Kyle J. Norton
Herbal Aloe Vera may have a potential effect in lowering insulin resistance, the main cause of type II diabetes, some scientists suggested
Diabetes is a chronic condition caused by insufficient insulin entering the bloodstream to regulate glucose.
In other words, diabetes is either caused by cells in the pancreas dying off or receptor sites clogged up by fat and cholesterol.
In some cases, diabetes is also caused by allergic reactions of cells in the immune system.
According to the statistic provided by the International Diabetes Federation, 425 million people have diabetes in the world and 159 million people in the Western Pacific Region.
Sadly, according to the prediction, by 2045 people infected by diabetes will rise to 183 million.
There were over 3.492.600 cases of diabetes in Malaysia in 2017.
Type 1 diabetes is a condition caused by the immune system mistakenly attacking and destroying the insulin-producing beta cells of the pancreas.
The actual causes of type 2 diabetes are unknown. However, researchers do know that genetic mutation and unhealthy diet and lifestyle are major risk factors for insulin resistance, the most common cause of type 2 diabetes.
Lisa M. Leontis RN, ANP-C, and Amy Hess-Fischl in the article explaining Type 2 Diabetes Causes -
Genetics and Lifestyle Choices Play a Role wrote, " Two people have the same genetic mutation. One of them eats well, watches their cholesterol, and stays physically fit, and the other is overweight (BMI greater than 25) and inactive. The person who is overweight and inactive is much more likely to develop type 2 diabetes because certain lifestyle choices greatly influence how well your body uses insulin".
These results suggested that by keeping your body fit and active accompanied by a healthy diet, one can totally prevent the onset of insulin resistance, the main cause of type 2 diabetes, regardless of other risk factors.
Aloe Vera is species of succulent plant in the genus Aloe, belongings to the Family Xanthorrhoeaceae, native to Sudan cultivated around the world in suitable climate regions for commercial profits due to its health benefits.
Aloe vera has been used in herbal medicine in treating many kinds of diseases, including wounds, burn healing, minor skin infections, sebaceous cysts, diabetes, and elevated cholesterol, etc. It is also one of many popular herbs studied in scientific ways with some conflicting results
The Ingredients The ten main areas of chemical constituents of Aloe vera include amino acids, anthraquinones, enzymes, minerals, vitamins, lignins, monosaccharides, polysaccharides, salicylic acids, saponins, and sterols.
In the study of PCOS induced in Charles Foster female rats by oral administration of non-steroidal aromatase inhibitor letrozole (0.5 mg/kg body weight, 21 days), before administration of herbal Aloe vera, researchers found that all rats exhibits hyperglycemic and 90% of them also showed elevated plasma triglycerides, elevated LDL cholesterol levels, and lowered plasma HDL cholesterol levels indicative of a dyslipidemic profile.
After injection of An AVG formulation (1 ml (10 mg)/day, 30 days) orally, in selected rats with PCOS positive rats with an aberrant lipid profile, researchers showed that* AVG-treated PCOS rats exhibited a significant reduction in plasma triglyceride and LDL cholesterol levels, with an increase in HDL cholesterol.
* The gel treatment also caused a reversion of abnormal estrous cyclicity, glucose intolerance, and lipid metabolizing enzyme activities, bringing them to normal.
These results suggested that AVG processes phyto components with anti-hyperlipidemic effects and it has shown efficacy in the management of not only PCOS but also the associated metabolic complication of dyslipidemia.
Further to confirm Aloe vera anti-insulin resistance effect induction of type 2 diabetes, researchers at the University of Exeter conducted a review of literature from the database in MEDLINE, EMBASE, Biosis, and the Cochrane Library.
10 selected studies suggest that oral administration of aloe vera might be a useful adjunct for lowering blood glucose in diabetic patients as well as for reducing blood lipid levels in patients with hyperlipidemia.
The topical application of aloe vera was not an effective substance in preventative for radiation-induced injuries. However, the application might be effective for genital herpes and psoriasis.
Moreover, in the animal model examine the effects of processed Aloe vera gel (PAG) on the course of established diet-induced non-insulin-dependent diabetes mellitus (NIDDM) in C57BL/6J mice fed with the high-fat diet.
Before injection of Aloe vera gel (PAG), mice exhibited diet-induced obesity (DIO) with blood glucose levels above 180mg/dl, after administrating PAG for 8 weeks, researchers showed that
* Aloe vera gel (PAG) exerts a strong effect in reducing circulating blood glucose concentrations to a normal level in these DIO mice.
* The administration of PAG significantly decreased plasma insulin.
Additionally, PAG antidiabetic effects were confirmed by intraperitoneal glucose tolerance testing. PAG injection also appeared to lower blood glucose levels by decreasing insulin resistance.
Dr. Kim K, the lead author of the final report, wrote, "The oral administration of PAG prevents the progression of NIDDM-related symptoms in high-fat-diet-fed mice, and suggests that PAG could be useful for treating NIDDM".
Taken together, herbal aloe vera gel may be considered a functional food in decreasing insulin resistance and preventing the onset of type 2 diabetes.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299
References
(1) Aloe barbadensis Mill. formulation restores lipid profile to normal in a letrozole-induced polycystic ovarian syndrome rat Model (PubMed)
(2) Aloe vera: a systematic review of its clinical effectiveness. by Vogler BK, Ernst E.(PubMed)
(3) Hypoglycemic and hypolipidemic effects of processed Aloe vera gel in a mouse model of non-insulin-dependent diabetes mellitus. by Kim K, Kim H, Kwon J, Lee S, Kong H, Im SA, Lee YH, Lee YR, Oh ST, Jo TH, Park YI, Lee CK, Kim K.(PubMed)
Health Researcher and Article Writer. Expert in Health Benefits of Foods, Herbs, and Phytochemicals. Master in Mathematics & Nutrition and BA in World Literature and Literary criticism. All articles written by Kyle J. Norton are for information & education only.
Pages
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Friday, 30 June 2023
#CruciferousVegetables Decrease the Risk of #ProstateCancer, Particularly in Men With Mutation of Genes GSTM1 and GSTT1, Researchers Say
Kyle J. Norton
Cruciferous vegetables may be considered as the next plants, processing pharmaceutical value in the extraction of single-ingredient chemo medicine of blocking the onset of prostate cancer, some scientists suggested
Prostate cancer is a condition characterized by irregular and uncontrollable growth of the cells of the prostate. In the advanced stage, the cancerous cells can spread to distant parts of the body through blood and fluid circulation.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
According to a statistic provided by the Canadian government, 1 in 7 men will develop prostate cancer during their lifetime, and 1 in 27 will die of it.
Sadly, out of 4 men diagnosed with prostate cancer, 1 will die of it. which is very similar to the ratio observed for breast cancer in women.
A diagnosis of prostate cancer carries a significant burden of induction of significant anxiety and depression.
Researchers do not know the exact causes of prostate cancer and can not explain why some men who do process inherited gene mutation are susceptible to the onset of prostate cancer while others do not.
But they do know that some risk factors such as age, family history, race, and diet are associated with the development of prostate cancer.
Early-diagnosed prostate cancer patients have a 5-year survival rate of nearly 100% with 98% of these patients still alive after 10 years compared to the 5-year survival rate of the advanced stage of 30%.
Therefore, if you are at a high risk of the prostate cancer development group, please make sure that you have your prostate gland checked every year.
Cruciferous vegetables are a group of vegetables including cauliflower, cabbage, cress, bok choy,..... and broccoli.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae.
The healthy veggie has large flower heads, usually green in color and a mass of flower heads, surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
Epidemiologically, chemical constituents of cruciferous vegetables, such as broccoli have been shown to decrease the incidence of prostate cancer.
In the finding of broccoli effect in the genetic implication of risk of prostate cancer, researchers at the Institute of Food Research conducted a study that includes
volunteers with or without genetic mutation of glutathione S-transferase mu 1 (GSTM1) positive and null.
Glutathione S-transferase (GST) is a detox enzyme with a function involving the detoxification of many potentially carcinogenic compounds.
Participants were randomly assigned to six months of either a broccoli-rich or a pea-rich diet.
At the end of the study, researchers found that
* Pea-rich diet shows no differences in gene expression between glutathione S-transferase mu 1 (GSTM1) positive and null individuals
* Broccoli-rich diet group exerts significant differences between GSTM1 genotypes associated with transforming growth factor beta 1 (TGFbeta1) and epidermal growth factor (EGF) signaling pathways.
* Both diets demonstrate significant androgen signaling.
* Men on the broccoli diet had additional changes to mRNA processing, and TGFbeta1, EGF, and insulin signaling.
The growth factor beta (TGFbeta) signaling pathway is a key role in tumor suppression through modulating processes such as cell invasion, immune regulation, and microenvironment modification normally. However, the transforming growth factor-beta (TGF-beta) signaling pathway can cause tumor development with similar physio activity.
In healthy and malignant cells, epidermal growth factor receptor (EGFR) allows cells to grow and divide
These results suggested that broccoli interacts processed a strong anti-prostate cancer effect in patients with the GSTM1 genotype associated with inflammation and carcinogenesis in the prostate gland.
Dr. Traka M, the lead author after taking into account other factors, said, "Diets rich in cruciferous vegetables may reduce the risk of prostate cancer and another chronic disease".
Furthermore, in a population-based, case-control study of prostate cancer, including 428 men with incident prostate cancer and 537 community controls with genotyping for deletions in GSTM1 and GSTT1 performed in a subset of men who provided blood, researchers found that
* Intake of cruciferous vegetables, such as broccoli, the greatest source of sulforaphane, is associated with decreased prostate cancer risk at all levels compared to the lowest consumers.
* Intake of cruciferous vegetables also displays a significantly reduced risk of prostate cancer in men with a mutation of gene GSTM1. Particularly in the high broccoli intake group.
The finding suggested that 2 or more servings per month of cruciferous vegetables may reduce the risk of prostate cancer, especially among men with GSTM1-present alleles.
At the final of the experimental report, Dr. Joseph MA, the lead scientist, wrote, "(These results) are consistent with a role of dietary ITCs as chemopreventive agents against prostate cancer.
The depletion of the gene of the GSTM1 genotype of Glutathione S-transferase (GST) enzymes may be associated with an increased risk of cancer as this depletion reduced the function of GST in detoxifying most potentially carcinogenic compounds.
Taken altogether, cruciferous vegetables may be considered as a functional food in the promoted expression of detoxified enzymes to prevent the onset of prostate cancer, especially in men with the genetic mutation gene GSTM1.
.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Reference
(1) Broccoli consumption interacts with GSTM1 to perturb oncogenic signaling pathways in the prostate by Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, Frost V, Chantry A, Jones AM, Ortori CA, Barrett DA, Ball RY, Mills RD, Mithen RF. (PubMed)
(2) Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk by Joseph MA, Moysich KB, Freudenheim JL, Shields PG, Bowman ED, Zhang Y, Marshall JR, Ambrosone CB. (PubMed)
(3) Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells by Abdulah R, Faried A, Kobayashi K, Yamazaki C, Suradji EW, Ito K, Suzuki K, Murakami M, Kuwano H, Koyama H.(PubMed)
Cruciferous vegetables may be considered as the next plants, processing pharmaceutical value in the extraction of single-ingredient chemo medicine of blocking the onset of prostate cancer, some scientists suggested
Prostate cancer is a condition characterized by irregular and uncontrollable growth of the cells of the prostate. In the advanced stage, the cancerous cells can spread to distant parts of the body through blood and fluid circulation.
Most prostate cancers are slow-growing and enlarged prostate and prostate cancer may be detected during physical (rectum) exams.
According to a statistic provided by the Canadian government, 1 in 7 men will develop prostate cancer during their lifetime, and 1 in 27 will die of it.
Sadly, out of 4 men diagnosed with prostate cancer, 1 will die of it. which is very similar to the ratio observed for breast cancer in women.
A diagnosis of prostate cancer carries a significant burden of induction of significant anxiety and depression.
Researchers do not know the exact causes of prostate cancer and can not explain why some men who do process inherited gene mutation are susceptible to the onset of prostate cancer while others do not.
But they do know that some risk factors such as age, family history, race, and diet are associated with the development of prostate cancer.
Early-diagnosed prostate cancer patients have a 5-year survival rate of nearly 100% with 98% of these patients still alive after 10 years compared to the 5-year survival rate of the advanced stage of 30%.
Therefore, if you are at a high risk of the prostate cancer development group, please make sure that you have your prostate gland checked every year.
Cruciferous vegetables are a group of vegetables including cauliflower, cabbage, cress, bok choy,..... and broccoli.
Broccoli is a mustard/cabbage plant, belongings to the family Brassicaceae.
The healthy veggie has large flower heads, usually green in color and a mass of flower heads, surrounded by leaves and evolved from a wild cabbage plant on the continent of Europe.
Epidemiologically, chemical constituents of cruciferous vegetables, such as broccoli have been shown to decrease the incidence of prostate cancer.
In the finding of broccoli effect in the genetic implication of risk of prostate cancer, researchers at the Institute of Food Research conducted a study that includes
volunteers with or without genetic mutation of glutathione S-transferase mu 1 (GSTM1) positive and null.
Glutathione S-transferase (GST) is a detox enzyme with a function involving the detoxification of many potentially carcinogenic compounds.
Participants were randomly assigned to six months of either a broccoli-rich or a pea-rich diet.
At the end of the study, researchers found that
* Pea-rich diet shows no differences in gene expression between glutathione S-transferase mu 1 (GSTM1) positive and null individuals
* Broccoli-rich diet group exerts significant differences between GSTM1 genotypes associated with transforming growth factor beta 1 (TGFbeta1) and epidermal growth factor (EGF) signaling pathways.
* Both diets demonstrate significant androgen signaling.
* Men on the broccoli diet had additional changes to mRNA processing, and TGFbeta1, EGF, and insulin signaling.
The growth factor beta (TGFbeta) signaling pathway is a key role in tumor suppression through modulating processes such as cell invasion, immune regulation, and microenvironment modification normally. However, the transforming growth factor-beta (TGF-beta) signaling pathway can cause tumor development with similar physio activity.
In healthy and malignant cells, epidermal growth factor receptor (EGFR) allows cells to grow and divide
These results suggested that broccoli interacts processed a strong anti-prostate cancer effect in patients with the GSTM1 genotype associated with inflammation and carcinogenesis in the prostate gland.
Dr. Traka M, the lead author after taking into account other factors, said, "Diets rich in cruciferous vegetables may reduce the risk of prostate cancer and another chronic disease".
Furthermore, in a population-based, case-control study of prostate cancer, including 428 men with incident prostate cancer and 537 community controls with genotyping for deletions in GSTM1 and GSTT1 performed in a subset of men who provided blood, researchers found that
* Intake of cruciferous vegetables, such as broccoli, the greatest source of sulforaphane, is associated with decreased prostate cancer risk at all levels compared to the lowest consumers.
* Intake of cruciferous vegetables also displays a significantly reduced risk of prostate cancer in men with a mutation of gene GSTM1. Particularly in the high broccoli intake group.
The finding suggested that 2 or more servings per month of cruciferous vegetables may reduce the risk of prostate cancer, especially among men with GSTM1-present alleles.
