 2013, suggested that chronic sleep loss frequently throughout the course of pregnancy may contribute to adverse pregnancy outcomes.
and chronic sleep loss during pregnancy as a result of stress and a physiological stressor per se, may also lead to stress 'overload' which has a negative in influence in pregnancy outcome.

Yoga exercise involved stretching, meditation and relaxing of muscles expressed a significant improvement of psychological arouses such as calmness, relaxation, reduced stress and promoted
physical and mental exertion may lead to less sleep latency, less sleep disturbances, and better sleep pattern.
Additionally, Yoga breathing exercises has shown to improve oxygen saturation through enhancing the strength of the lung muscles, thus increasing blood circulation which can be a positive factor in reduced sleep disorders like sleep apnea.

Further analysis, increased blood flow to the brain may improve brain cells in transfer and receive information properly, thus reducing risk of psychological tension which may have a negative influence the sleep efficiency.

Habitual snoring and obstructive sleep apnea, restless legs syndrome and insomnia were 3 common syndromes in pregnancy of breathing-related sleep disorders.

The investigation of whether sleep quality during the second and third trimesters of pregnancy have any effect to obstetric-neonatal outcomes, postulated that the incidence of poor sleep quality was found in 58% for second-trimester participants and 66% for third-trimester participants and women who experience third-trimester poor sleepers were more likely to have had a vacuum-assisted delivery.

Pregnancy influences to hormone change and increased trips to bathroom at night caused by early pregnancy systems may have a profound impact to induce poor sleep in first trimester.

Also, in third trimester, pregnant women may experience fewer periods of deep sleep and wake up more often during the night due to more trips to the bath as result of the growing baby putting pressure on the bladder. Reduced intake of fluid few hours before bed time may be helpful. Some women may also experience heartburn, leg cramps, restless leg syndrome, and snoring which may cause them awake during night sleep.

Indeed, snoring increases the chances of sleep disturbances by two fold was reported in some studies.

And snoring may be another indication of poor sleep pattern, yoga breathing improved the sleep efficiency by enhancing muscles of the throat, lung and strengthen the muscles of air flow passage reducing risk of obstructed nasal airways.

According to the University of Colorado Denver, sleep disorders are common in pregnancy and have maternal and fetal consequences if left untreated. Yoga breathing exercises might have beneficial effect by strengthening upper airway muscles resulting in less sleep disturbances observed in this population

Additionally, sleep disorders also were associated to adverse pregnancy outcomes including preeclampsia, elevated serum glucose, depression, prolonged labor, and cesarean birth.

After taking into account of other risk factors, Dr. Nodine PM, the led author said, " sleep disorders of pregnancy, elucidates their relationship with maternal and neonatal outcomes, and presents current evidence regarding diagnostic and management strategies".

Yoga is a well-tolerated and safe mode of exercise with promising in improving sleep disturbance and reduced day and night time symptoms of sleep disorders during pregnancy including excessive daytime sleepiness, difficulty falling asleep, difficulty staying asleep, and waking up too early.

Taking altogether, there is no doubt that chronic poor sleep during pregnancy may induce a negative outcome in both mother and newborn.

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Author Biography
Kyle J. Norton (Scholar, Master of Nutrients, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published on line, including world wide health, ezine articles, article base, healthblogs, selfgrowth, best before it's news, the karate GB daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as international journal Pharma and Bio science, ISSN 0975-6299.

Sources
(1) Chronic sleep loss during pregnancy as a determinant of stress: impact on pregnancy outcome by Palagini L1, Gemignani A2, Banti S3, Manconi M4, Mauri M3, Riemann D5.(PubMed)
(2) The association between prenatal sleep quality and obstetric outcome by Hung HM1, Ko SH, Chen CH.(PubMed)
(3) Common sleep disorders: management strategies and pregnancy outcomes by Nodine PM1, Matthews EE.(PubMed)