At the final of the experimental report, Dr. Joseph MA, the lead scientist, wrote, "(These results) are consistent with a role of dietary ITCs as chemopreventive agents against prostate cancer.
The depletion of the gene of the GSTM1 genotype of Glutathione S-transferase (GST) enzymes may be associated with an increased risk of cancer as this depletion reduced the function of GST in detoxifying most potentially carcinogenic compounds.
Taken altogether, cruciferous vegetables may be considered as a functional food in the promoted expression of detoxified enzymes to prevent the onset of prostate cancer, especially in men with the genetic mutation gene GSTM1.
.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Reference
(1) Broccoli consumption interacts with GSTM1 to perturb oncogenic signaling pathways in the prostate by Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, Frost V, Chantry A, Jones AM, Ortori CA, Barrett DA, Ball RY, Mills RD, Mithen RF. (PubMed)
(2) Cruciferous vegetables, genetic polymorphisms in glutathione S-transferases M1 and T1, and prostate cancer risk by Joseph MA, Moysich KB, Freudenheim JL, Shields PG, Bowman ED, Zhang Y, Marshall JR, Ambrosone CB. (PubMed)
(3) Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells by Abdulah R, Faried A, Kobayashi K, Yamazaki C, Suradji EW, Ito K, Suzuki K, Murakami M, Kuwano H, Koyama H.(PubMed)
#Herbal #Ginger Relieves Pain and Swelling by Exerting Anti Inflammatory Effect in #RheumaticDiseases, Researchers Find
Kyle J. Norton
Rheumatism is an autoimmune and inflammatory disease marked by inflammation and pain in the joints, muscles, or fibrous tissue, especially rheumatoid arthritis.
In other words, rheumatic diseases are medical and chronic conditions characterized by inflammation that affects your joints tendons, ligaments, bones, and muscles, including a group of diseases associated with arthritis.
Depending on the types of rheumatic diseases, conventional treatment may include medication for reducing the symptoms, physiotherapy, and stress management. The aim of the treatment is to alleviate pain and improve the quality of life. Sadly, none of the drugs has been found safe; all are known to produce mild to serious side effects.
The most common symptoms of rheumatic diseases are joint pain, and reduced motion in a joint, particularly, joint inflammation that induces swelling, and redness, on the affected area.
If you experience some of the above symptoms, you may have rheumatic diseases, please make sure you check with your doctor to rule out the possibility.
There is no single cause of rheumatic diseases. Researchers believe groups of factors such as genes and environmental influences may be associated with the onset of the diseases, including the increase in age, gender, family history, exposure to environmental toxic substances, and smoking.
However, the most common risk factor for rheumatic diseases in the Western world is obesity. Dr. the lead scientist, in the examination of the risk of obesity for the onset of rheumatic diseases, said, "The growing body of evidence recognizing the adipose tissue (AT) as an active endocrine organ secreting bioactive mediators involved in metabolic and inflammatory disorders, together with the global epidemic of overweight and obesity, rise obesity as a hot topic of current research".
" The chronic state of low-grade inflammation present in the obese condition and the multiple pleiotropic effects of adipokines on the immune system has been implicated in the pathogenesis of several inflammatory conditions including rheumatic autoimmune and inflammatory diseases".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient or whole food for the prevention and treatment of rheumatic autoimmune and inflammatory diseases with no side effects, scientists at Odense University examine the traditional use of ginger against rheumatism.
The study included 56 patients (28 with rheumatoid arthritis, 18 with osteoarthritis, and 10 with muscular discomfort) randomly assigned to the use of powdered ginger against their afflictions.
Amongst the arthritis patients more than three-quarters experienced, to varying degrees, relief in pain and swelling. All the patients with muscular discomfort experienced relief in pain.
None of the patients reported adverse effects during the period of ginger consumption which ranged from 3 months to 2.5 years.
Further analysis of the results, researchers found that ginger exerts similar effects to that of conventional medicine as an important mediator of inflammation.
Dr. Srivastava KC, the lead scientist wrote in the final report, "At least one of the mechanisms by which ginger shows its ameliorative effects could be related to the inhibition of prostaglandin and leukotriene biosynthesis., i.e. it works as a dual inhibitor of eicosanoid biosynthesis".
Additionally, compared to conventional medicine such as non-steroidal anti-inflammatory drugs and corticosteroids which treat rheumatic diseases by inhibiting the cyclooxygenase associated with the symptoms of inflammation and pain, ginger demonstrated similar effects and improve quality of life in patients with rheumatic diseases, without inducing any side effects during the course of the experiment.
These results clearly suggested that ginger may be considered a functional food for the prevention and treatment of rheumatism with no adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders by Srivastava KC1, Mustafa T. (PubMed)
(2) Ginger (Zingiber officinale) and rheumatic disorders by Srivastava KC1, Mustafa T. (PubMed)
(3) Obesity as a Risk and Severity Factor in Rheumatic Diseases (Autoimmune Chronic Inflammatory Diseases) by Elisa Gremese,1 Barbara Tolusso,1 Maria Rita Gigante,1 and Gianfranco Ferraccioli. (PMC)
Rheumatism is an autoimmune and inflammatory disease marked by inflammation and pain in the joints, muscles, or fibrous tissue, especially rheumatoid arthritis.
In other words, rheumatic diseases are medical and chronic conditions characterized by inflammation that affects your joints tendons, ligaments, bones, and muscles, including a group of diseases associated with arthritis.
Depending on the types of rheumatic diseases, conventional treatment may include medication for reducing the symptoms, physiotherapy, and stress management. The aim of the treatment is to alleviate pain and improve the quality of life. Sadly, none of the drugs has been found safe; all are known to produce mild to serious side effects.
The most common symptoms of rheumatic diseases are joint pain, and reduced motion in a joint, particularly, joint inflammation that induces swelling, and redness, on the affected area.
If you experience some of the above symptoms, you may have rheumatic diseases, please make sure you check with your doctor to rule out the possibility.
There is no single cause of rheumatic diseases. Researchers believe groups of factors such as genes and environmental influences may be associated with the onset of the diseases, including the increase in age, gender, family history, exposure to environmental toxic substances, and smoking.
However, the most common risk factor for rheumatic diseases in the Western world is obesity. Dr. the lead scientist, in the examination of the risk of obesity for the onset of rheumatic diseases, said, "The growing body of evidence recognizing the adipose tissue (AT) as an active endocrine organ secreting bioactive mediators involved in metabolic and inflammatory disorders, together with the global epidemic of overweight and obesity, rise obesity as a hot topic of current research".
" The chronic state of low-grade inflammation present in the obese condition and the multiple pleiotropic effects of adipokines on the immune system has been implicated in the pathogenesis of several inflammatory conditions including rheumatic autoimmune and inflammatory diseases".
Ginger (Zingiber officinale) or ginger root, the second superfood used for thousands of years by mankind, is the genus Zingiber, belonging to the family Zingiberaceae, native to Tamil.
The root has been used in traditional and Chinese medicine to treat dyspepsia, gastroparesis, constipation, edema, difficult urination, colic, etc.
With an aim to find a natural ingredient or whole food for the prevention and treatment of rheumatic autoimmune and inflammatory diseases with no side effects, scientists at Odense University examine the traditional use of ginger against rheumatism.
The study included 56 patients (28 with rheumatoid arthritis, 18 with osteoarthritis, and 10 with muscular discomfort) randomly assigned to the use of powdered ginger against their afflictions.
Amongst the arthritis patients more than three-quarters experienced, to varying degrees, relief in pain and swelling. All the patients with muscular discomfort experienced relief in pain.
None of the patients reported adverse effects during the period of ginger consumption which ranged from 3 months to 2.5 years.
Further analysis of the results, researchers found that ginger exerts similar effects to that of conventional medicine as an important mediator of inflammation.
Dr. Srivastava KC, the lead scientist wrote in the final report, "At least one of the mechanisms by which ginger shows its ameliorative effects could be related to the inhibition of prostaglandin and leukotriene biosynthesis., i.e. it works as a dual inhibitor of eicosanoid biosynthesis".
Additionally, compared to conventional medicine such as non-steroidal anti-inflammatory drugs and corticosteroids which treat rheumatic diseases by inhibiting the cyclooxygenase associated with the symptoms of inflammation and pain, ginger demonstrated similar effects and improve quality of life in patients with rheumatic diseases, without inducing any side effects during the course of the experiment.
These results clearly suggested that ginger may be considered a functional food for the prevention and treatment of rheumatism with no adverse effects.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's News, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Ginger (Zingiber officinale) in rheumatism and musculoskeletal disorders by Srivastava KC1, Mustafa T. (PubMed)
(2) Ginger (Zingiber officinale) and rheumatic disorders by Srivastava KC1, Mustafa T. (PubMed)
(3) Obesity as a Risk and Severity Factor in Rheumatic Diseases (Autoimmune Chronic Inflammatory Diseases) by Elisa Gremese,1 Barbara Tolusso,1 Maria Rita Gigante,1 and Gianfranco Ferraccioli. (PMC)
#Piperine Plus #Curcumin Protect the Neurons Against #CognitiveImpairment Associated with Oxidative Damage in Vivos, Researchers Find
Kyle J. Norton
Phytochemical piperine may be the next therapeutic ingredient for the prevention and treatment of cognitive impairment, some scientists suggested.
Cognition is the process of the brain including the attention of working memory, producing and comprehending language, learning, reasoning, problem-solving, and decision-making.
Cognitive impairment is the condition, affecting a person's thinking, communication, understanding, or memory. Cognitive impairment can be acute or chronic.
Acute cognitive impairment is a short-term health problem caused by delirium, an acutely disturbed state of mind due to drugs (toxicity and withdrawal), electrolyte disturbance, lack of drugs, liver disease, infection, reduced sensory input, intracranial urinary retention/fecal impaction or m Myocardial/metabolic/pulmonary.
Chronic cognitive impairment is a permanent medical condition associated with problems of language, ideomotor and constructive praxis, visual gnosis, spatial attention, learning abilities, and executive functions.
There is no single cause of cognitive impairment. Some researchers suggested that depending on the locations of the brain that were affected, patients may be at risk of Alzheimer's disease if the brain change is caused by the abnormal clumps of beta-amyloid protein (plaques) and microscopic protein clumps of tau, Lewy bodies if the change is a result of microscopic clumps of another protein associated with Parkinson's disease, dementia with Lewy bodies and some cases of Alzheimer's disease.
Small strokes or reduced blood flow through brain blood vessels can also cause chronic cognitive impairment.
According to the observation of the patient's MRI, the patient's brain with cognitive impairment also showed shrinkage of the hippocampus, a brain region important for memory, enlargement of the brain's fluid-filled spaces (ventricles), and reduced use of glucose, the sugar that's the primary source of energy for cells.
Risk factors associated with the onset of chronic cognitive impairment include the increase in age, genetic preposition, certain medical conditions, such as diabetes, high blood cholesterol, and pressure, being obese, and lack of exercise.
According to a joint study led by the Health Innovations Research Institute, obesity is also one of the major risk factors for cognitive impairment in the Western world.
Dr. Jason C. D. Nguyen, the lead author in the team wrote in the final report, "The incidence of obesity in middle age is increasing markedly, and in parallel, the prevalence of metabolic disorders including cardiovascular disease and type II diabetes is also rising. Numerous studies have demonstrated that both obesity and metabolic disorders are associated with poorer cognitive performance, cognitive decline, and dementia".
Piperine is a phytochemical alkaloid in the class of organosulfur compounds, found abundantly in white and black pepper, long pepper, etc.
On finding natural ingredients for the prevention of cognitive impairment caused by oxidative damage in the brain neurons, researchers at the University Institute of Pharmaceutical Sciences examine the cognition protective effects of piperine co-administration with curcumin.
Cognitive impairment and oxidative stress mice induced by chronic stress (CS) were selected for the study.
Before administration of piperine + curcumin, chronic stress mice showed significantly impaired memory performance (delayed latency time to reach the platform) and decreased locomotor activity along with sucrose consumption.
Furthermore, without infection of piperine + curcumin, the tested mice also demonstrated significant impairment in oxidative parameters observed by the elevated malondialdehyde, and nitrite concentration and decreased reduced glutathione, and catalase levels) and reduced hydrolytic metabolism in transmitting information between neurons.
Application of piperine + curcumin restored all parameters induced by chronic stress, including the normalized cognitive function, and improved the antioxidant status against overexpression of free radicals.
Most importantly, co-administration of piperine (20mg/kg; p.o.) with curcumin (100 and 200mg/kg, p.o.) significantly elevated the cognitive protective effect compared to individual use.
Dr. Rinwa P, the lead scientist said in the final report, "Piperine enhanced the bioavailability of curcumin and potentiated its protective effects against CUS-induced cognitive impairment and associated oxidative damage in mice".
In order to reconfirm the co-administration of piperine with curcumin the neuroprotective effects, researchers elucidate the neuroprotective mechanism of curcumin and its co-administration with piperine against olfactory bulbectomy-induced depression in rats.
Before injecting piperine + curcumin, the tested rat showed depression-like symptoms as evidenced by increased immobility time in FST, hyperactivity in open field arena, and anhedonic-like response in SPT along with alterations in mitochondrial enzyme complexes, increased serum corticosterone levels and oxidative damage similar to those of the previous study.
The overexpression of pro-inflammatory cytokines, proteins associated with neuron apoptosis, and oxidative stress in tested rats caused by olfactory bulbectomy were also inhibited by the co-administration of piperine with curcumin.
The in-depth analysis suggested that the combination of piperine plus curcumin treatment significantly and dose-dependently restored all behavioral, biochemical, mitochondrial, molecular, and histopathological alterations associated with OBX-induced depression.
Dr. Rinwa P said, "Curcumin along with piperine exhibits neuroprotection against olfactory bulbectomy-induced depression possibly by modulating oxidative-nitrosative stress-induced neuroinflammation and apoptosis".
Taken together, the discovery strongly supports the use of piperine and curcumin for the prevention and treatment of cognitive impairment, pending the reconfirmation of larger sample size and multicenter possibility.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice by Rinwa P, Kumar A.(PubMed)
(2) Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in a rat model of olfactory bulbectomy induced depression by Rinwa P, Kumar A, Garg S.(PubMed)
(3) Protective effect of curcumin and its combination with piperine(bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence by Bishnoi M, Chopra K, Rongzhu L, Kulkarni SK. (PubMed)
(4) Obesity and cognitive decline: role of inflammation and vascular changes by Jason C. D. Nguyen,1 A. Simon Killcross,2 and Trisha A. Jenkins. (PMC)
Phytochemical piperine may be the next therapeutic ingredient for the prevention and treatment of cognitive impairment, some scientists suggested.
Cognition is the process of the brain including the attention of working memory, producing and comprehending language, learning, reasoning, problem-solving, and decision-making.
Cognitive impairment is the condition, affecting a person's thinking, communication, understanding, or memory. Cognitive impairment can be acute or chronic.
Acute cognitive impairment is a short-term health problem caused by delirium, an acutely disturbed state of mind due to drugs (toxicity and withdrawal), electrolyte disturbance, lack of drugs, liver disease, infection, reduced sensory input, intracranial urinary retention/fecal impaction or m Myocardial/metabolic/pulmonary.
Chronic cognitive impairment is a permanent medical condition associated with problems of language, ideomotor and constructive praxis, visual gnosis, spatial attention, learning abilities, and executive functions.
There is no single cause of cognitive impairment. Some researchers suggested that depending on the locations of the brain that were affected, patients may be at risk of Alzheimer's disease if the brain change is caused by the abnormal clumps of beta-amyloid protein (plaques) and microscopic protein clumps of tau, Lewy bodies if the change is a result of microscopic clumps of another protein associated with Parkinson's disease, dementia with Lewy bodies and some cases of Alzheimer's disease.
Small strokes or reduced blood flow through brain blood vessels can also cause chronic cognitive impairment.
According to the observation of the patient's MRI, the patient's brain with cognitive impairment also showed shrinkage of the hippocampus, a brain region important for memory, enlargement of the brain's fluid-filled spaces (ventricles), and reduced use of glucose, the sugar that's the primary source of energy for cells.
Risk factors associated with the onset of chronic cognitive impairment include the increase in age, genetic preposition, certain medical conditions, such as diabetes, high blood cholesterol, and pressure, being obese, and lack of exercise.
According to a joint study led by the Health Innovations Research Institute, obesity is also one of the major risk factors for cognitive impairment in the Western world.
Dr. Jason C. D. Nguyen, the lead author in the team wrote in the final report, "The incidence of obesity in middle age is increasing markedly, and in parallel, the prevalence of metabolic disorders including cardiovascular disease and type II diabetes is also rising. Numerous studies have demonstrated that both obesity and metabolic disorders are associated with poorer cognitive performance, cognitive decline, and dementia".
Piperine is a phytochemical alkaloid in the class of organosulfur compounds, found abundantly in white and black pepper, long pepper, etc.
On finding natural ingredients for the prevention of cognitive impairment caused by oxidative damage in the brain neurons, researchers at the University Institute of Pharmaceutical Sciences examine the cognition protective effects of piperine co-administration with curcumin.
Cognitive impairment and oxidative stress mice induced by chronic stress (CS) were selected for the study.
Before administration of piperine + curcumin, chronic stress mice showed significantly impaired memory performance (delayed latency time to reach the platform) and decreased locomotor activity along with sucrose consumption.
Furthermore, without infection of piperine + curcumin, the tested mice also demonstrated significant impairment in oxidative parameters observed by the elevated malondialdehyde, and nitrite concentration and decreased reduced glutathione, and catalase levels) and reduced hydrolytic metabolism in transmitting information between neurons.
Application of piperine + curcumin restored all parameters induced by chronic stress, including the normalized cognitive function, and improved the antioxidant status against overexpression of free radicals.
Most importantly, co-administration of piperine (20mg/kg; p.o.) with curcumin (100 and 200mg/kg, p.o.) significantly elevated the cognitive protective effect compared to individual use.
Dr. Rinwa P, the lead scientist said in the final report, "Piperine enhanced the bioavailability of curcumin and potentiated its protective effects against CUS-induced cognitive impairment and associated oxidative damage in mice".
In order to reconfirm the co-administration of piperine with curcumin the neuroprotective effects, researchers elucidate the neuroprotective mechanism of curcumin and its co-administration with piperine against olfactory bulbectomy-induced depression in rats.
Before injecting piperine + curcumin, the tested rat showed depression-like symptoms as evidenced by increased immobility time in FST, hyperactivity in open field arena, and anhedonic-like response in SPT along with alterations in mitochondrial enzyme complexes, increased serum corticosterone levels and oxidative damage similar to those of the previous study.
The overexpression of pro-inflammatory cytokines, proteins associated with neuron apoptosis, and oxidative stress in tested rats caused by olfactory bulbectomy were also inhibited by the co-administration of piperine with curcumin.
The in-depth analysis suggested that the combination of piperine plus curcumin treatment significantly and dose-dependently restored all behavioral, biochemical, mitochondrial, molecular, and histopathological alterations associated with OBX-induced depression.
Dr. Rinwa P said, "Curcumin along with piperine exhibits neuroprotection against olfactory bulbectomy-induced depression possibly by modulating oxidative-nitrosative stress-induced neuroinflammation and apoptosis".
Taken together, the discovery strongly supports the use of piperine and curcumin for the prevention and treatment of cognitive impairment, pending the reconfirmation of larger sample size and multicenter possibility.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) piperine potentiates the protective effects of curcumin against chronic unpredictable stress-induced cognitive impairment and oxidative damage in mice by Rinwa P, Kumar A.(PubMed)
(2) Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in a rat model of olfactory bulbectomy induced depression by Rinwa P, Kumar A, Garg S.(PubMed)
(3) Protective effect of curcumin and its combination with piperine(bioavailability enhancer) against haloperidol-associated neurotoxicity: cellular and neurochemical evidence by Bishnoi M, Chopra K, Rongzhu L, Kulkarni SK. (PubMed)
(4) Obesity and cognitive decline: role of inflammation and vascular changes by Jason C. D. Nguyen,1 A. Simon Killcross,2 and Trisha A. Jenkins. (PMC)
Celery's Ethanol/water (1:1) Extract Shows a Significant Inhibitory Activity on Nitrite (NO) Production and iNOS Expression Associated with The Onset of #InflammatoryDiseases
Kyle J. Norton
Celery may have a profound and positive effect on the prevention and treatment of chronic inflammatory diseases, some scientists found.
Inflammation is a natural reaction to a systematic immune response that protects our body against stimuli or invasive pathogens.
Acute inflammation is a result of the immune white blood cell response to tissue damage or injury by stimulating the production of proinflammatory cytokines with an aim to kill off the microorganism which tries to enter the body through the wound.
Chronic inflammation is a condition of low-grade inflammation adopted by the immunity caused by the immune inability to kill off all invaders in the acute phase of infection.
Some researchers then examine the immune evolution over thousands of years suggested that the immune system has evolved to destroy foreign pathogens after entering in a specific time within 3 -8 weeks, otherwise, it will adapt to the change.
Chronic inflammation also is an autoimmune disease caused by the immune system mistakenly attacks the bodily tissue.
Epidemiological studies suggested that aging that causes low production of sex hormones, being obese and obese, and smoking are associated with the early onset of chronic inflammatory diseases.
Some researchers suggested that out of several risk factors, a poor diet in the long term is one of the major causes of chronic inflammatory diseases.
Dr. Anne M. Minihane, the lead author in the examine the risk of low-grade inflammation in diet composition and health said, "The ability of diet to positively modulate inflammation and provide the much-needed evidence to develop research portfolios that will inform new product development and associated health claims".
The statement clearly suggested that people who follow a healthy diet pattern with high fruits and vegetables and whole grains and low saturated and trans fat, red meat, and processed food are less likely to be infected by chronic inflammatory diseases.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. It is cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
Too find a natural whole food for the prevention and treatment of chronic inflammatory disease, researchers looked into the group of flavones that have reported anti-inflammatory activities and examined the ability of flavone-rich foods to reduce inflammation.
Celery extracts, with anti-inflammatory activities and rich in flavone aglycones, were selected for the study.
Celery diets with different glycoside or aglycone contents were formulated and absorption was evaluated in mice fed with 5 or 10% celery diets.
Intake of deglycosylation was found to increase the absorption of dietary flavones in vivo and modulates inflammation by reducing TNF-α, the pro-inflammatory cytokines, and NF-κB, which regulates multiple aspects of innate and adaptive immune functions and serves as a pivotal mediator of inflammatory responses.
The results suggested that celery extract rich in flavones may have the potential for the treatment and prevention of inflammatory diseases.
Additional differentiation of the anti-inflammatory and immunomodulatory activity in-vitro and in-vivo of the compound flavonoids found abundantly in celery, researchers launched an evaluation to examine the effects of the ethanol/water (1:1) extract of the leaves of Apium graveolens var. dulce (celery) on iNOS expression and NO production in a tested macrophage cell line stimulated for 24 h with Escherichia coli lipopolysaccharide (LPS).
Where the inducible nitric oxide synthase (iNOS) is one of the direct consequences of the inflammatory process and overproduction of NO is considered a pro-inflammatory mediator that induces inflammation.
In vitro, treatment of the extract and apiin showed significant inhibitory activity on nitrite (NO) production and iNOS expression observed by the tested cell line assay.
Interestingly, the extract exerted anti-inflammatory activity in-vivo (ID50 730 microg cm(-2)), with a potency seven times lower than those of indomethacin (ID50 93 microg cm(-2)), the non-steroidal anti-inflammatory drug used as references.
The finding clearly suggested the inhibitory activity of the extract and apiin in-vitro on iNOS expression and nitrite production.
Taken together, celery may be considered a functional food for the prevention and treatment of acute and chronic inflammatory diseases without inducing any side effects, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Flavone deglycosylation increases their anti-inflammatory activity and absorption by Hostetler G1, Riedl K, Cardenas H, Diosa-Toro M, Arango D, Schwartz S, Doseff AI. (PubMed)
(2) An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties by Mencherini T1, Cau A, Bianco G, Della Loggia R, Aquino RP, Autore G.(PubMed).
(3) Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some herbal/animal products by Whitehouse MW1, Butters DE. (PubMed)
(4) Low-grade inflammation, diet composition and health: current research evidence and its translation by Anne M. Minihane 1 ,* Sophie Vinoy, 2 Wendy R. Russell, 3 Athanasia Baka, 4 Helen M. Roche,5 Kieran M. Tuohy, 6 Jessica L. Teeling, 7 Ellen E. Blaak, 8 Michael Fenech, 9 David Vauzour, 1Harry J. McArdle, 3 Bas H. A. Kremer, 10 Luc Sterkman, 11 Katerina Vafeiadou, 12Massimo Massi Benedetti, 13 Christine M. Williams, 14 and Philip C. Calder. (PMC)
Celery may have a profound and positive effect on the prevention and treatment of chronic inflammatory diseases, some scientists found.
Inflammation is a natural reaction to a systematic immune response that protects our body against stimuli or invasive pathogens.
Acute inflammation is a result of the immune white blood cell response to tissue damage or injury by stimulating the production of proinflammatory cytokines with an aim to kill off the microorganism which tries to enter the body through the wound.
Chronic inflammation is a condition of low-grade inflammation adopted by the immunity caused by the immune inability to kill off all invaders in the acute phase of infection.
Some researchers then examine the immune evolution over thousands of years suggested that the immune system has evolved to destroy foreign pathogens after entering in a specific time within 3 -8 weeks, otherwise, it will adapt to the change.
Chronic inflammation also is an autoimmune disease caused by the immune system mistakenly attacks the bodily tissue.
Epidemiological studies suggested that aging that causes low production of sex hormones, being obese and obese, and smoking are associated with the early onset of chronic inflammatory diseases.
Some researchers suggested that out of several risk factors, a poor diet in the long term is one of the major causes of chronic inflammatory diseases.
Dr. Anne M. Minihane, the lead author in the examine the risk of low-grade inflammation in diet composition and health said, "The ability of diet to positively modulate inflammation and provide the much-needed evidence to develop research portfolios that will inform new product development and associated health claims".
The statement clearly suggested that people who follow a healthy diet pattern with high fruits and vegetables and whole grains and low saturated and trans fat, red meat, and processed food are less likely to be infected by chronic inflammatory diseases.
Celery is a species of Apium graveolens, belonging to the family Apiaceae. It is cultivated all around the globe as a vegetable. Celery can grow to 1/2 m tall with stalks (leaf on the top) arranged in a conical shape joined at a common base.
Too find a natural whole food for the prevention and treatment of chronic inflammatory disease, researchers looked into the group of flavones that have reported anti-inflammatory activities and examined the ability of flavone-rich foods to reduce inflammation.
Celery extracts, with anti-inflammatory activities and rich in flavone aglycones, were selected for the study.
Celery diets with different glycoside or aglycone contents were formulated and absorption was evaluated in mice fed with 5 or 10% celery diets.
Intake of deglycosylation was found to increase the absorption of dietary flavones in vivo and modulates inflammation by reducing TNF-α, the pro-inflammatory cytokines, and NF-κB, which regulates multiple aspects of innate and adaptive immune functions and serves as a pivotal mediator of inflammatory responses.
The results suggested that celery extract rich in flavones may have the potential for the treatment and prevention of inflammatory diseases.
Additional differentiation of the anti-inflammatory and immunomodulatory activity in-vitro and in-vivo of the compound flavonoids found abundantly in celery, researchers launched an evaluation to examine the effects of the ethanol/water (1:1) extract of the leaves of Apium graveolens var. dulce (celery) on iNOS expression and NO production in a tested macrophage cell line stimulated for 24 h with Escherichia coli lipopolysaccharide (LPS).
Where the inducible nitric oxide synthase (iNOS) is one of the direct consequences of the inflammatory process and overproduction of NO is considered a pro-inflammatory mediator that induces inflammation.
In vitro, treatment of the extract and apiin showed significant inhibitory activity on nitrite (NO) production and iNOS expression observed by the tested cell line assay.
Interestingly, the extract exerted anti-inflammatory activity in-vivo (ID50 730 microg cm(-2)), with a potency seven times lower than those of indomethacin (ID50 93 microg cm(-2)), the non-steroidal anti-inflammatory drug used as references.
The finding clearly suggested the inhibitory activity of the extract and apiin in-vitro on iNOS expression and nitrite production.
Taken together, celery may be considered a functional food for the prevention and treatment of acute and chronic inflammatory diseases without inducing any side effects, pending the validation of a larger sample size and multicenter human study.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Flavone deglycosylation increases their anti-inflammatory activity and absorption by Hostetler G1, Riedl K, Cardenas H, Diosa-Toro M, Arango D, Schwartz S, Doseff AI. (PubMed)
(2) An extract of Apium graveolens var. dulce leaves: structure of the major constituent, apiin, and its anti-inflammatory properties by Mencherini T1, Cau A, Bianco G, Della Loggia R, Aquino RP, Autore G.(PubMed).
(3) Combination anti-inflammatory therapy: synergism in rats of NSAIDs/corticosteroids with some herbal/animal products by Whitehouse MW1, Butters DE. (PubMed)
(4) Low-grade inflammation, diet composition and health: current research evidence and its translation by Anne M. Minihane 1 ,* Sophie Vinoy, 2 Wendy R. Russell, 3 Athanasia Baka, 4 Helen M. Roche,5 Kieran M. Tuohy, 6 Jessica L. Teeling, 7 Ellen E. Blaak, 8 Michael Fenech, 9 David Vauzour, 1Harry J. McArdle, 3 Bas H. A. Kremer, 10 Luc Sterkman, 11 Katerina Vafeiadou, 12Massimo Massi Benedetti, 13 Christine M. Williams, 14 and Philip C. Calder. (PMC)
#Avocado Seed and Fruit Oil Extracts in the Promotion of #Skinhealth Show A Significant Increase in Soluble Collagen Content in the Skin, Researchers Say
Kyle J. Norton
Skin, a large organ of the body protects our tissue and organs against the invasion of pathogens and fluid loss.
There are many causes of skin damage. Sun exposure is the most common cause of skin damage. Other causes of skin damage include smoking cigarettes, drinking too much alcohol, extreme temperatures, and exposure to toxic chemicals and pollutants in the air outside.
Some researchers suggested that free radicals bombard our bodies daily are also associated with skin damage in the modern world.
Free radicals are unstable molecules with the unpaired electron on the outer ring. In order for them to become balanced, free radical either donates or intercept an electron from another stable molecule, leading to a chain reaction that can not be stopped until the outer ring election is paired or inhibited by an antioxidant.
In fact, free radical formation occurs continuously in the cells as a consequence of both enzymatic and nonenzymatic reactions, they can be generated by our bodies such as the process of metabolism and exogenous sources such as pollution, alcohol, and tobacco smoke.
Free radicals can affect our skin in different ways, including the alternation of the DNA, damage of lipid membranes, and collagen structures, and inducing photoaging and cancer.
Dr. Borut Poljšak, in the study "Free Radicals and Extrinsic Skin Aging," wrote, "Extrinsic skin damage develops due to several factors: ionizing radiation, severe physical and psychological stress, alcohol intake, poor nutrition, overeating, environmental pollution, and exposure to UV radiation (UVR)". and
"The only protection of our skin is in its endogenous protection (melanin and enzymatic antioxidants) and antioxidants we consume from the food (vitamin A, C, E, etc.)".
These results suggested that although free radicals can induce the early onset of skin damage and aging, providing our body with enough antioxidants from food sources is the best way to counter the process.
Avocado is a commercially valuable fruit cultivated in tropical climates throughout the world. It is a green-skinned, pear-shaped fruit that ripens after harvesting and is native to the Caribbean, Mexico, South America, and Central America, belonging to the flowering plant family Lauraceae.
In finding a natural ingredient or essential oil which has a potential effect on skin health without inducing any side effects, researchers explored the effects of various avocado oils on collagen metabolism.
In skin rats fed diets containing 10% (w/w) of the tested oils, researchers found the akin protective effects were totally dependent on the types of avocado oil.
Rats fed the unrefined avocado oil extracted with hexane from the intact fruit, including unsaponifiable or avocado seed oil, showed a significant increase in soluble collagen content in the skin, though total collagen content was not affected.
The increased soluble collagen content was attributed to the inhibition of lysyl oxidase activity whose increment is associated with the oxidative stress induced by chronic exposure to skin harmful substances.
The active factor which protects skin health was found to be present in the unrefined avocado oil and probably originated from the avocado seed, observed by the collagen metabolism which is affected only by fractions containing lipids fraction from the seed.
In order to illustrate the effects of avocado oil on skin health, researchers evaluated the wound-healing activity of a semisolid formulation of avocado oil, SSFAO 50%, or avocado oil in natural, incisional, and excisional cutaneous wound models in Wistar rats.
On the 14 days of application on the wound, 50% SSFAO or avocado oil demonstrate a significant increase in percentage wound contraction and reepithelialization, compared to the petroleum jelly control.
The treatment group also displayed an increase in anti-inflammatory activity, density of collagen, and tensile strength, compared to control groups.
This efficacy of the 50% SSFAO or avocado oil was attributed to the contents of the bioactive compounds, oleic fatty acid (47.20%), followed by palmitic (23.66%), linoleic (13.46%) docosadienoic (8.88%), palmitoleic (3.58%), linolenic (1.60%), eicosenoic (1.29%), and myristic acids (0.33%).
Dr. de Oliveira AP, the lead scientist wrote in the final report, "When used in natural or in pharmaceutical formulations for topical use, avocado oil can promote increased collagen synthesis and decreased numbers of inflammatory cells during the wound-healing process".
In skin exposure to ultraviolet (UV) radiation, unique lipid molecules, polyhydroxylated fatty alcohols (PFA), extracted from avocado, reduced significantly UV-induced cellular damage, through increasing cell viability, decreased the secretion of IL-6, a pro-inflammatory cytokine, and PGE(2) in mediated the inflammation process.
Taken altogether, avocado processed abundantly bioactive compounds may be considered a functional food for the promotion of skin health without inducing any side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The effect of various avocado oils on skin collagen metabolism by Werman MJ1, Mokady S, Nimni ME, Neeman I.(PubMed)
(2) Effect of semisolid formulation of persea americana mill (avocado) oil on wound healing in rats by de Oliveira AP1, Franco Ede S, Rodrigues Barreto R, Cordeiro DP, de Melo RG, de Aquino CM, E Silva AA, de Medeiros PL, da Silva TG, Góes AJ, Maia MB. (PubMed)
(3) Polyhydroxylated fatty alcohols derived from avocado suppress inflammatory response and provide non-sunscreen protection against UV-induced damage in skin cells by Rosenblat G1, Meretski S, Segal J, Tarshis M, Schroeder A, Zanin-Zhorov A, Lion G, Ingber A, Hochberg M.(PubMed)
(4) Free Radicals and Extrinsic Skin Aging by Borut Poljšak 1 and Raja Dahmane. (PMC)
Skin, a large organ of the body protects our tissue and organs against the invasion of pathogens and fluid loss.
There are many causes of skin damage. Sun exposure is the most common cause of skin damage. Other causes of skin damage include smoking cigarettes, drinking too much alcohol, extreme temperatures, and exposure to toxic chemicals and pollutants in the air outside.
Some researchers suggested that free radicals bombard our bodies daily are also associated with skin damage in the modern world.
Free radicals are unstable molecules with the unpaired electron on the outer ring. In order for them to become balanced, free radical either donates or intercept an electron from another stable molecule, leading to a chain reaction that can not be stopped until the outer ring election is paired or inhibited by an antioxidant.
In fact, free radical formation occurs continuously in the cells as a consequence of both enzymatic and nonenzymatic reactions, they can be generated by our bodies such as the process of metabolism and exogenous sources such as pollution, alcohol, and tobacco smoke.
Free radicals can affect our skin in different ways, including the alternation of the DNA, damage of lipid membranes, and collagen structures, and inducing photoaging and cancer.
Dr. Borut Poljšak, in the study "Free Radicals and Extrinsic Skin Aging," wrote, "Extrinsic skin damage develops due to several factors: ionizing radiation, severe physical and psychological stress, alcohol intake, poor nutrition, overeating, environmental pollution, and exposure to UV radiation (UVR)". and
"The only protection of our skin is in its endogenous protection (melanin and enzymatic antioxidants) and antioxidants we consume from the food (vitamin A, C, E, etc.)".
These results suggested that although free radicals can induce the early onset of skin damage and aging, providing our body with enough antioxidants from food sources is the best way to counter the process.
Avocado is a commercially valuable fruit cultivated in tropical climates throughout the world. It is a green-skinned, pear-shaped fruit that ripens after harvesting and is native to the Caribbean, Mexico, South America, and Central America, belonging to the flowering plant family Lauraceae.
In finding a natural ingredient or essential oil which has a potential effect on skin health without inducing any side effects, researchers explored the effects of various avocado oils on collagen metabolism.
In skin rats fed diets containing 10% (w/w) of the tested oils, researchers found the akin protective effects were totally dependent on the types of avocado oil.
Rats fed the unrefined avocado oil extracted with hexane from the intact fruit, including unsaponifiable or avocado seed oil, showed a significant increase in soluble collagen content in the skin, though total collagen content was not affected.
The increased soluble collagen content was attributed to the inhibition of lysyl oxidase activity whose increment is associated with the oxidative stress induced by chronic exposure to skin harmful substances.
The active factor which protects skin health was found to be present in the unrefined avocado oil and probably originated from the avocado seed, observed by the collagen metabolism which is affected only by fractions containing lipids fraction from the seed.
In order to illustrate the effects of avocado oil on skin health, researchers evaluated the wound-healing activity of a semisolid formulation of avocado oil, SSFAO 50%, or avocado oil in natural, incisional, and excisional cutaneous wound models in Wistar rats.
On the 14 days of application on the wound, 50% SSFAO or avocado oil demonstrate a significant increase in percentage wound contraction and reepithelialization, compared to the petroleum jelly control.
The treatment group also displayed an increase in anti-inflammatory activity, density of collagen, and tensile strength, compared to control groups.
This efficacy of the 50% SSFAO or avocado oil was attributed to the contents of the bioactive compounds, oleic fatty acid (47.20%), followed by palmitic (23.66%), linoleic (13.46%) docosadienoic (8.88%), palmitoleic (3.58%), linolenic (1.60%), eicosenoic (1.29%), and myristic acids (0.33%).
Dr. de Oliveira AP, the lead scientist wrote in the final report, "When used in natural or in pharmaceutical formulations for topical use, avocado oil can promote increased collagen synthesis and decreased numbers of inflammatory cells during the wound-healing process".
In skin exposure to ultraviolet (UV) radiation, unique lipid molecules, polyhydroxylated fatty alcohols (PFA), extracted from avocado, reduced significantly UV-induced cellular damage, through increasing cell viability, decreased the secretion of IL-6, a pro-inflammatory cytokine, and PGE(2) in mediated the inflammation process.
Taken altogether, avocado processed abundantly bioactive compounds may be considered a functional food for the promotion of skin health without inducing any side effects
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) The effect of various avocado oils on skin collagen metabolism by Werman MJ1, Mokady S, Nimni ME, Neeman I.(PubMed)
(2) Effect of semisolid formulation of persea americana mill (avocado) oil on wound healing in rats by de Oliveira AP1, Franco Ede S, Rodrigues Barreto R, Cordeiro DP, de Melo RG, de Aquino CM, E Silva AA, de Medeiros PL, da Silva TG, Góes AJ, Maia MB. (PubMed)
(3) Polyhydroxylated fatty alcohols derived from avocado suppress inflammatory response and provide non-sunscreen protection against UV-induced damage in skin cells by Rosenblat G1, Meretski S, Segal J, Tarshis M, Schroeder A, Zanin-Zhorov A, Lion G, Ingber A, Hochberg M.(PubMed)
(4) Free Radicals and Extrinsic Skin Aging by Borut Poljšak 1 and Raja Dahmane. (PMC)
#Yoga Alleviates #ChronicObstructivePulmonaryDisease #COPD Symptoms By Improving Inspiratory Capacity and Air Trapping, According to Studies
Kyle J. Norton
Yoga may be used as an integrated form of exercise in the treatment of chronic obstructive pulmonary disease, a randomized controlled study suggested.
Chronic obstructive pulmonary disease (COPD)) is the third leading cause of death in the United States, inducing symptoms of breathlessness and fatigue and making physical activity more challenging.
COPD is a chronic condition caused by lung inflammation that obstructs the airflow from the lungs.
The most common symptoms of COPD are breathing difficulty, cough, mucus (sputum) production,.... and wheezing.
According to the statistic, chronic obstructive pulmonary disease (COPD) affects about 32 million persons in the United States.
Conventional treatment of COPD focuses on the management to improve patients' functional status and quality of life by preserving remained lung function, according to Medscape
Yoga is the ancient practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement,.... and gesture.....
The technique is well-known to people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.
In a randomized trial with two study arms (yoga and control) a total of 81 coal miners enrolled, ranging from 36 to 60 years with stage II and III stable COPD, assigned either to conventional treatment or a combination of conventional care with yoga program for 12 weeks, after review the returned questionnaire, researchers found that
* Compared to other groups, the yoga group displays strong improvements in COPD on all scales.
*Also, Compared to the conventional treatment group, the yoga group expresses significantly positive effects in both physical and mental health status.
Dr. Ranjita R, the led researcher said, "Yoga seems to be a safe, feasible, and effective treatment for patients with COPD".
More profoundly, in the evaluated 43 patients with symptomatic, moderate-to-severe COPD assigned to the 12 weeks of pranayama plus education versus education alone taught by 2 yoga professionals, researchers indicated the following results
* Yoga group shows a strong performance in the 6-min walk distance (6MWD), compared to education the only group.
* Yoga also displays small improvements in inspiratory capacity and air trapping.
Researchers, after adjusting to other risk factors said, "Both groups had significant improvements in various measures of symptoms, but no overall differences in respiratory system impedance or markers of oxidative stress or systemic inflammation".
Truly, yoga posture and breathing practices improve blood circulation to the lung and muscle of the organ function, thus increasing the airflow to the lung in the absorption of volumes of oxygen for the body's needs.
With the additional supply of oxygen to the blood, patients with COPD not only can increase walking distance but also can perform other physical activities. Thus, enhancing the quality of life, including mental health.
In other words, yoga intervention significantly enhances inspiratory capacity and air trapping and improves the central nervous system in the regulation of certain hormones which have the functions in the stimulation of pro-inflammatory and anti-inflammatory expressions.
The efficacy of yoga mentioned above is also supported by the evaluated effects of yoga training on the quality of life (QOL) and the parameters of lung function in patients with COPD of 33 patients with COPD satisfied with the study criteria selected, after attending yoga exercises including breathing exercises, meditation, and yoga postures for 1 hour, thrice a week for 6 weeks by certified yoga therapists.
Compared to conventional treatment
* Yoga intervention showed an impressive improvement in vital capacity (95% CI 2.53-7.65), maximal inspiratory pressure, and maximal expiratory pressure, observed for the St. George Respiratory Questionnaire.
* The intervention also expressed short-term benefits in enhancing QOL and lung function
Taking it all together, yoga may be used as a secondary form of exercise combined with standard therapy for ameliorated symptoms and treatment for COPD patients.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A randomized controlled study on assessment of health status, depression, and anxiety in coal miners with the chronic obstructive pulmonary disease following yoga training by Ranjita R1, Badhai S1, Hankey A1, Nagendra HR1.(PubMed)
(2) Effect of Yoga Breathing (Pranayama) on Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease: A Randomized, Controlled Trial by Kaminsky DA1,2, Guntupalli KK3, Lippmann J2, Burns SM2, Brock MA3, Skelly J4, DeSarno M4, Pecott-Grimm H2, Mohsin A3, LaRock-McMahon C2, Warren P5, Whitney MC6, Hanania NA3.(PubMed)
(3) Yoga-based pulmonary rehabilitation for the management of dyspnea in coal miners with chronic obstructive pulmonary disease: A randomized controlled trial by Ranjita R1, Hankey A2, Nagendra HR2, Mohanty S2.(PubMed)
(4) Effect of yoga in chronic obstructive pulmonary disease by Fulambarker A1, Farooki B, Kheir F, Copur AS, Srinivasan L, Schultz S.(PubMed)
(5) Chronic Obstructive Pulmonary Disease (COPD) Treatment & Management
Updated: Jul 25, 2018, by Author: Zab Mosenifar, MD, FACP, FCCP; Chief Editor: John J Oppenheimer, MD more (Netscape)
Yoga may be used as an integrated form of exercise in the treatment of chronic obstructive pulmonary disease, a randomized controlled study suggested.
Chronic obstructive pulmonary disease (COPD)) is the third leading cause of death in the United States, inducing symptoms of breathlessness and fatigue and making physical activity more challenging.
COPD is a chronic condition caused by lung inflammation that obstructs the airflow from the lungs.
The most common symptoms of COPD are breathing difficulty, cough, mucus (sputum) production,.... and wheezing.
According to the statistic, chronic obstructive pulmonary disease (COPD) affects about 32 million persons in the United States.
Conventional treatment of COPD focuses on the management to improve patients' functional status and quality of life by preserving remained lung function, according to Medscape
Yoga is the ancient practice for harmonized external and internal body well-being, through breath control, meditation, bodily movement,.... and gesture.....
The technique is well-known to people in the Western world and some parts of Asia due to health benefits reported by various respectable institutes' research and supported by health advocates.
In a randomized trial with two study arms (yoga and control) a total of 81 coal miners enrolled, ranging from 36 to 60 years with stage II and III stable COPD, assigned either to conventional treatment or a combination of conventional care with yoga program for 12 weeks, after review the returned questionnaire, researchers found that
* Compared to other groups, the yoga group displays strong improvements in COPD on all scales.
*Also, Compared to the conventional treatment group, the yoga group expresses significantly positive effects in both physical and mental health status.
Dr. Ranjita R, the led researcher said, "Yoga seems to be a safe, feasible, and effective treatment for patients with COPD".
More profoundly, in the evaluated 43 patients with symptomatic, moderate-to-severe COPD assigned to the 12 weeks of pranayama plus education versus education alone taught by 2 yoga professionals, researchers indicated the following results
* Yoga group shows a strong performance in the 6-min walk distance (6MWD), compared to education the only group.
* Yoga also displays small improvements in inspiratory capacity and air trapping.
Researchers, after adjusting to other risk factors said, "Both groups had significant improvements in various measures of symptoms, but no overall differences in respiratory system impedance or markers of oxidative stress or systemic inflammation".
Truly, yoga posture and breathing practices improve blood circulation to the lung and muscle of the organ function, thus increasing the airflow to the lung in the absorption of volumes of oxygen for the body's needs.
With the additional supply of oxygen to the blood, patients with COPD not only can increase walking distance but also can perform other physical activities. Thus, enhancing the quality of life, including mental health.
In other words, yoga intervention significantly enhances inspiratory capacity and air trapping and improves the central nervous system in the regulation of certain hormones which have the functions in the stimulation of pro-inflammatory and anti-inflammatory expressions.
The efficacy of yoga mentioned above is also supported by the evaluated effects of yoga training on the quality of life (QOL) and the parameters of lung function in patients with COPD of 33 patients with COPD satisfied with the study criteria selected, after attending yoga exercises including breathing exercises, meditation, and yoga postures for 1 hour, thrice a week for 6 weeks by certified yoga therapists.
Compared to conventional treatment
* Yoga intervention showed an impressive improvement in vital capacity (95% CI 2.53-7.65), maximal inspiratory pressure, and maximal expiratory pressure, observed for the St. George Respiratory Questionnaire.
* The intervention also expressed short-term benefits in enhancing QOL and lung function
Taking it all together, yoga may be used as a secondary form of exercise combined with standard therapy for ameliorated symptoms and treatment for COPD patients.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) A randomized controlled study on assessment of health status, depression, and anxiety in coal miners with the chronic obstructive pulmonary disease following yoga training by Ranjita R1, Badhai S1, Hankey A1, Nagendra HR1.(PubMed)
(2) Effect of Yoga Breathing (Pranayama) on Exercise Tolerance in Patients with Chronic Obstructive Pulmonary Disease: A Randomized, Controlled Trial by Kaminsky DA1,2, Guntupalli KK3, Lippmann J2, Burns SM2, Brock MA3, Skelly J4, DeSarno M4, Pecott-Grimm H2, Mohsin A3, LaRock-McMahon C2, Warren P5, Whitney MC6, Hanania NA3.(PubMed)
(3) Yoga-based pulmonary rehabilitation for the management of dyspnea in coal miners with chronic obstructive pulmonary disease: A randomized controlled trial by Ranjita R1, Hankey A2, Nagendra HR2, Mohanty S2.(PubMed)
(4) Effect of yoga in chronic obstructive pulmonary disease by Fulambarker A1, Farooki B, Kheir F, Copur AS, Srinivasan L, Schultz S.(PubMed)
(5) Chronic Obstructive Pulmonary Disease (COPD) Treatment & Management
Updated: Jul 25, 2018, by Author: Zab Mosenifar, MD, FACP, FCCP; Chief Editor: John J Oppenheimer, MD more (Netscape)
#Blacktea Extract (BTE) Process an Anti Ulcer Activity by Restorating the Antioxidants of Serum GSH Level., Researchers Reveal
Kyle J. Norton
Black and green tea may have a therapeutic and positive effect on the prevention of dyspepsia, some scientists suggested.
Dyspepsia is a digestive condition of ingestion.
The exact causes of dyspepsia are unknown. However, researchers suggested that patients with the onset of a stomach ulcer or acid reflux disease are most susceptible to the condition.
Certain medication such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics (metronidazole, macrolides), and diseases such as irritable bowel syndrome is associated with an increased risk of dyspepsia.
Some researchers also suggested that unhealthy choices of lifestyle such as smoking, and excessive alcohol drinking also have a strong impact on the onset of the disease.
Dr. Umapati C. Baragi, the lead scientist in the study of diet and lifestyle in the etiopathogenesis of Urdhwaga Amlapitta (non-ulcer dyspepsia) said, "Dietary patterns, lifestyle choices, and physical activities play an important role in the etiopathogenesis of Urdhwaga Amlapitta, and it is important for patients to have access to diet and lifestyle modifications. Currently, research in this area is minimal"
Symptoms of dyspepsia include pain in the chest, stomach burning pain, bloating, heartburn, upset stomach,.... digestive discomforts.
If you experience the above symptoms, please check with your doctor to rule out the possibility.
Black tea is a beverage with more oxidization, compared to other teas such as oolong, green, and white teas.
In the investigation of aqueous extract (BTE) and thearubigins isolated from green tea effects in sildenafil-induced delay in gastric emptying (GE) and small intestinal transit (SIT) in a total of 160 mice, randomly assigned to 20 groups with 8 in each group, treated by different or combination of doses of BTE, thearubigins (TRs), sildenafil (SLD), metoclopramide, L-NAME (hydrochloride) and black tea extract researchers found that pretreatment of certain doses of green tea aqueous extract (BTE) and thearubigins significantly reverse motility-delaying effects caused by the injection of sildenafil.
Further differentiation also indicated that additional injection of black tea at 3% and 4.5% increases the function of thearubigins (50 and 60 mg/kg) dose-dependently in promoted dyspepsia in mice compared to the insignificant effect of the combination of BTE at 6% and thearubigins 70 mg/kg.
Moreover, the combination of metoclopramide, a medicine used mainly for the treatment of ingestion in people with delayed stomach emptying, BTE 4.5%, thearubigins 60 or nω -Nitro-l-arginine methyl ester hydrochloride (l-NAME) with sildenafil (5 mg/kg) reversed its motility-delaying effects,
This improvement of dyspepsia was partially blocked by the application of l-NAME through reducing function nitric oxide and improving gastrointestinal smooth muscle mobility by observation of the pretreatment of l-NAME followed by application of BTE alone or combination of thearubigins 60, BTE + sildenafil, and thearubigins + sildenafil.
Dr. Murad HA, the lead author, after taking into account confounders said, "BTE 4.5% or TRs 60 mg/kg solution could be considered a reliever therapy for the sildenafil-induced dyspepsia".
Additional investigations the role of hot water extract of black tea [Camellia sinensis (L) in normalizing the changes in the intestinal transit and gastric emptying induced by various ulcerogenic agents in experimental rats found that application of black tea extract significantly promotes the intestinal transit and gastric emptying caused by glutathione (GSH) depleting agents, diethyl maleate (DEM) in decreased mucosal content in aid of digestion, indoacetamide (IDA) in reduced stomach acid secretion, gastritis, and mucus thickness on gastric transfer and N-ethyl maleimide (NEM) with function of in significantly reduced the mucosal SH levels and the lesions.
Oral administration of black tea extract (BTE) at 20 ml/kg of a 10% solution once a day for 7 days also expressed a significantly increased intestinal transit and gastric emptying similar to those of conventional succimer (60 mg/kg, i.g.), the standard sulfhydryl containing an antiulcer agent
through the restoration of antioxidants of serum GSH level.
However, such increase of intestinal transit induced by BTE was reversed both by N-omega-nitro-L-arginine methyl ester (L-NAME) (25 mg/kg, i.p.) and N-omega-monomethyl-L-arginine (L-NMMA) (25 mg/kg, i.p.), in reduced levels of NO in the aided stomach in the production of gastric acid for digestive function.
Dr. Maity S, the lead author said, "Restoration of intestinal nitric oxide synthase (NOS) activity was found to be associated with BTE treatment" and "These results provide evidence that nitric oxide may play a role in BTE-mediated movement of intestinal motility changes and gastric emptying induced by DEM, IDA, and NEM".
Taken together, black tea with plenty of phytochemicals may be considered a functional food in reducing the risk and treatment of dyspepsia.
However, intake of tea supplements should be taken with exceptional care to prevent acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Black tea extract and its thearubigins relieve the sildenafil-induced delayed gut motility in mice: a possible role of nitric oxide by Murad HA1, Abdallah HM. (PubMed)
(2) Role of reduced glutathione and nitric oxide in the black tea extract-mediated protection against ulcerogen-induced changes in motility and gastric emptying in rats by Maity S1, Vedasiromoni JR, Chaudhuri L, Ganguly DK. (PubMed)
(3) Gastrointestinal transit during endotoxemia: the role of nitric oxide by Wirthlin DJ1, Cullen JJ, Spates ST, Conklin JL, Murray J, Caropreso DK, Ephgrave KS. (PubMed)
(4) Evaluation of diet and lifestyle in the etiopathogenesis of Urdhwaga Amlapitta (non-ulcer dyspepsia) by Umapati C. Baragi and Mahesh Kumar Vyas. (PubMed)
Black and green tea may have a therapeutic and positive effect on the prevention of dyspepsia, some scientists suggested.
Dyspepsia is a digestive condition of ingestion.
The exact causes of dyspepsia are unknown. However, researchers suggested that patients with the onset of a stomach ulcer or acid reflux disease are most susceptible to the condition.
Certain medication such as aspirin, nonsteroidal anti-inflammatory drugs (NSAIDs), antibiotics (metronidazole, macrolides), and diseases such as irritable bowel syndrome is associated with an increased risk of dyspepsia.
Some researchers also suggested that unhealthy choices of lifestyle such as smoking, and excessive alcohol drinking also have a strong impact on the onset of the disease.
Dr. Umapati C. Baragi, the lead scientist in the study of diet and lifestyle in the etiopathogenesis of Urdhwaga Amlapitta (non-ulcer dyspepsia) said, "Dietary patterns, lifestyle choices, and physical activities play an important role in the etiopathogenesis of Urdhwaga Amlapitta, and it is important for patients to have access to diet and lifestyle modifications. Currently, research in this area is minimal"
Symptoms of dyspepsia include pain in the chest, stomach burning pain, bloating, heartburn, upset stomach,.... digestive discomforts.
If you experience the above symptoms, please check with your doctor to rule out the possibility.
Black tea is a beverage with more oxidization, compared to other teas such as oolong, green, and white teas.
In the investigation of aqueous extract (BTE) and thearubigins isolated from green tea effects in sildenafil-induced delay in gastric emptying (GE) and small intestinal transit (SIT) in a total of 160 mice, randomly assigned to 20 groups with 8 in each group, treated by different or combination of doses of BTE, thearubigins (TRs), sildenafil (SLD), metoclopramide, L-NAME (hydrochloride) and black tea extract researchers found that pretreatment of certain doses of green tea aqueous extract (BTE) and thearubigins significantly reverse motility-delaying effects caused by the injection of sildenafil.
Further differentiation also indicated that additional injection of black tea at 3% and 4.5% increases the function of thearubigins (50 and 60 mg/kg) dose-dependently in promoted dyspepsia in mice compared to the insignificant effect of the combination of BTE at 6% and thearubigins 70 mg/kg.
Moreover, the combination of metoclopramide, a medicine used mainly for the treatment of ingestion in people with delayed stomach emptying, BTE 4.5%, thearubigins 60 or nω -Nitro-l-arginine methyl ester hydrochloride (l-NAME) with sildenafil (5 mg/kg) reversed its motility-delaying effects,
This improvement of dyspepsia was partially blocked by the application of l-NAME through reducing function nitric oxide and improving gastrointestinal smooth muscle mobility by observation of the pretreatment of l-NAME followed by application of BTE alone or combination of thearubigins 60, BTE + sildenafil, and thearubigins + sildenafil.
Dr. Murad HA, the lead author, after taking into account confounders said, "BTE 4.5% or TRs 60 mg/kg solution could be considered a reliever therapy for the sildenafil-induced dyspepsia".
Additional investigations the role of hot water extract of black tea [Camellia sinensis (L) in normalizing the changes in the intestinal transit and gastric emptying induced by various ulcerogenic agents in experimental rats found that application of black tea extract significantly promotes the intestinal transit and gastric emptying caused by glutathione (GSH) depleting agents, diethyl maleate (DEM) in decreased mucosal content in aid of digestion, indoacetamide (IDA) in reduced stomach acid secretion, gastritis, and mucus thickness on gastric transfer and N-ethyl maleimide (NEM) with function of in significantly reduced the mucosal SH levels and the lesions.
Oral administration of black tea extract (BTE) at 20 ml/kg of a 10% solution once a day for 7 days also expressed a significantly increased intestinal transit and gastric emptying similar to those of conventional succimer (60 mg/kg, i.g.), the standard sulfhydryl containing an antiulcer agent
through the restoration of antioxidants of serum GSH level.
However, such increase of intestinal transit induced by BTE was reversed both by N-omega-nitro-L-arginine methyl ester (L-NAME) (25 mg/kg, i.p.) and N-omega-monomethyl-L-arginine (L-NMMA) (25 mg/kg, i.p.), in reduced levels of NO in the aided stomach in the production of gastric acid for digestive function.
Dr. Maity S, the lead author said, "Restoration of intestinal nitric oxide synthase (NOS) activity was found to be associated with BTE treatment" and "These results provide evidence that nitric oxide may play a role in BTE-mediated movement of intestinal motility changes and gastric emptying induced by DEM, IDA, and NEM".
Taken together, black tea with plenty of phytochemicals may be considered a functional food in reducing the risk and treatment of dyspepsia.
However, intake of tea supplements should be taken with exceptional care to prevent acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Black tea extract and its thearubigins relieve the sildenafil-induced delayed gut motility in mice: a possible role of nitric oxide by Murad HA1, Abdallah HM. (PubMed)
(2) Role of reduced glutathione and nitric oxide in the black tea extract-mediated protection against ulcerogen-induced changes in motility and gastric emptying in rats by Maity S1, Vedasiromoni JR, Chaudhuri L, Ganguly DK. (PubMed)
(3) Gastrointestinal transit during endotoxemia: the role of nitric oxide by Wirthlin DJ1, Cullen JJ, Spates ST, Conklin JL, Murray J, Caropreso DK, Ephgrave KS. (PubMed)
(4) Evaluation of diet and lifestyle in the etiopathogenesis of Urdhwaga Amlapitta (non-ulcer dyspepsia) by Umapati C. Baragi and Mahesh Kumar Vyas. (PubMed)
#Beetroot Extract Combined with Chemo Drug #Doxorubicin (Adriamycin) Shows a Synergistic Cytotoxicityon Cancers, Scientists Reveal
Kyle J. Norton
Scientists may have found a vegetable that processes a potency in killing cancer cells before spreading, some studies suggested.
Cancer is a class of diseases in which a group of cells grow and multiply in disordered and uncontrollable ways in our body.
At the advanced stage, the invasive cancer cell can travel a distance away from the original site to infect other healthy tissues and organs via lymph or/and blood.
According to the statistic provided by the UK Cancers Research, in 2012, an estimated 14.1 million new cases of cancer occurred worldwide.
Sadly, more than 4 in ten cancers occurring worldwide are in countries at a low or medium level of Human Development Index (HDI).
The Human Development Index (HDI) is a statistical composite index of life expectancy, education, and per capita income indicators, according to the definition.
In 2018, over 1,7 million new cases of cancer are diagnosed in the US, and approximately over 600,000 patients will die from the disease.
The four most common types of cancer, occurring worldwide are lung, female breast, bowel, and prostate cancer.
Early diagnosis as always is the best way to improve survival rate. Depending on the type of cancer, most cancers have a 100% 5 years survival rate, if they are diagnosed at the stage of 0 and 1.
Beet is best known as the beetroot or garden beet and belongs to the Amaranth family. It is a perennial plant with leafy stems growing to 1–2 m tall.
In the study to reaffirm the effect of red beetroot (Beta vulgaris L.) extract (B), approved by the Food and Drug Administration and European Union as red food color E162, in reducing multi-organ tumor formations in various animal models when administered in drinking water, researchers at the Howard University launched an investigation to examine whether long-term daily exposure to low doses of B through diet would be safe and sufficient to produce cancer chemopreventive effect in humans.
Compared to the conventional chemo drugs doxorubicin (D) with different concentrations of range from 0.29-290 μg/ml in several human cancer cell lines, researchers found that
* Application of Red beetroot (Beta vulgaris L.) extract (B exerts a synergistic antiproliferative activity against pancreatic (PaCa), breast (MCF-7), and prostate (PC-3) tumor cells of human origin.
* Red beetroot (Beta vulgaris L.) extract (B) is considered safe for human use with no known toxicity.
* Used combined with D demonstrates an overall positive reduction of the concentration of D with the same cytotoxicity profile in the three human cancer cells. In other words, the synergistic cytotoxicity was best when the B:D ratio of 1:5 was used in PaCa cells at IC50, IC75, and IC90 dose levels and in MCF-7 cells at an IC90 dose level.
These results suggested that red beetroot extract used combined with doxorubicin may process a potency in treating human cancers.
Additionally, in further testing of the anti-cancer effect of the red beetroot extract with the anticancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3) and in the well-established estrogen receptor-positive human breast cancer cells (MCF-7), researchers showed that
* Both doxorubicin and the beetroot extract exhibit a dose-dependent cytotoxic effect in the two tested cancer cell lines.
* The cytotoxicity of the beetroot extract is significantly lower, compared to doxorubicin. Application of beetroot continues to decrease the growth rate of the PC-3 cells (3.7% in 3 days vs. 12.5% in 7 days) when tested at the concentration of 29 µg/ml in compared to doxorubicin completely inhibited the growth of the PC-3 cells in three days at the same concentration.
These results indicated lesser effects of the beetroot extract in inducing cytotoxicity, compared to doxorubicin (8.6% vs. 100%, respectively, at 29 µg/ml concentration of each, three-day test period).
Further analysis of the results, researchers found that the anticancer activity may be attributed to its bioactive compound betanin, the major betacyanin constituent.
The findings suggested that beetroot and its extract with abundant phytochemicals may be considered a functional food used alone or combined with chemo drugs for the treatment of cancers without inducing any side effects.
However, further data collection on large example size and multi-center studies performed with human consumption of the beer root extract during the course of the disease will be necessary to complete the picture of its anti-cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines by Kapadia GJ, Rao GS, Ramachandran C, Iida A, Suzuki N, Tokuda H.((PubMed)
(2) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancer cell lines by Kapadia GJ, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
Scientists may have found a vegetable that processes a potency in killing cancer cells before spreading, some studies suggested.
Cancer is a class of diseases in which a group of cells grow and multiply in disordered and uncontrollable ways in our body.
At the advanced stage, the invasive cancer cell can travel a distance away from the original site to infect other healthy tissues and organs via lymph or/and blood.
According to the statistic provided by the UK Cancers Research, in 2012, an estimated 14.1 million new cases of cancer occurred worldwide.
Sadly, more than 4 in ten cancers occurring worldwide are in countries at a low or medium level of Human Development Index (HDI).
The Human Development Index (HDI) is a statistical composite index of life expectancy, education, and per capita income indicators, according to the definition.
In 2018, over 1,7 million new cases of cancer are diagnosed in the US, and approximately over 600,000 patients will die from the disease.
The four most common types of cancer, occurring worldwide are lung, female breast, bowel, and prostate cancer.
Early diagnosis as always is the best way to improve survival rate. Depending on the type of cancer, most cancers have a 100% 5 years survival rate, if they are diagnosed at the stage of 0 and 1.
Beet is best known as the beetroot or garden beet and belongs to the Amaranth family. It is a perennial plant with leafy stems growing to 1–2 m tall.
In the study to reaffirm the effect of red beetroot (Beta vulgaris L.) extract (B), approved by the Food and Drug Administration and European Union as red food color E162, in reducing multi-organ tumor formations in various animal models when administered in drinking water, researchers at the Howard University launched an investigation to examine whether long-term daily exposure to low doses of B through diet would be safe and sufficient to produce cancer chemopreventive effect in humans.
Compared to the conventional chemo drugs doxorubicin (D) with different concentrations of range from 0.29-290 μg/ml in several human cancer cell lines, researchers found that
* Application of Red beetroot (Beta vulgaris L.) extract (B exerts a synergistic antiproliferative activity against pancreatic (PaCa), breast (MCF-7), and prostate (PC-3) tumor cells of human origin.
* Red beetroot (Beta vulgaris L.) extract (B) is considered safe for human use with no known toxicity.
* Used combined with D demonstrates an overall positive reduction of the concentration of D with the same cytotoxicity profile in the three human cancer cells. In other words, the synergistic cytotoxicity was best when the B:D ratio of 1:5 was used in PaCa cells at IC50, IC75, and IC90 dose levels and in MCF-7 cells at an IC90 dose level.
These results suggested that red beetroot extract used combined with doxorubicin may process a potency in treating human cancers.
Additionally, in further testing of the anti-cancer effect of the red beetroot extract with the anticancer drug, doxorubicin (Adriamycin) in the androgen-independent human prostate cancer cells (PC-3) and in the well-established estrogen receptor-positive human breast cancer cells (MCF-7), researchers showed that
* Both doxorubicin and the beetroot extract exhibit a dose-dependent cytotoxic effect in the two tested cancer cell lines.
* The cytotoxicity of the beetroot extract is significantly lower, compared to doxorubicin. Application of beetroot continues to decrease the growth rate of the PC-3 cells (3.7% in 3 days vs. 12.5% in 7 days) when tested at the concentration of 29 µg/ml in compared to doxorubicin completely inhibited the growth of the PC-3 cells in three days at the same concentration.
These results indicated lesser effects of the beetroot extract in inducing cytotoxicity, compared to doxorubicin (8.6% vs. 100%, respectively, at 29 µg/ml concentration of each, three-day test period).
Further analysis of the results, researchers found that the anticancer activity may be attributed to its bioactive compound betanin, the major betacyanin constituent.
The findings suggested that beetroot and its extract with abundant phytochemicals may be considered a functional food used alone or combined with chemo drugs for the treatment of cancers without inducing any side effects.
However, further data collection on large example size and multi-center studies performed with human consumption of the beer root extract during the course of the disease will be necessary to complete the picture of its anti-cancer possibilities.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blog, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
References
(1) Synergistic cytotoxicity of red beetroot (Beta vulgaris L.) extract with doxorubicin in human pancreatic, breast and prostate cancer cell lines by Kapadia GJ, Rao GS, Ramachandran C, Iida A, Suzuki N, Tokuda H.((PubMed)
(2) Cytotoxic effect of the red beetroot (Beta vulgaris L.) extract compared to doxorubicin (Adriamycin) in the human prostate (PC-3) and breast (MCF-7) cancer cell lines by Kapadia GJ, Azuine MA, Rao GS, Arai T, Iida A, Tokuda H. (PubMed)
#FennelGel 3% Shows a Significant Effect in the Reduction of the Thickness of Facial Hair in Micrometer, Researchers Say
Kyle J. Norton
Fennel may have a therapeutic effect in reducing the risk of unwanted hair growth in women, some scientists suggested.
Hirsutism is an unwanted hair growth pattern in women.
The exact causes of Hirsutism are unknown. However, researchers do know certain risk factors are associated with the early onset of the disease, including women who have a persistent hormone imbalance, and are obese.
Certain medical conditions such as polycystic ovary syndrome, infertility, long-term, irregular period, abnormal menstrual conditions and cysts present in the ovaries, and Cushing's syndrome are also considered the prevalent risk factors of Hirsutism.
Some women with the syndrome may experience symptoms of deepening voice, persistent acne on the facial skin, decreased breast size, increased muscle mass, and particularly, unwanted hair growth.
If you have some of the above symptoms, please check with your doctor to rule out the possibility.
In most cases, Hirsutism is treated by an androgen inhibitor such as spironolactone(Aldactone). Topical cream. Eflornithine (Vaniqa), a prescription cream is a primary treatment for women with excessive hair growth.
If you use the above medication, please make sure that know all the side effects.
Some researchers suggested due to the complex nature of the syndrome, management is usually a long and troublesome process.
Fennel (Foeniculum vulgare) is a plant species of the genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The herb or food has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and depressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
The double-blind study, using an ethanolic extract of Fennel, obtained by a Soxhlet apparatus to test the efficacy against the expression of idiopathic hirsutism of a total of 38 patients, includes women with idiopathic hirsutism, a normal ovulatory menstrual cycle and normal levels of serum androgens but exhibited male growth pattern were selected to participate.
All patients were assigned randomly to receive either topical cream containing 1%, 2% of Fennel extract, or placebo.
At the end of the experiment, researchers found that the application of fennel cream exerts a significant effect in reducing hair growth diameter compared to placebo.
Fennel cream with a 2% concentration displayed a strongly inhibited activity compared to cream with 1%.
Specifically, the mean values of hair diameter reduction were 7.8%, 18.3%, and -0.5% for patients receiving the creams containing 1%, 2%, and 0% (placebo) respectively, without inducing any untolerated adverse effects.
These results suggested that fennel ethanolic extract in reducing male hair growth patterns may be attributed to estrogenic properties in the activation of the molecular pathways involved in the estrogen-mediated induction of hair growth.
Dr. Ozra Akh, the lead author said, "Estrogens harness the making of dihydrotestosterone (DHT) in the papilla cells of the skin by controlling 5-alfa reductase enzyme or increasing the conversion of testosterone to weaker androgens and decreasing the testosterone available for conversion to DHT".
Truly, in the review of literature of randomized, double-blind, placebo-controlled clinical trial carried out from 2009 to 2011, in Sari, Iran with a total of 44 women with mild to moderate idiopathic hirsutism, researchers assigned participants either to the group of 22 treated with fennel gel 3% or the control group received placebo.
The mean age of both groups is not much different at 26.9±6.7 and 25.6±4.3 years in the case and control group, respectively, the researchers after taking into account co and confounders indicated that the application of fennel gel 3% demonstrates a significant effect in the reduction of the thickness of facial hair in micrometer by microscope compared to placebo, after 24 weeks of treatment.
The results of the score of both groups were compared to the baseline taken before the experiment
Although no severity of side effects was found during the period, 4 patients complained of itching (3 in the case group) and 4 patients complained of irritation and itching (3 in the case group).
In comparison to the results of 2 experiments used in the article, both 2% gel and 3% gel exerted a similar efficacy in treating idiopathic hirsutism in patients with mild, moderated, and excessive hair growth.
Truly, the property in reduced unwanted hair growth in the study was probably due to the presence of major bioactive phytochemical trans-anethole and di-anethole anti-androgenic effect.
Based on the evidence found, fennel may be considered a reliable and less expensive functional food for the treatment of idiopathic hirsutism.
However, due to the limited information provided by the small sample size, short period time of follow-up and the case severity does not include in both studies, Additional studies are necessary to reconfirm fennel anti Hirsutism viability.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antihirsutism activity of Fennel (fruits of Foeniculum vulgare) extract. A double-blind placebo-controlled study by Javidnia K1, Dastgheib L, Mohammadi Samani S, Nasiri A.(PubMed)
(2) The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo-controlled clinical trial by Ozra Akha, MD,1 Khadijeh Rabiei, MD,*,2 Zahra Kashi, MD,1 Adele Bahar, MD,1 Elham Zaeif-Khorasani, MD,1 Mehrnoush Kosaryan, MD,3 Majid Saeedi, Ph.D.,4 Mohammad Ali Ebrahimzadeh, Ph.D.,5 and Omid Emadian, MD(PubMed)
Fennel may have a therapeutic effect in reducing the risk of unwanted hair growth in women, some scientists suggested.
Hirsutism is an unwanted hair growth pattern in women.
The exact causes of Hirsutism are unknown. However, researchers do know certain risk factors are associated with the early onset of the disease, including women who have a persistent hormone imbalance, and are obese.
Certain medical conditions such as polycystic ovary syndrome, infertility, long-term, irregular period, abnormal menstrual conditions and cysts present in the ovaries, and Cushing's syndrome are also considered the prevalent risk factors of Hirsutism.
Some women with the syndrome may experience symptoms of deepening voice, persistent acne on the facial skin, decreased breast size, increased muscle mass, and particularly, unwanted hair growth.
If you have some of the above symptoms, please check with your doctor to rule out the possibility.
In most cases, Hirsutism is treated by an androgen inhibitor such as spironolactone(Aldactone). Topical cream. Eflornithine (Vaniqa), a prescription cream is a primary treatment for women with excessive hair growth.
If you use the above medication, please make sure that know all the side effects.
Some researchers suggested due to the complex nature of the syndrome, management is usually a long and troublesome process.
Fennel (Foeniculum vulgare) is a plant species of the genus, belonging to Apiaceae (Umbelliferae), native to the Mediterranean.
The herb or food has been used in traditional and herbal medicine as a warming, carminative, antispasmodic, and depressant agent and to stimulate the appetite, ease indigestion, soothe coughing, reduce intestinal spasms, regulate the menstrual cycle, and relieve PMS,...
The double-blind study, using an ethanolic extract of Fennel, obtained by a Soxhlet apparatus to test the efficacy against the expression of idiopathic hirsutism of a total of 38 patients, includes women with idiopathic hirsutism, a normal ovulatory menstrual cycle and normal levels of serum androgens but exhibited male growth pattern were selected to participate.
All patients were assigned randomly to receive either topical cream containing 1%, 2% of Fennel extract, or placebo.
At the end of the experiment, researchers found that the application of fennel cream exerts a significant effect in reducing hair growth diameter compared to placebo.
Fennel cream with a 2% concentration displayed a strongly inhibited activity compared to cream with 1%.
Specifically, the mean values of hair diameter reduction were 7.8%, 18.3%, and -0.5% for patients receiving the creams containing 1%, 2%, and 0% (placebo) respectively, without inducing any untolerated adverse effects.
These results suggested that fennel ethanolic extract in reducing male hair growth patterns may be attributed to estrogenic properties in the activation of the molecular pathways involved in the estrogen-mediated induction of hair growth.
Dr. Ozra Akh, the lead author said, "Estrogens harness the making of dihydrotestosterone (DHT) in the papilla cells of the skin by controlling 5-alfa reductase enzyme or increasing the conversion of testosterone to weaker androgens and decreasing the testosterone available for conversion to DHT".
Truly, in the review of literature of randomized, double-blind, placebo-controlled clinical trial carried out from 2009 to 2011, in Sari, Iran with a total of 44 women with mild to moderate idiopathic hirsutism, researchers assigned participants either to the group of 22 treated with fennel gel 3% or the control group received placebo.
The mean age of both groups is not much different at 26.9±6.7 and 25.6±4.3 years in the case and control group, respectively, the researchers after taking into account co and confounders indicated that the application of fennel gel 3% demonstrates a significant effect in the reduction of the thickness of facial hair in micrometer by microscope compared to placebo, after 24 weeks of treatment.
The results of the score of both groups were compared to the baseline taken before the experiment
Although no severity of side effects was found during the period, 4 patients complained of itching (3 in the case group) and 4 patients complained of irritation and itching (3 in the case group).
In comparison to the results of 2 experiments used in the article, both 2% gel and 3% gel exerted a similar efficacy in treating idiopathic hirsutism in patients with mild, moderated, and excessive hair growth.
Truly, the property in reduced unwanted hair growth in the study was probably due to the presence of major bioactive phytochemical trans-anethole and di-anethole anti-androgenic effect.
Based on the evidence found, fennel may be considered a reliable and less expensive functional food for the treatment of idiopathic hirsutism.
However, due to the limited information provided by the small sample size, short period time of follow-up and the case severity does not include in both studies, Additional studies are necessary to reconfirm fennel anti Hirsutism viability.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Antihirsutism activity of Fennel (fruits of Foeniculum vulgare) extract. A double-blind placebo-controlled study by Javidnia K1, Dastgheib L, Mohammadi Samani S, Nasiri A.(PubMed)
(2) The effect of fennel (Foeniculum vulgare) gel 3% in decreasing hair thickness in idiopathic mild to moderate hirsutism, A randomized placebo-controlled clinical trial by Ozra Akha, MD,1 Khadijeh Rabiei, MD,*,2 Zahra Kashi, MD,1 Adele Bahar, MD,1 Elham Zaeif-Khorasani, MD,1 Mehrnoush Kosaryan, MD,3 Majid Saeedi, Ph.D.,4 Mohammad Ali Ebrahimzadeh, Ph.D.,5 and Omid Emadian, MD(PubMed)
#CarrotOilExtract and #CarrotJuices Stop #ColonCancer Spreading by Increased Apoptotic Cell Death and Inhibited Proliferation, Scientists Say
Kyle J. Norton
Carrots may have a profound and substantial effect on blocking colon cancer cells from spreading, some scientists suggested.
Colon cancer, the third most common type of cancer in the United States, is a condition characterized by cell growth disorderly and uncontrollably in colon tissue. At the later stage, the cancerous cells may infect other healthy tissue and organs a distance away from the original site.
According to statistics provided by the American cancer society, in the US, 135,430 new cases of colon cancers were diagnosed and 50,260 patients died from colon and rectal cancers in 2017.
Sadly. 1 in 22 men and 1 in 24 women will be diagnosed with colorectal cancer in their lifetime.
The exact causes of colon cancer are unknown, some researchers suggested that increasing age, African-American race, high fat intake, a family history of colorectal cancer, patients with polyps in the large intestine, and inflammatory bowel diseases, and chronic ulcerative colitis are associated to increase the risk of the disease onset.
Besides the symptoms of common cancer, patients with colon cancer may also experience, a change in bowel habits, that lasts longer than 3 weeks, persistent rectal bleeding or blood in your stool,... and abdominal discomforts, such as cramps, gas, or pain.
Dr. O'Neill AM, the lead scientist in concern about the Western diet in the risk of colon cancer, wrote in his vitro, "Human colon cancer growth is accelerated in animals that are obese and insulin resistant due to the consumption of a high-fat Western diet (HFWD)"(4).
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belongings to the family Apiaceae, native to Asia and Europe.
In an aim to evaluate the effect of carrot intake and risk of colon cancer, researchers at the Technical University of Munich conducted a randomized cross-over trial of twenty-two healthy young men on a low-carotenoid diet consuming 330 ml tomato or carrot juice per day for 2 weeks with intervention periods preceded by 2-week depletion phases.
At the end of the experiment, researchers found that increased marks of beta-carotene and alpha-carotene were found in the collected feces.
Further analysis of fecal water, researchers indicated that intake of tomato and carrot juice demonstrates a huge activity in the induction of cytotoxic and antiproliferative effects on colon adenocarcinoma cells (HT29) in a high dose-dependent manner without alternating the bile acid concentrations, activities of the bacterial enzymes beta-glucosidase and beta-glucuronidase.
Moreover, intake of tomato and carrot juice also decreased fecal water pH, another indication of anti-colon activity that was attributed to short chain fatty acids (SCFAs) concentration with function in regulated cecal and colonic metabolism and modulated histone acetylation in human HT29 colon cancer cells.
After taking into account other confounders, Dr. Schnäbele K, the lead author said, "2-week interventions with carotenoid-rich juices led only to minor changes in investigated luminal biomarkers relevant to colon carcinogenesis".
Additionally, in the reaffirmation of wild carrots used in folk medicine throughout the world for anticancer and antioxidant activities, researchers at the joint study lead by the University of Surrey conducted an experiment to evaluate the effect of pentane fraction (F1) and the 1:1 pentane: diethyl ether fraction (F2) of the Daucus Carota oil extract (DCOE) in human colon adenocarcinoma cell lines (HT-29 and Caco-2).
The results of the study suggested that the application of the extract F1 and F2 exerts a profound effect in the inhibition of colon cell proliferation in a dose-dependent manner.
According to the Flow cytometric analysis, both fractions ameliorated colon cell expression through significantly induced sub-G1 phase accumulation and increased apoptotic cell death.
In the Western blot assay, researchers found that the application of F1 and F2 also reduces cancer cell proliferation through the activation of caspase-3 which is considered a 'death-switch' in colorectal cancer cells.
Administration of F1 and F2 also increased expression of Bax in penetration of cancer mitochondrial outer membrane to mediate cell death by apoptosis. and p53 with function exhibited cancer cell growth arrest and inhibited cancer cell proliferation.
The fractions also decreased levels of Bcl-2 in inhibited PARP cleavage activity in the facilitation of colon cancer cell apoptosis.
This implication suggested that F1 or F2 inhibited colon cancer cells through ameliorated expression of the phosphatidyl inositol 3-kinase (PI3K) pathway which has the function to act as a key mediator of cell metabolism and cell growth at different levels.
More importantly, the injection of DCOE fractions (F1 and F2) also attenuated cell proliferation by inducing cell cycle arrest and apoptosis in HT-29 cells.
The findings strongly suggested that carrots can be considered as a functional food in the prevention and treatment of colon cancer. But Intake of carrot supplements should be taken with care to prevent acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299
Sources
(1) Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shebaby WN1, Bodman-Smith KB1, Mansour A2, Mroueh M3, Taleb RI4, El-Sibai M4, Daher CF(PubMed)
(2) Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans by Schnäbele K1, Briviba K, Bub A, Roser S, Pool-Zobel BL, Rechkemmer G(PubMed)
(3) Inhibitory effects of feeding with carrots or (-)-falcarinol on development of azoxymethane-induced preneoplastic lesions in the rat colon by Kobaek-Larsen M1, Christensen LP, Vach W, Ritskes-Hoitinga J, Brandt K(PubMed)
(4) High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer by O'Neill AM1, Burrington CM2, Gillaspie EA3, Lynch DT2, Horsman MJ2, Greene MW(PubMed)
Carrots may have a profound and substantial effect on blocking colon cancer cells from spreading, some scientists suggested.
Colon cancer, the third most common type of cancer in the United States, is a condition characterized by cell growth disorderly and uncontrollably in colon tissue. At the later stage, the cancerous cells may infect other healthy tissue and organs a distance away from the original site.
According to statistics provided by the American cancer society, in the US, 135,430 new cases of colon cancers were diagnosed and 50,260 patients died from colon and rectal cancers in 2017.
Sadly. 1 in 22 men and 1 in 24 women will be diagnosed with colorectal cancer in their lifetime.
The exact causes of colon cancer are unknown, some researchers suggested that increasing age, African-American race, high fat intake, a family history of colorectal cancer, patients with polyps in the large intestine, and inflammatory bowel diseases, and chronic ulcerative colitis are associated to increase the risk of the disease onset.
Besides the symptoms of common cancer, patients with colon cancer may also experience, a change in bowel habits, that lasts longer than 3 weeks, persistent rectal bleeding or blood in your stool,... and abdominal discomforts, such as cramps, gas, or pain.
Dr. O'Neill AM, the lead scientist in concern about the Western diet in the risk of colon cancer, wrote in his vitro, "Human colon cancer growth is accelerated in animals that are obese and insulin resistant due to the consumption of a high-fat Western diet (HFWD)"(4).
Carrot, a root vegetable with an orange color is a subspecies of Daucus carota, belongings to the family Apiaceae, native to Asia and Europe.
In an aim to evaluate the effect of carrot intake and risk of colon cancer, researchers at the Technical University of Munich conducted a randomized cross-over trial of twenty-two healthy young men on a low-carotenoid diet consuming 330 ml tomato or carrot juice per day for 2 weeks with intervention periods preceded by 2-week depletion phases.
At the end of the experiment, researchers found that increased marks of beta-carotene and alpha-carotene were found in the collected feces.
Further analysis of fecal water, researchers indicated that intake of tomato and carrot juice demonstrates a huge activity in the induction of cytotoxic and antiproliferative effects on colon adenocarcinoma cells (HT29) in a high dose-dependent manner without alternating the bile acid concentrations, activities of the bacterial enzymes beta-glucosidase and beta-glucuronidase.
Moreover, intake of tomato and carrot juice also decreased fecal water pH, another indication of anti-colon activity that was attributed to short chain fatty acids (SCFAs) concentration with function in regulated cecal and colonic metabolism and modulated histone acetylation in human HT29 colon cancer cells.
After taking into account other confounders, Dr. Schnäbele K, the lead author said, "2-week interventions with carotenoid-rich juices led only to minor changes in investigated luminal biomarkers relevant to colon carcinogenesis".
Additionally, in the reaffirmation of wild carrots used in folk medicine throughout the world for anticancer and antioxidant activities, researchers at the joint study lead by the University of Surrey conducted an experiment to evaluate the effect of pentane fraction (F1) and the 1:1 pentane: diethyl ether fraction (F2) of the Daucus Carota oil extract (DCOE) in human colon adenocarcinoma cell lines (HT-29 and Caco-2).
The results of the study suggested that the application of the extract F1 and F2 exerts a profound effect in the inhibition of colon cell proliferation in a dose-dependent manner.
According to the Flow cytometric analysis, both fractions ameliorated colon cell expression through significantly induced sub-G1 phase accumulation and increased apoptotic cell death.
In the Western blot assay, researchers found that the application of F1 and F2 also reduces cancer cell proliferation through the activation of caspase-3 which is considered a 'death-switch' in colorectal cancer cells.
Administration of F1 and F2 also increased expression of Bax in penetration of cancer mitochondrial outer membrane to mediate cell death by apoptosis. and p53 with function exhibited cancer cell growth arrest and inhibited cancer cell proliferation.
The fractions also decreased levels of Bcl-2 in inhibited PARP cleavage activity in the facilitation of colon cancer cell apoptosis.
This implication suggested that F1 or F2 inhibited colon cancer cells through ameliorated expression of the phosphatidyl inositol 3-kinase (PI3K) pathway which has the function to act as a key mediator of cell metabolism and cell growth at different levels.
More importantly, the injection of DCOE fractions (F1 and F2) also attenuated cell proliferation by inducing cell cycle arrest and apoptosis in HT-29 cells.
The findings strongly suggested that carrots can be considered as a functional food in the prevention and treatment of colon cancer. But Intake of carrot supplements should be taken with care to prevent acute liver toxicity.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Loose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Home page http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bio Science, ISSN 0975-6299
Sources
(1) Daucus carota Pentane-Based Fractions Suppress Proliferation and Induce Apoptosis in Human Colon Adenocarcinoma HT-29 Cells by Inhibiting the MAPK and PI3K Pathways by Shebaby WN1, Bodman-Smith KB1, Mansour A2, Mroueh M3, Taleb RI4, El-Sibai M4, Daher CF(PubMed)
(2) Effects of carrot and tomato juice consumption on faecal markers relevant to colon carcinogenesis in humans by Schnäbele K1, Briviba K, Bub A, Roser S, Pool-Zobel BL, Rechkemmer G(PubMed)
(3) Inhibitory effects of feeding with carrots or (-)-falcarinol on development of azoxymethane-induced preneoplastic lesions in the rat colon by Kobaek-Larsen M1, Christensen LP, Vach W, Ritskes-Hoitinga J, Brandt K(PubMed)
(4) High-fat Western diet-induced obesity contributes to increased tumor growth in mouse models of human colon cancer by O'Neill AM1, Burrington CM2, Gillaspie EA3, Lynch DT2, Horsman MJ2, Greene MW(PubMed)
#Coffee Intake Daily and Regularly Is Associated with a Reduced Risk of #MetabolicSyndrome, Scientists Say
By Kyle J. Norton
Coffee consumed daily and regularly may have a substantial and potential effect in blocking the onset of metabolic syndrome, some scientists suggested.
Metabolic Syndrome is a group of risk factors associated with the development of cardiovascular disease and type 2 diabetes, including high blood pressure, abnormally high blood cholesterol, and triglyceride levels,.....
According to the statistic, about a quarter of the US population have metabolic syndrome and the numbers are increasing at an alarming rate.
The Western diet with a high of saturated and trans, refined sugar, and salt, and processed foods, is associated with the early onset of the condition.
Dr. Christos Pitsavos, in the evaluation of the effect of diet on the risk metabolic syndrome, wrote, "People with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle".
These statements suggested that everyone can prevent the development of the syndrome through modification of their daily diet accompanied by a change to a healthy lifestyle.
The doctor continued, " During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products. Such diets need not be restricted in total fat intake as long as energy intake does not exceed caloric expenditure and if they emphasize predominantly vegetable oils that have a low content of saturated fats and partially hydrogenated oils".
Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the West, made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.
According to the search of the database of PubMed and the China National Knowledge Infrastructure (CNKI) for relevant articles published between 1 January 1999 and 31 May 2015, including 11 published reports and 13 studies with a total of 159,805 participants eligible for our meta-analysis, the relatively odd risk ratio of metabolic syndrome between the highest vs lowest category of coffee consumption was 0.872
The review also observed a nonlinear relationship between coffee and coffee caffeine consumption in the amelioration of risk of metabolic syndrome, by dose-response analysis.
Additionally, in a cross-sectional population-based survey of 8,821 adults (51.4% female) conducted in Krakow, Poland. to evaluate the coffee and tea consumption and risk of metabolic syndrome, using food frequency questionnaires, researchers after the observation of the questionnaire returned from participants expressed that there is an interesting association between high coffee consumption of 3 cups and the clusters of lower BMI, waist circumference, systolic and diastolic blood pressure, triglycerides, and higher HDL cholesterol compared to those drinking less than 1 cup/day.
The study apparently indicated that people drinking 3 cups of coffee daily and regularly have a favorably ameliorated risk of metabolic syndrome even after adjusting for potential confounding factors.
More importantly, the study also pointed out that high coffee consumption was negatively associated with waist circumference, hypertension, and triglycerides in women but not in men.
Furthermore, in animal evaluation of the effect of coffee drinking on clinical markers of diabetes and metabolic syndrome in Zucker rats including Diabetic Zucker rats with metabolic syndrome and control Zucker rats, researchers at the Fluminense Federal Institute showed that animals received daily doses of coffee by gavage for 30 days express a substantially decreased risk of metabolic syndrome by reducing serum glucose, total cholesterol, and triglycerides, compared to non-treatment group.
Dr. Abrahão SA, the lead researcher said, "The results demonstrate that treatment with a roasted coffee drink, because of its hypoglycemic and hypolipidemic effect, is efficient in the protection of animals with metabolic syndrome and diabetes mellitus type 2".
The findings from the above studies suggested that coffee drinking daily and regularly have a favorably profound effect in decreasing the risk of metabolic syndrome, particularly in women.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Coffee consumption and risk of the metabolic syndrome: A meta-analysis by Shang F1, Li X1, Jiang X2.(PubMed)
(2) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3.(PubMed)
(3) Diet, Exercise and the Metabolic Syndrome by Christos Pitsavos, Christos Pitsavos, Demosthenes Panagiotakos,, Michael Weinem, and Christodoulos Stefanadis. (PMC)
Coffee consumed daily and regularly may have a substantial and potential effect in blocking the onset of metabolic syndrome, some scientists suggested.
Metabolic Syndrome is a group of risk factors associated with the development of cardiovascular disease and type 2 diabetes, including high blood pressure, abnormally high blood cholesterol, and triglyceride levels,.....
According to the statistic, about a quarter of the US population have metabolic syndrome and the numbers are increasing at an alarming rate.
The Western diet with a high of saturated and trans, refined sugar, and salt, and processed foods, is associated with the early onset of the condition.
Dr. Christos Pitsavos, in the evaluation of the effect of diet on the risk metabolic syndrome, wrote, "People with the metabolic syndrome may benefit from intensive lifestyle modifications including dietary changes and adopting a physically more active lifestyle".
These statements suggested that everyone can prevent the development of the syndrome through modification of their daily diet accompanied by a change to a healthy lifestyle.
The doctor continued, " During the last decades increasing scientific evidence has emerged that protective health effects can be obtained from diets that are rich in fruits, vegetables, legumes, and whole grains, and which include fish, nuts, and low-fat dairy products. Such diets need not be restricted in total fat intake as long as energy intake does not exceed caloric expenditure and if they emphasize predominantly vegetable oils that have a low content of saturated fats and partially hydrogenated oils".
Coffee, second to green tea, is a popular and social beverage all over the world, particularly in the West, made from roast beans from the Coffea plant, native to tropical Africa and Madagascar.
According to the search of the database of PubMed and the China National Knowledge Infrastructure (CNKI) for relevant articles published between 1 January 1999 and 31 May 2015, including 11 published reports and 13 studies with a total of 159,805 participants eligible for our meta-analysis, the relatively odd risk ratio of metabolic syndrome between the highest vs lowest category of coffee consumption was 0.872
The review also observed a nonlinear relationship between coffee and coffee caffeine consumption in the amelioration of risk of metabolic syndrome, by dose-response analysis.
Additionally, in a cross-sectional population-based survey of 8,821 adults (51.4% female) conducted in Krakow, Poland. to evaluate the coffee and tea consumption and risk of metabolic syndrome, using food frequency questionnaires, researchers after the observation of the questionnaire returned from participants expressed that there is an interesting association between high coffee consumption of 3 cups and the clusters of lower BMI, waist circumference, systolic and diastolic blood pressure, triglycerides, and higher HDL cholesterol compared to those drinking less than 1 cup/day.
The study apparently indicated that people drinking 3 cups of coffee daily and regularly have a favorably ameliorated risk of metabolic syndrome even after adjusting for potential confounding factors.
More importantly, the study also pointed out that high coffee consumption was negatively associated with waist circumference, hypertension, and triglycerides in women but not in men.
Furthermore, in animal evaluation of the effect of coffee drinking on clinical markers of diabetes and metabolic syndrome in Zucker rats including Diabetic Zucker rats with metabolic syndrome and control Zucker rats, researchers at the Fluminense Federal Institute showed that animals received daily doses of coffee by gavage for 30 days express a substantially decreased risk of metabolic syndrome by reducing serum glucose, total cholesterol, and triglycerides, compared to non-treatment group.
Dr. Abrahão SA, the lead researcher said, "The results demonstrate that treatment with a roasted coffee drink, because of its hypoglycemic and hypolipidemic effect, is efficient in the protection of animals with metabolic syndrome and diabetes mellitus type 2".
The findings from the above studies suggested that coffee drinking daily and regularly have a favorably profound effect in decreasing the risk of metabolic syndrome, particularly in women.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299.
Sources
(1) Coffee consumption and risk of the metabolic syndrome: A meta-analysis by Shang F1, Li X1, Jiang X2.(PubMed)
(2) Association of daily coffee and tea consumption and metabolic syndrome: results from the Polish arm of the HAPIEE study by Grosso G1,2, Stepaniak U3, Micek A3, Topor-Mądry R3, Pikhart H4, Szafraniec K3, Pająk A3.(PubMed)
(3) Diet, Exercise and the Metabolic Syndrome by Christos Pitsavos, Christos Pitsavos, Demosthenes Panagiotakos,, Michael Weinem, and Christodoulos Stefanadis. (PMC)
#GreenTea#EGCG Processes Anti #BacterialInfection and #InfectiousDiseases, Scientist Find
Kyle J. Norton
Green tea may have a therapeutic and positive effect in protecting the lung against bacteria that cause atypical pneumonia, some scientists suggested.
Atypical pneumonia is an infection of the lower respiratory tract. The disease is accounted for 7%‐20% of community‐acquired pneumonia (CAP).
Most cases of atypical pneumonia are caused by Streptococcus pneumonia. However, Other bacteria such as Mycoplasma pneumonia, Chlamydia pneumonia, Chlamydia psittaci, and Legionella pneumophila are also found in some patients with atypical pneumonia.
Conventional medicine used for the treatment of typical pneumonia, such as Macrolide antibiotics: Macrolide drugs are the preferred treatment for children and adults. Macrolides include azithromycin(Zithromax®) and clarithromycin may be effective. However, they can induce certain side effects including gastrointestinal discomfort.
The article Popular Antibiotics May Carry Serious Side Effects BY JANE E. BRODY, in the explanation of a patient who just took on a dose of antibiotic, wrote," After just one dose, he developed widespread pain and weakness." and " (He is) unable to walk uphill, climb stairs or see clearly, his symptoms included dry eyes, mouth, and skin; ringing in his ears; delayed urination; uncontrollable shaking; burning pain in his eyes and feet; occasional tingling in his hands and feet; heart palpitations; and muscle spasms in his back and around his eyes".
If you are currently taking antibiotics for the treatment of a disease, please make sure that you discuss the side effects with your doctor.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
With an aim to find a natural solution with antibacterial potential, researchers at the University of Duisburg-Essen conducted a study to examine whether green tea processes antibacterial activity against the onset of infectious diseases.
In the final report of the experiment, researcher wrote, the minimum inhibitory concentrations against bacteria were 10–100-fold higher compared to the antiviral property with the same volume.
EGCG used alone or in combination with different antibiotics exerts a significant activity against a number of bacteria including multidrug-resistant strains such as methicillin-resistant Staphylococcus aureus Stenotrophomonas maltophilia, the group of bacteria that cause atypical pneumonia.
The additional analysis suggested that EGCG displays efficacy in inhibiting bacteria by binding to lipid membranes and affecting the folic acid metabolism of bacteria and fungi by inhibiting the cytoplasmic enzyme dihydrofolate reductase.
Dihydrofolate reductase, or DHFR, an enzyme that reduces hydrofolic acid to tetrahydrofolic acid, plays an essential role in the building of the DNA of the cells.
Furthermore, in an aim to find a natural anti-antibacterial remedy in replacing the ineffective antibiotics as well as the concerns over the toxicity of the mainstay of treatment against Stenotrophomonas maltophilia, a main cause of atypical pneumonia, researchers at the Barts & The London NHS Trust conducted a study to examine the effect of Epigallocatechin-3-gallate (EGCG), the major catechin found in green tea, against a number of bacteria.
In a total of 40 clinical isolates of S. maltophilia used in the experiment, scientists found that EGCG exerts a promising in vitro antimicrobial activity against S. maltophilia. At the dose of 512 mg/ L., EGCG inhibited bacteria in the range of 50% and 90%.
Moreover, in the examination of tea leaves organic compounds involved in the defense of the plants against invading pathogens including insects, bacteria, fungi, and viruses, researchers showed that tea flavonoids and teas exert great antimicrobial effects against foodborne and other pathogenic bacteria, virulent protein toxins produced by some of the bacteria, virulent bacteriophages, pathogenic viruses, and fungi.
Taken all together, green tea and its bioactive ingredient EGCG may be considered a functional food and supplement respectively in protecting the human body against bacteria, particularly, Streptococcus pneumonia in the initiation of the onset of bacterial infection and infectious diseases, including atypical pneumonia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea by J Steinmann,1 J Buer,1 T Pietschmann,2 and E Steinmann(PMC)
(2) Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia by Gordon NC1, Wareham DW(PubMed)
(3) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas Mendel Friedman
Green tea may have a therapeutic and positive effect in protecting the lung against bacteria that cause atypical pneumonia, some scientists suggested.
Atypical pneumonia is an infection of the lower respiratory tract. The disease is accounted for 7%‐20% of community‐acquired pneumonia (CAP).
Most cases of atypical pneumonia are caused by Streptococcus pneumonia. However, Other bacteria such as Mycoplasma pneumonia, Chlamydia pneumonia, Chlamydia psittaci, and Legionella pneumophila are also found in some patients with atypical pneumonia.
Conventional medicine used for the treatment of typical pneumonia, such as Macrolide antibiotics: Macrolide drugs are the preferred treatment for children and adults. Macrolides include azithromycin(Zithromax®) and clarithromycin may be effective. However, they can induce certain side effects including gastrointestinal discomfort.
The article Popular Antibiotics May Carry Serious Side Effects BY JANE E. BRODY, in the explanation of a patient who just took on a dose of antibiotic, wrote," After just one dose, he developed widespread pain and weakness." and " (He is) unable to walk uphill, climb stairs or see clearly, his symptoms included dry eyes, mouth, and skin; ringing in his ears; delayed urination; uncontrollable shaking; burning pain in his eyes and feet; occasional tingling in his hands and feet; heart palpitations; and muscle spasms in his back and around his eyes".
If you are currently taking antibiotics for the treatment of a disease, please make sure that you discuss the side effects with your doctor.
Green tea, a precious drink processes a number of health benefits known to almost everyone in Asia and the Western world.
With an aim to find a natural solution with antibacterial potential, researchers at the University of Duisburg-Essen conducted a study to examine whether green tea processes antibacterial activity against the onset of infectious diseases.
In the final report of the experiment, researcher wrote, the minimum inhibitory concentrations against bacteria were 10–100-fold higher compared to the antiviral property with the same volume.
EGCG used alone or in combination with different antibiotics exerts a significant activity against a number of bacteria including multidrug-resistant strains such as methicillin-resistant Staphylococcus aureus Stenotrophomonas maltophilia, the group of bacteria that cause atypical pneumonia.
The additional analysis suggested that EGCG displays efficacy in inhibiting bacteria by binding to lipid membranes and affecting the folic acid metabolism of bacteria and fungi by inhibiting the cytoplasmic enzyme dihydrofolate reductase.
Dihydrofolate reductase, or DHFR, an enzyme that reduces hydrofolic acid to tetrahydrofolic acid, plays an essential role in the building of the DNA of the cells.
Furthermore, in an aim to find a natural anti-antibacterial remedy in replacing the ineffective antibiotics as well as the concerns over the toxicity of the mainstay of treatment against Stenotrophomonas maltophilia, a main cause of atypical pneumonia, researchers at the Barts & The London NHS Trust conducted a study to examine the effect of Epigallocatechin-3-gallate (EGCG), the major catechin found in green tea, against a number of bacteria.
In a total of 40 clinical isolates of S. maltophilia used in the experiment, scientists found that EGCG exerts a promising in vitro antimicrobial activity against S. maltophilia. At the dose of 512 mg/ L., EGCG inhibited bacteria in the range of 50% and 90%.
Moreover, in the examination of tea leaves organic compounds involved in the defense of the plants against invading pathogens including insects, bacteria, fungi, and viruses, researchers showed that tea flavonoids and teas exert great antimicrobial effects against foodborne and other pathogenic bacteria, virulent protein toxins produced by some of the bacteria, virulent bacteriophages, pathogenic viruses, and fungi.
Taken all together, green tea and its bioactive ingredient EGCG may be considered a functional food and supplement respectively in protecting the human body against bacteria, particularly, Streptococcus pneumonia in the initiation of the onset of bacterial infection and infectious diseases, including atypical pneumonia.
Natural Medicine for Fatty Liver And Obesity Reversal - The Revolutionary Findings To Achieve Optimal Health And Lose Weight
How To Get Rid Of Eye Floaters
Contrary To Professional Prediction, Floaters Can Be Cured Naturally
Ovarian Cysts And PCOS Elimination
Holistic System In Existence That Will Show You How To
Permanently Eliminate All Types of Ovarian Cysts Within 2 Months
Back to Kyle J. Norton's Homepage http://kylejnorton.blogspot.ca
Author Biography
Kyle J. Norton (Scholar, Master of Nutrition, All right reserved)
Health article writer and researcher; Over 10.000 articles and research papers have been written and published online, including worldwide health, ezine articles, article base, health blogs, self-growth, best before it's news, the Karate GB Daily, etc.,.
Named TOP 50 MEDICAL ESSAYS FOR ARTISTS & AUTHORS TO READ by Disilgold.com Named 50 of the best health Tweeters Canada - Huffington Post
Nominated for shorty award over last 4 years
Some articles have been used as references in medical research, such as the international journal Pharma and Bioscience, ISSN 0975-6299
Sources
(1) Anti-infective properties of epigallocatechin-3-gallate (EGCG), a component of green tea by J Steinmann,1 J Buer,1 T Pietschmann,2 and E Steinmann(PMC)
(2) Antimicrobial activity of the green tea polyphenol (-)-epigallocatechin-3-gallate (EGCG) against clinical isolates of Stenotrophomonas maltophilia by Gordon NC1, Wareham DW(PubMed)
(3) Overview of antibacterial, antitoxin, antiviral, and antifungal activities of tea flavonoids and teas Mendel Friedman